{"id":43010,"date":"2015-09-17T11:25:58","date_gmt":"2015-09-17T16:25:58","guid":{"rendered":"https:\/\/content.findlaw-admin.com\/ability-legal\/contracts\/uncategorized\/agreement-and-plan-of-merger-amgen-inc-and-immunex-corp.html"},"modified":"2015-09-17T11:25:58","modified_gmt":"2015-09-17T16:25:58","slug":"agreement-and-plan-of-merger-amgen-inc-and-immunex-corp","status":"publish","type":"corporate_contracts","link":"https:\/\/corporate.findlaw.com\/contracts\/planning\/agreement-and-plan-of-merger-amgen-inc-and-immunex-corp.html","title":{"rendered":"Agreement and Plan of Merger &#8211; Amgen Inc. and Immunex Corp."},"content":{"rendered":"<pre>\n                          AGREEMENT AND PLAN OF MERGER\n\n                                  BY AND AMONG\n\n                                   AMGEN INC.,\n\n                              AMS ACQUISITION INC.\n\n                                       AND\n\n                               IMMUNEX CORPORATION\n\n                          DATED AS OF DECEMBER 16, 2001\n\n\n\n                                TABLE OF CONTENTS\n                                -----------------\n\n<\/pre>\n<table>\n<caption>\n<p><s>          <c><br \/>\nARTICLE 1    The Merger&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;  1<\/p>\n<p>Section 1.1    The Merger &#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;  1<br \/>\nSection 1.2    Closing&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.  1<br \/>\nSection 1.3    Effect of the Merger&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;  2<br \/>\nSection 1.4    Articles of Incorporation; Bylaws&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;..  2<br \/>\nSection 1.5    Directors and Officers of the Surviving Corporation&#8230;&#8230;&#8230;..  2<br \/>\nSection 1.6    Directors of Parent&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.  2<\/p>\n<p>ARTICLE 2.   Conversion of Securities; Exchange of Certificates&#8230;&#8230;&#8230;&#8230;..  2<\/p>\n<p>Section 2.1    Conversion of Securities&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;..  2<br \/>\nSection 2.2    Exchange of Certificates&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;..  4<br \/>\nSection 2.3    Stock Transfer Books&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;  7<br \/>\nSection 2.4    Stock Options&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.  7<br \/>\nSection 2.5    Employee Stock Purchase Plan&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.  8<br \/>\nSection 2.6    Employment Agreement&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;  8<br \/>\nSection 2.7    AHP Agreements&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;  8<br \/>\nSection 2.8    Role of Seattle and Rhode Island Following the Merger&#8230;&#8230;&#8230;  9<\/p>\n<p>ARTICLE 3.   Representations and Warranties of the Company&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.  9<\/p>\n<p>Section 3.1    Organization and Qualification; Subsidiaries&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;  9<br \/>\nSection 3.2    Articles of Incorporation and Bylaws; Corporate Books<br \/>\n                 and Records&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.  9<br \/>\nSection 3.3    Capitalization&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 10<br \/>\nSection 3.4    Authority&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 11<br \/>\nSection 3.5    No Conflict; Required Filings and Consents&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 11<br \/>\nSection 3.6    Permits; Compliance With Law&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 12<br \/>\nSection 3.7    SEC Filings; Financial Statements&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 13<br \/>\nSection 3.8    Absence of Certain Changes or Events&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 13<br \/>\nSection 3.9    Employee Benefit Plans&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 14<br \/>\nSection 3.10   Labor and Other Employment Matters&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 16<br \/>\nSection 3.11   Tax Treatment&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 17<br \/>\nSection 3.12   Contracts&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 17<br \/>\nSection 3.13   Litigation&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 18<br \/>\nSection 3.14   Environmental Matters&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 18<br \/>\nSection 3.15   Intellectual Property&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 19<br \/>\nSection 3.16   Taxes&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 20<br \/>\nSection 3.17   Insurance&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 20<br \/>\nSection 3.18   Properties&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 20<br \/>\nSection 3.19   Regulatory Compliance&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 21<br \/>\nSection 3.20   Opinion of Financial Advisor&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 22<br \/>\nSection 3.21   Vote Required&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 22<br \/>\nSection 3.22   Brokers&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 22<\/p>\n<p>ARTICLE 4.   Representations and Warranties of Parent and Merger Sub&#8230;&#8230;&#8230; 22<\/p>\n<p>Section 4.1    Organization and Qualification; Subsidiaries&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 22<br \/>\nSection 4.2    Certificate of Incorporation and Bylaws; Corporate Books<br \/>\n                  and Records&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 23<br \/>\n<\/c><\/s><\/caption>\n<\/table>\n<p>                                       i<\/p>\n<table>\n<caption>\n<s>         <c><br \/>\nSection 4.3    Capitalization&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 23<br \/>\nSection 4.4    Authority Relative to This Agreement&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 24<br \/>\nSection 4.5    No Conflict; Required Filings and Consents&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 24<br \/>\nSection 4.6    Permits; Compliance With Law&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 25<br \/>\nSection 4.7    SEC Filings; Financial Statements&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 25<br \/>\nSection 4.8    Absence of Certain Changes or Events&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 26<br \/>\nSection 4.9    Litigation&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 26<br \/>\nSection 4.10   Environmental Matters&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 27<br \/>\nSection 4.11   Intellectual Property&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 27<br \/>\nSection 4.12   Regulatory Compliance&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 27<br \/>\nSection 4.13   Tax Treatment&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 28<br \/>\nSection 4.14   Ownership of Merger Sub; No Prior Activities&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 28<br \/>\nSection 4.15   Opinion of Financial Advisor&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 28<br \/>\nSection 4.16   Vote Required&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 28<br \/>\nSection 4.17   Brokers&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 28<br \/>\nSection 4.18   Sufficient Funds&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 28<\/p>\n<p>ARTICLE 5.  Covenants&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 28<\/p>\n<p>Section 5.1    Conduct of Business by the Company Pending the Closing&#8230;&#8230;.. 28<br \/>\nSection 5.2    Conduct of Business by Parent Pending the Closing&#8230;&#8230;&#8230;&#8230;. 32<br \/>\nSection 5.3    Cooperation&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 33<br \/>\nSection 5.4    Tax-Free Reorganization Treatment&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 33<br \/>\nSection 5.5    Control of Other Party&#8217;s Business&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 33<\/p>\n<p>ARTICLE 6.  Additional Agreements&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 34<\/p>\n<p>Section 6.1    Registration Statement; Proxy Statement&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 34<br \/>\nSection 6.2    Shareholders&#8217; Meetings&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 35<br \/>\nSection 6.3    Access to Information; Confidentiality&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 36<br \/>\nSection 6.4    No Solicitation of Transactions&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 37<br \/>\nSection 6.5    Appropriate Action; Consents; Filings&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 39<br \/>\nSection 6.6    Certain Notices&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 41<br \/>\nSection 6.7    Public Announcements&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 41<br \/>\nSection 6.8    Nasdaq Listing&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 41<br \/>\nSection 6.9    Employee Benefit Matters&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 41<br \/>\nSection 6.10   Indemnification of Directors and Officers&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 42<br \/>\nSection 6.11   Plan of Reorganization&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 43<br \/>\nSection 6.12   Affiliate Letters&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 43<br \/>\nSection 6.13   Section 16 Matters&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 43<br \/>\nSection 6.14   Stock Award Matters&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 43<br \/>\nSection 6.15   Restructure of Transaction&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 44<\/p>\n<p>ARTICLE 7.  Closing Conditions&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 44<\/p>\n<p>Section 7.1    Conditions to Obligations of Each Party Under<br \/>\n                  This Agreement&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 44<br \/>\nSection 7.2    Additional Conditions to Obligations of Parent and<br \/>\n                  Merger Sub&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 45<br \/>\nSection 7.3    Additional Conditions to Obligations of the Company&#8230;&#8230;&#8230;.. 46<\/p>\n<p>ARTICLE 8.  Termination, Amendment and Waiver&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 47<\/p>\n<p>Section 8.1    Termination&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 47<\/p>\n<p><\/c><\/s><\/caption>\n<\/table>\n<p>                                       ii<\/p>\n<table>\n<caption>\n<s>           <c><\/p>\n<p>Section 8.2   Effect of Termination&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 48<br \/>\nSection 8.3   Amendment&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 50<br \/>\nSection 8.4   Waiver&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 50<br \/>\nSection 8.5   Fees and Expenses&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 50<\/p>\n<p>ARTICLE 9.  General Provisions&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 50<\/p>\n<p>Section 9.1   Non-Survival of Representations and Warranties&#8230;&#8230;&#8230;&#8230;&#8230;.. 50<br \/>\nSection 9.2   Notices&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 50<br \/>\nSection 9.3   Certain Definitions&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 52<br \/>\nSection 9.4   Terms Defined Elsewhere&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 58<br \/>\nSection 9.5   Headings&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 61<br \/>\nSection 9.6   Severability&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 61<br \/>\nSection 9.7   Entire Agreement&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 61<br \/>\nSection 9.8   Assignment&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 61<br \/>\nSection 9.9   Parties in Interest&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 61<br \/>\nSection 9.10  Mutual Drafting&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 61<br \/>\nSection 9.11  Governing Law; Consent to Jurisdiction; Waiver of Trial<br \/>\n                by Jury&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 62<br \/>\nSection 9.12  Specific Performance&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;. 63<br \/>\nSection 9.13  Disclosure&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. 63<br \/>\nSection 9.14  Counterparts&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 63<\/p>\n<p>Exhibit 6.12            Form of Affiliate Letter<\/p>\n<p>Exhibit 7.2(c)(i)       Parent Tax Matters Certificate<\/p>\n<p>Exhibit 7.2(c)(ii)      Company Tax Matters Certificate<br \/>\n<\/c><\/s><\/caption>\n<\/table>\n<p>                                      iii<\/p>\n<p>                  AGREEMENT AND PLAN OF MERGER, dated as of December 16, 2001<br \/>\n(this &#8220;Agreement&#8221;), by and among Amgen Inc., a Delaware corporation (&#8220;Parent&#8221;),<br \/>\n       &#8212;&#8212;&#8212;                                                      &#8212;&#8212;<br \/>\nAMS Acquisition Inc., a Washington corporation and a wholly-owned subsidiary of<br \/>\nParent (&#8220;Merger Sub&#8221;), and Immunex Corporation, a Washington corporation (the<br \/>\n         &#8212;&#8212;&#8212;-<br \/>\n&#8220;Company&#8221;).<br \/>\n &#8212;&#8212;-<\/p>\n<p>                  WHEREAS, the respective Boards of Directors of Parent, Merger<br \/>\nSub and the Company have approved the merger of Merger Sub with and into the<br \/>\nCompany (the &#8220;Merger&#8221;) upon the terms and subject to the conditions of this<br \/>\n              &#8212;&#8212;<br \/>\nAgreement and in accordance with the Business Corporation Act of the State of<br \/>\nWashington (the &#8220;WBCA&#8221;);<br \/>\n                 &#8212;-<\/p>\n<p>                  WHEREAS, the respective Boards of Directors of Parent and the<br \/>\nCompany have determined that the Merger is in furtherance of and consistent with<br \/>\ntheir respective business strategies and is in the best interest of their<br \/>\nrespective shareholders, and Parent has approved this Agreement and the Merger<br \/>\nas the sole shareholder of Merger Sub;<\/p>\n<p>                  WHEREAS, as a condition to and inducement to Parent&#8217;s and<br \/>\nMerger Sub&#8217;s willingness to enter into this Agreement, simultaneously with the<br \/>\nexecution of this Agreement, American Home Products Corporation, a Delaware<br \/>\ncorporation and shareholder of the Company (&#8220;AHP&#8221;), is entering into a<br \/>\nShareholder Voting Agreement with Parent and Merger Sub (the &#8220;Voting<br \/>\n                                                              &#8212;&#8212;<br \/>\nAgreement&#8221;);<br \/>\n&#8212;&#8212;&#8212;<\/p>\n<p>                  WHEREAS, for federal income tax purposes, it is intended that<br \/>\nthe Merger shall qualify as a reorganization within the meaning of Section<br \/>\n368(a) of the Internal Revenue Code of 1986, as amended (the &#8220;Code&#8221;); and<br \/>\n                                                              &#8212;-<\/p>\n<p>                  WHEREAS, certain capitalized terms used herein are defined<br \/>\nin Section 9.3;<\/p>\n<p>                  NOW, THEREFORE, in consideration of the foregoing and the<br \/>\nrespective representations, warranties, covenants and agreements set forth in<br \/>\nthis Agreement and intending to be legally bound hereby, the parties hereto<br \/>\nagree as follows:<\/p>\n<p>                                   ARTICLE 1.<br \/>\n                                   THE MERGER<\/p>\n<p>     Section 1.1   The Merger. Upon the terms and subject to satisfaction or<br \/>\n                   &#8212;&#8212;&#8212;-<br \/>\nwaiver of the conditions set forth in this Agreement, and in accordance with the<br \/>\nWBCA, at the Effective Time, Merger Sub shall be merged with and into the<br \/>\nCompany. As a result of the Merger, the separate corporate existence of Merger<br \/>\nSub shall cease and the Company shall continue as the surviving corporation of<br \/>\nthe Merger (the &#8220;Surviving Corporation&#8221;).<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>     Section 1.2   Closing. The closing of the Merger (the &#8220;Closing&#8221;) shall take<br \/>\n                   &#8212;&#8212;-                                  &#8212;&#8212;-<br \/>\nplace on the first Business Day after the satisfaction or waiver (subject to<br \/>\napplicable Law) of the conditions (excluding conditions that, by their nature,<br \/>\ncannot be satisfied until the Closing Date) set forth in Article 7, unless this<br \/>\nAgreement has been theretofore terminated pursuant to its terms or unless<br \/>\nanother time or date is agreed to in writing by the parties hereto (the actual<br \/>\ndate of the Closing being referred to herein as the &#8220;Closing Date&#8221;). The Closing<br \/>\n                                                     &#8212;&#8212;&#8212;&#8212;<br \/>\nshall be held at the offices of Latham &amp; Watkins, 633 West Fifth<br \/>\nStreet, Suite 4000, Los Angeles, California 90071, unless another place is<br \/>\nagreed to in writing by the parties hereto. As soon as practicable after the<br \/>\nClosing Date, the parties hereto shall cause the Merger to be consummated by<br \/>\nfiling articles of<\/p>\n<p>merger relating to the Merger (the &#8220;Articles of Merger&#8221;) with the Secretary of<br \/>\n                                    &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nState of the State of Washington, in such form as required by, and executed in<br \/>\naccordance with the relevant provisions of, the WBCA (the date and time of such<br \/>\nfiling, or if another date and time is specified in such filing, such specified<br \/>\ndate and time, being the &#8220;Effective Time&#8221;).<br \/>\n                          &#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n<p>        Section 1.3   Effect of the Merger. At the Effective Time, the effect<br \/>\n                      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nof the Merger shall be as provided in the applicable provisions of the WBCA.<br \/>\nWithout limiting the generality of the foregoing, at the Effective Time, except<br \/>\nas otherwise provided herein, all the property, rights, privileges, powers and<br \/>\nfranchises of the Company and Merger Sub shall vest in the Surviving<br \/>\nCorporation, and all debts, liabilities and duties of the Company and Merger Sub<br \/>\nshall become the debts, liabilities and duties of the Surviving Corporation.<\/p>\n<p>        Section 1.4   Articles of Incorporation; Bylaws.<br \/>\n                      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>        (a) Articles of Incorporation. At the Effective Time, the Articles of<br \/>\nIncorporation of the Surviving Corporation shall be amended in their entirety to<br \/>\nread as the Articles of Incorporation of Merger Sub, until thereafter changed or<br \/>\namended as provided therein or by applicable Law, except that Article I thereof<br \/>\nshall be amended to read as follows: &#8220;The name of the Corporation is Immunex<br \/>\nCorporation.&#8221; Such Articles shall not be inconsistent with Section 6.10.<\/p>\n<p>        (b) Bylaws. At the Effective Time, the Bylaws of Merger Sub, as in<br \/>\neffect immediately prior to the Effective Time, shall be the Bylaws of the<br \/>\nSurviving Corporation, until thereafter changed or amended as provided therein<br \/>\nor by applicable Law. Such Bylaws shall not be inconsistent with Section 6.10.<\/p>\n<p>        Section 1.5   Directors and Officers of the Surviving Corporation. The<br \/>\n                      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\ndirectors of Merger Sub immediately prior to the Effective Time shall be the<br \/>\ninitial directors of the Surviving Corporation, each to hold office in<br \/>\naccordance with the Articles of Incorporation and Bylaws of the Surviving<br \/>\nCorporation. The officers of Merger Sub immediately prior to the Effective Time<br \/>\nshall be the initial officers of the Surviving Corporation, each to hold office<br \/>\nin accordance with the Articles of Incorporation and Bylaws of the Surviving<br \/>\nCorporation.<\/p>\n<p>        Section 1.6   Directors of Parent. At or prior to the Effective Time,<br \/>\n                      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nthe Board of Directors of Parent shall take all action necessary so that,<br \/>\neffective immediately following the Effective Time, Edward V. Fritzky shall be<br \/>\nappointed to the Board of Directors of Parent. If at the Effective Time Parent<br \/>\nhas multiple classes of directors, Parent shall take all action reasonably<br \/>\nnecessary, subject to applicable Law, to appoint Mr. Fritzky to the class of<br \/>\ndirectors with the longest remaining term as of the Effective Time, provided,<br \/>\nthat Parent shall not be required to request that an incumbent director of<br \/>\nParent switch classes.<\/p>\n<p>                                   ARTICLE 2.<br \/>\n               CONVERSION OF SECURITIES; EXCHANGE OF CERTIFICATES<\/p>\n<p>        Section 2.1   Conversion of Securities. At the Effective Time, by virtue<br \/>\n                      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nof the Merger and without any action on the part of Merger Sub, the Company or<br \/>\nthe holders of any of the following securities:<\/p>\n<p>                                       2<\/p>\n<p>     (a) Conversion Generally. Each share of common stock, par value $0.01 per<br \/>\nshare, of the Company (&#8220;Company Common Stock&#8221;) issued and outstanding<br \/>\n                        &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nimmediately prior to the Effective Time (other than any shares of Company Common<br \/>\nStock to be canceled pursuant to Section 2.1(b) and dissenting shares referred<br \/>\nto in Section 2.1(e)) shall be converted, subject to Section 2.2(e), into the<br \/>\nright to receive (i) 0.440 (the &#8220;Exchange Ratio&#8221;) of a share of common stock,<br \/>\n                                 &#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\npar value $0.0001 per share (&#8220;Parent Common Stock&#8221;), of Parent (the &#8220;Common<br \/>\n                              &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-                    &#8212;&#8212;<br \/>\nStock Consideration&#8221;) and (ii) $4.50 in cash (the &#8220;Cash Consideration,&#8221; and<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-                                &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\ntogether with the Common Stock Consideration, the &#8220;Merger Consideration&#8221;). All<br \/>\n                                                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nsuch shares of Company Common Stock shall no longer be outstanding and shall<br \/>\nautomatically be canceled and retired and shall cease to exist, and each<br \/>\ncertificate previously representing any such shares shall thereafter represent<br \/>\nthe right to receive the Merger Consideration payable in respect of such shares<br \/>\nof Company Common Stock.<\/p>\n<p>     (b) Parent-Owned Shares. All shares of Company Common Stock owned by Parent<br \/>\nor any of its Subsidiaries shall be cancelled and retired and shall cease to<br \/>\nexist and no Merger Consideration or other consideration shall be delivered in<br \/>\nexchange therefor.<\/p>\n<p>     (c) Merger Sub. Each share of common stock of Merger Sub issued and<br \/>\noutstanding immediately prior to the Effective Time shall be converted into and<br \/>\nbe exchanged for one newly and validly issued, fully paid and nonassessable<br \/>\nshare of common stock of the Surviving Corporation.<\/p>\n<p>     (d) Change in Shares. If, between the date of this Agreement and the<br \/>\nEffective Time, the outstanding shares of Parent Common Stock or Company Common<br \/>\nStock shall have been changed into, or exchanged for, a different number of<br \/>\nshares or a different class, by reason of any stock dividend, subdivision,<br \/>\nreclassification, recapitalization, split, combination or exchange of shares,<br \/>\nthe Exchange Ratio and the Option Exchange Ratio shall be correspondingly<br \/>\nadjusted to provide the holders of Company Common Stock and Company Options the<br \/>\nsame economic effect as contemplated by this Agreement prior to such event.<\/p>\n<p>     (e) Dissenting Shares. Notwithstanding anything in this Agreement to the<br \/>\ncontrary, with respect to each share of Company Common Stock as to which the<br \/>\nholder thereof shall have properly complied with the provisions of Chapter<br \/>\n23B.13 of the WBCA as to dissenters&#8217; rights (each, a &#8220;Dissenting Share&#8221;), if<br \/>\n                                                      &#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nany, such holder shall be entitled to payment, solely from the Surviving<br \/>\nCorporation, of the appraisal value of the Dissenting Shares to the extent<br \/>\npermitted by and in accordance with the provisions of Chapter 23B.13 of the<br \/>\nWBCA; provided, however, that (i) if any holder of Dissenting Shares, under the<br \/>\ncircumstances permitted by and in accordance with the WBCA, affirmatively<br \/>\nwithdraws such holder&#8217;s demand for appraisal of such Dissenting Shares, (ii) if<br \/>\nany holder of Dissenting Shares fails to establish such holder&#8217;s entitlement to<br \/>\ndissenters&#8217; rights as provided in the WBCA or (iii) if any holder of Dissenting<br \/>\nShares takes or fails to take any action the consequence of which is that such<br \/>\nholder is not entitled to payment for such holder&#8217;s shares under the WBCA, such<br \/>\nholder or holders (as the case may be) shall forfeit the right to appraisal of<br \/>\nsuch shares of Company Common Stock and such shares of Company Common Stock<br \/>\nshall thereupon be deemed to have been converted, as of the Effective Time, into<br \/>\nand represent the right to receive the Merger Consideration payable in respect<br \/>\nof such shares of Company Common Stock. The Company shall give Parent prompt<br \/>\nnotice of any demands received by the Company for appraisal of shares of Company<br \/>\nCommon<\/p>\n<p>                                       3<\/p>\n<p>Stock, and Parent shall have the right to participate in all negotiations and<br \/>\nproceedings with respect to such demands. The Company shall not settle, make any<br \/>\npayments with respect to, or offer to settle, any claim with respect to<br \/>\nDissenting Shares without the written consent of Parent.<\/p>\n<p>                (f)   Associated Rights. References in this Agreement to Parent<br \/>\n Common Stock shall include, unless the context requires otherwise, the<br \/>\nassociated Preferred Share Purchase Rights issued pursuant to the Amended and<br \/>\nRestated Rights Agreement dated as of December 12, 2000 between Parent and<br \/>\nAmerican Stock Transfer and Trust Company, as Rights Agent (the &#8220;Rights Plan&#8221;).<br \/>\n                                                                 &#8212;&#8212;&#8212;&#8211;<\/p>\n<p>     Section 2.2 Exchange of Certificates.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>                (a)  Exchange Agent. As of the Effective Time, Parent shall<br \/>\ndeposit, or shall cause to be deposited, with American Stock Transfer and Trust<br \/>\nCompany or another bank or trust company designated by Parent and reasonably<br \/>\nsatisfactory to the Company (the &#8220;Exchange Agent&#8221;), for the benefit of the<br \/>\n                                  &#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nholders of shares of Company Common Stock, for exchange, in accordance with this<br \/>\nArticle 2, through the Exchange Agent, sufficient cash and certificates<br \/>\nrepresenting shares of Parent Common Stock to make all deliveries pursuant to<br \/>\nthis Article 2. Parent agrees to make available to the Exchange Agent, from time<br \/>\nto time as needed, cash sufficient to pay any dividends and other distributions<br \/>\npursuant to Section 2.2(c). The Exchange Agent shall, pursuant to irrevocable<br \/>\ninstructions, deliver the Merger Consideration contemplated to be paid for<br \/>\nshares of Company Common Stock pursuant to this Agreement out of the Exchange<br \/>\nFund. Except as contemplated by Sections 2.2(c) and 2.2(e) hereof, the Exchange<br \/>\nFund shall not be used for any other purpose. Any cash and certificates<br \/>\nrepresenting Parent Common Stock deposited with the Exchange Agent (including<br \/>\nthe proceeds from sales of Excess Shares in accordance with Section 2.2(e))<br \/>\nshall be referred to as the &#8220;Exchange Fund.&#8221;<br \/>\n                             &#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>                (b)  Exchange Procedures. Promptly after the Effective Time,<br \/>\nParent shall instruct the Exchange Agent to mail to each holder of record of a<br \/>\ncertificate or certificates which immediately prior to the Effective Time<br \/>\nrepresented outstanding shares of Company Common Stock (the &#8220;Certificates&#8221;) (i)<br \/>\n                                                             &#8212;&#8212;&#8212;&#8212;<br \/>\na letter of transmittal (which shall specify that delivery shall be effected,<br \/>\nand risk of loss and title to the Certificates shall pass, only upon proper<br \/>\ndelivery of the Certificates to the Exchange Agent and shall be in customary<br \/>\nform) and (ii) instructions for use in effecting the surrender of the<br \/>\nCertificates in exchange for the Merger Consideration payable in respect of the<br \/>\nshares of Company Common Stock represented by such Certificates. Upon surrender<br \/>\nof a Certificate for cancellation to the Exchange Agent together with such<br \/>\nletter of transmittal, properly completed and duly executed, and such other<br \/>\ndocuments as may be required pursuant to such instructions, the holder of such<br \/>\nCertificate shall be entitled to receive in exchange therefor the Merger<br \/>\nConsideration payable in respect of the shares of Company Common Stock<br \/>\nrepresented by such Certificate, cash in lieu of fractional shares of Parent<br \/>\nCommon Stock to which such holder is entitled pursuant to Section 2.2(e) and any<br \/>\ndividends or other distributions to which such holder is entitled pursuant to<br \/>\nSection 2.2(c), and the Certificate so surrendered shall forthwith be canceled.<br \/>\nNo interest shall be paid or accrued on any Cash Consideration, cash in lieu of<br \/>\nfractional shares or on any unpaid dividends and distributions payable to<br \/>\nholders of Certificates. In the event of a transfer of ownership of shares of<br \/>\nCompany Common Stock which is not registered in the transfer records of the<br \/>\nCompany, the Merger Consideration payable in respect of such shares of Company<br \/>\nCommon Stock may be paid to a<\/p>\n<p>                                       4<\/p>\n<p>transferee if the Certificate representing such shares of Company Common Stock<br \/>\nis presented to the Exchange Agent, accompanied by all documents required to<br \/>\nevidence and effect such transfer and by evidence that any applicable stock<br \/>\ntransfer Taxes have been paid. Until surrendered as contemplated by this Section<br \/>\n2.2, each Certificate shall be deemed at any time after the Effective Time to<br \/>\nrepresent only the right to receive upon such surrender the Merger Consideration<br \/>\npayable in respect of the shares of Company Common Stock represented by such<br \/>\nCertificate, cash in lieu of any fractional shares of Parent Common Stock to<br \/>\nwhich such holder is entitled pursuant to Section 2.2(e) and any dividends or<br \/>\nother distributions to which such holder is entitled pursuant to Section 2.2(c).<\/p>\n<p>     (c) Distributions with Respect to Unexchanged Shares of Parent Common<br \/>\nStock. No dividends or other distributions declared or made with respect to<br \/>\nshares of Parent Common Stock, with a record date after the Effective Time,<br \/>\nshall be paid to the holder of any unsurrendered Certificate, and no cash<br \/>\npayment in lieu of fractional shares of Parent Common Stock shall be paid to any<br \/>\nsuch holder pursuant to Section 2.2(e), unless and until the holder of such<br \/>\nCertificate shall surrender such Certificate. Subject to the effect of escheat,<br \/>\nTax or other applicable Laws, following surrender of any such Certificate, there<br \/>\nshall be paid to such holder of the certificates representing whole shares of<br \/>\nParent Common Stock issuable in exchange therefor, without interest, (i)<br \/>\npromptly, the amount of any cash due pursuant to Section 2.1 and cash payable in<br \/>\nlieu of fractional shares of Parent Common Stock to which such holder is<br \/>\nentitled pursuant to Section 2.2(e) and the amount of dividends or other<br \/>\ndistributions with a record date at or after the Effective Time theretofore paid<br \/>\nwith respect to such whole shares of Parent Common Stock and (ii) at the<br \/>\nappropriate payment date, the amount of dividends or other distributions, with a<br \/>\nrecord date at or after the Effective Time but prior to such surrender and a<br \/>\npayment date subsequent to such surrender, payable with respect to such whole<br \/>\nshares of Parent Common Stock.<\/p>\n<p>     (d) Further Rights in Company Common Stock. The Merger Consideration issued<br \/>\nupon conversion of a share of Company Common Stock in accordance with the terms<br \/>\nhereof (including any dividends or distributions pursuant to Section 2.2(c) or<br \/>\nSection 2.2(e)) shall be deemed to have been issued in full satisfaction of all<br \/>\nrights pertaining to such share of Company Common Stock.<\/p>\n<p>     (e) Fractional Shares. No certificates or scrip representing fractional<br \/>\nshares of Parent Common Stock shall be issued upon the surrender for exchange of<br \/>\nCertificates, no dividend or distribution with respect to Parent Common Stock<br \/>\nshall be payable on or with respect to any fractional share and such fractional<br \/>\nshare interests shall not entitle the owner thereof to any rights of a<br \/>\nstockholder of Parent.<\/p>\n<p>         (i) As promptly as practicable following the Effective Time, the<br \/>\nExchange Agent shall determine the closest number of whole shares of Parent<br \/>\nCommon Stock represented by the aggregate of the fractional share interests in<br \/>\nParent Common Stock to which all holders of Company Common Stock are entitled<br \/>\n(the &#8220;Excess Shares&#8221;). As soon after the Effective Time as practicable, the<br \/>\n      &#8212;&#8212;&#8212;&#8212;-<br \/>\nExchange Agent, as agent for such holders of Parent Common Stock, shall sell<br \/>\nthe Excess Shares at then prevailing prices on Nasdaq, all in the manner<br \/>\nprovided in this Section 2.2(e).<\/p>\n<p>                                       5<\/p>\n<p>         (ii)   The sale of the Excess Shares by the Exchange Agent shall be<br \/>\nexecuted on Nasdaq through one or more member firms of Nasdaq and shall be<br \/>\nexecuted in round lots to the extent practicable. Until the net proceeds of any<br \/>\nsuch sale or sales have been distributed to such holders of Company Common<br \/>\nStock, the Exchange Agent shall hold such proceeds in trust for such holders of<br \/>\nCompany Common Stock as part of the Exchange Fund. All commissions, transfer<br \/>\nTaxes and other out-of-pocket transaction costs of the Exchange Agent incurred<br \/>\nin connection with such sale or sales of Excess Shares shall be deducted from<br \/>\nthe Exchange Fund. In addition, the Exchange Agent&#8217;s compensation and expenses<br \/>\nin connection with such sale or sales shall be deducted from the Exchange Fund.<br \/>\nThe Exchange Agent shall determine the portion of such net proceeds to which<br \/>\neach holder of Company Common Stock shall be entitled, if any, by multiplying<br \/>\nthe amount of the aggregate net proceeds by a fraction the numerator of which is<br \/>\nthe amount of the fractional share interest to which such holder of Company<br \/>\nCommon Stock is entitled (after taking into account all shares of Parent Common<br \/>\nStock to be issued to such holder) and the denominator of which is the aggregate<br \/>\namount of fractional share interests to which all holders of Company Common<br \/>\nStock are entitled.<\/p>\n<p>         (iii)  As soon as practicable after the determination of the amount of<br \/>\ncash, if any, to be paid to holders of Company Common Stock with respect to any<br \/>\nfractional share interests, the Exchange Agent shall promptly pay such amounts<br \/>\nto such holders of Company Common Stock subject to and in accordance with the<br \/>\nterms of this Article 2.<\/p>\n<p>     (f) Termination of Exchange Fund. Any portion of the Exchange Fund which<br \/>\nremains undistributed to the holders of Company Common Stock for one year after<br \/>\nthe Effective Time shall be delivered to Parent, upon demand, and, from and<br \/>\nafter such delivery to Parent, any holders of Company Common Stock who have not<br \/>\ntheretofore complied with this Article 2 shall thereafter look only to Parent<br \/>\nfor the Merger Consideration payable in respect of such shares of Company Common<br \/>\nStock, any cash in lieu of fractional shares of Parent Common Stock to which<br \/>\nthey are entitled pursuant to Section 2.2(e) and any dividends or other<br \/>\ndistributions with respect to Parent Common Stock to which they are entitled<br \/>\npursuant to Section 2.2(c), in each case, without any interest thereon.<\/p>\n<p>     (g) No Liability. None of Parent, the Surviving Corporation or the Company<br \/>\nshall be liable to any holder of shares of Company Common Stock for any such<br \/>\nshares of Parent Common Stock (or dividends or distributions with respect<br \/>\nthereto) or cash from the Exchange Fund delivered to a public official pursuant<br \/>\nto any abandoned property, escheat or similar Law.<\/p>\n<p>     (h) Lost Certificates. If any Certificate shall have been lost, stolen or<br \/>\ndestroyed, upon the making of an affidavit of that fact by the person claiming<br \/>\nsuch Certificate to be lost, stolen or destroyed and, if required by Parent, the<br \/>\nposting by such person of a bond, in such reasonable amount as Parent may<br \/>\ndirect, as indemnity against any claim that may be made against it with respect<br \/>\nto such Certificate, the Exchange Agent shall pay in exchange for such lost,<br \/>\nstolen or destroyed Certificate the Merger Consideration payable in respect of<br \/>\nthe shares of Company Common Stock represented by such Certificate, any cash in<br \/>\nlieu of fractional shares of Parent Common Stock to which the holders thereof<br \/>\nare entitled pursuant to Section 2.2(e) and any dividends or other distributions<br \/>\nto which the holders thereof are entitled pursuant to Section 2.2(c), in each<br \/>\ncase, without any interest thereon.<\/p>\n<p>                                       6<\/p>\n<p>     (i) Withholding. Parent or the Exchange Agent shall be entitled to deduct<br \/>\nand withhold from the consideration otherwise payable pursuant to this Agreement<br \/>\nto any holder of Company Common Stock such amounts as Parent or the Exchange<br \/>\nAgent are required to deduct and withhold under the Code, or any Tax Law, with<br \/>\nrespect to the making of such payment. To the extent that amounts are so<br \/>\nwithheld by Parent or the Exchange Agent, such withheld amounts shall be treated<br \/>\nfor all purposes of this Agreement as having been paid to the holder of Company<br \/>\nCommon Stock in respect of whom such deduction and withholding was made by<br \/>\nParent or the Exchange Agent.<\/p>\n<p>     (j) Investment of Exchange Fund. The Exchange Agent shall invest any cash<br \/>\nincluded in the Exchange Fund, as directed by Parent, on a daily basis. Any<br \/>\ninterest and other income resulting from such investments shall be paid to<br \/>\nParent upon termination of the Exchange Fund pursuant to Section 2.2(f). In the<br \/>\nevent the cash in the Exchange Fund shall be insufficient to fully satisfy all<br \/>\nof the payment obligations to be made by the Exchange Agent hereunder, Parent<br \/>\nshall promptly deposit cash into the Exchange Fund in an amount which is equal<br \/>\nto the deficiency in the amount of cash required to fully satisfy such payment<br \/>\nobligations.<\/p>\n<p>     Section 2.3 Stock Transfer Books. At the Effective Time, the stock transfer<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nbooks of the Company shall be closed and thereafter, there shall be no further<br \/>\nregistration of transfers of shares of Company Common Stock theretofore<br \/>\noutstanding on the records of the Company. From and after the Effective Time,<br \/>\nthe holders of certificates representing shares of Company Common Stock<br \/>\noutstanding immediately prior to the Effective Time shall cease to have any<br \/>\nrights with respect to such shares of Company Common Stock except as otherwise<br \/>\nprovided herein or by Law. On or after the Effective Time, any Certificates<br \/>\npresented to the Exchange Agent or Parent for any reason shall be converted into<br \/>\nthe Merger Consideration payable in respect of the shares of Company Common<br \/>\nStock represented by such Certificates, any cash in lieu of fractional shares of<br \/>\nParent Common Stock to which the holders thereof are entitled pursuant to<br \/>\nSection 2.2(e) and any dividends or other distributions to which the holders<br \/>\nthereof are entitled pursuant to Section 2.2(c), without any interest thereon.<\/p>\n<p>     Section 2.4 Stock Options.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>     (a) At the Effective Time, each Company Option, other than Cancelled<br \/>\nCompany Options, then outstanding under any Company Stock Option Plan, whether<br \/>\nor not then exercisable, shall be converted into an option to purchase Parent<br \/>\nCommon Stock in accordance with this Section 2.4(a). Each Company Option so<br \/>\nconverted shall continue to have, and be subject to, the same terms and<br \/>\nconditions (including vesting schedule) as set forth in the applicable Company<br \/>\nStock Option Plan and any agreements thereunder immediately prior to the<br \/>\nEffective Time, except that, as of the Effective Time, (i) each Company Option<br \/>\nshall be exercisable (or shall become exercisable in accordance with its terms)<br \/>\nfor that number of whole shares of Parent Common Stock equal to the product of<br \/>\nthe number of shares that were issuable upon exercise of such Company Option<br \/>\nimmediately prior to the Effective Time multiplied by 0.52 (the &#8220;Option Exchange<br \/>\n                                                                 &#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nRatio&#8221;), rounded down to the nearest whole number of shares of Parent Common<br \/>\n&#8212;&#8211;<br \/>\nStock, (ii) the per share exercise price for the shares of Parent Common Stock<br \/>\nissuable upon exercise of such Company Option so converted shall be equal to the<br \/>\nquotient determined by dividing the exercise price per share of Company Common<br \/>\nStock at which such Company Option was exercisable immediately prior to the<br \/>\nEffective Time by the Option<\/p>\n<p>                                       7<\/p>\n<p>Exchange Ratio, rounded up to the nearest whole cent, and (iii) each Company<br \/>\nOption which (a) is outstanding as of the date of this Agreement, (b) remains<br \/>\noutstanding at the Effective Time, and (c) constitutes an Accelerated Company<br \/>\nOption immediately prior to the Effective Time, shall be fully vested and<br \/>\nexercisable as to all shares of Parent Common Stock subject thereto.<br \/>\nNotwithstanding the foregoing, the conversion of any Company Options which are<br \/>\n&#8220;incentive stock options,&#8221; within the meaning of Section 422 of the Code, into<br \/>\noptions to purchase Parent Common Stock shall be made so as not to constitute a<br \/>\n&#8220;modification&#8221; of such Company Options within the meaning of Section 424 of the<br \/>\nCode.<\/p>\n<p>     (b) At the Effective Time, each Cancelled Company Option then outstanding<br \/>\nunder any Company Stock Option Plan shall be cancelled, and in exchange<br \/>\ntherefor, shall be converted into an option (&#8220;Replacement Option&#8221;) to purchase<br \/>\n                                              &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nthat number of whole shares of Parent Common Stock equal to the product of the<br \/>\nnumber of shares subject to the related Cancelled Company Option multiplied by<br \/>\n0.4, rounded down to the nearest whole number of shares of Parent Common Stock,<br \/>\nwith an exercise price per share equal to the fair market value of a share of<br \/>\nParent Common Stock as of the date of grant of the Replacement Option (which<br \/>\nshall be as of the close of market on the date of the Effective Time)and<br \/>\notherwise subject to the terms and conditions (including the vesting schedule)<br \/>\nthat were applicable to the related Cancelled Company Option immediately prior<br \/>\nto the Effective Time, and neither the vesting nor exercisability of any<br \/>\nCancelled Company Option or Replacement Option shall be accelerated except as<br \/>\nprovided in the addendums to the Company Stock Option Plans.<\/p>\n<p>     Section 2.5   Employee Stock Purchase Plan. At the Effective Time, each<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\noutstanding purchase right under the Immunex Corporation 1999 Employee Stock<br \/>\nPurchase Plan (the &#8220;ESPP&#8221;) shall be assumed by Parent in such manner that Parent<br \/>\n                    &#8212;-<br \/>\nis a corporation &#8220;issuing or assuming a stock option in a transaction to which<br \/>\nSection 424(a) applies&#8221; within the meaning of the Code, and shall be converted<br \/>\ninto a right to purchase Parent Common Stock in accordance with this Section<br \/>\n2.5. Each purchase right so assumed and converted by Parent under this Agreement<br \/>\nwill continue to have, and be subject to, the same terms and conditions set<br \/>\nforth in the ESPP and the documents governing the outstanding purchase rights<br \/>\nunder the ESPP, immediately prior to the Effective Time, except that the<br \/>\npurchase price of shares of Parent Common Stock and the number of shares of<br \/>\nParent Common Stock to be issued upon the exercise of such purchase rights shall<br \/>\nbe adjusted in accordance with the Option Exchange Ratio.<\/p>\n<p>     Section 2.6   Employment Agreement.  Simultaneously with the execution of<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nthis Agreement, Parent has entered into an employment agreement with Edward V.<br \/>\nFritzky, which agreement shall become effective upon the Closing.<\/p>\n<p>     Section 2.7   AHP Agreements. Simultaneously with the execution of this<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nAgreement, each of that certain Stockholders&#8217; Rights Agreement by and among<br \/>\nParent, AHP, MDP Holdings, Inc. and Lederle Parenterals, Inc., that certain<br \/>\nAmended and Restated Promotion Agreement by and between Parent and AHP, and that<br \/>\ncertain Agreement Regarding Governance and Commercial Matters by and among<br \/>\nParent, AHP and American Cyanamid Company (collectively, the &#8220;AHP Agreements&#8221;)<br \/>\n                                                              &#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nhas been executed, which agreements shall become effective upon the Closing<br \/>\n(except that the Agreement Regarding Governance and Commercial Matters shall be<br \/>\neffective as of the date hereof).<\/p>\n<p>                                       8<\/p>\n<p>     Section 2.8   Role of Seattle and Rhode Island Following the Merger. Parent<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nintends to, following the Effective Time, (i) operate and grow the Company&#8217;s<br \/>\nSeattle, Washington facility as a major research and development center for<br \/>\nParent, (ii) maintain Seattle, Washington as the primary location for the team<br \/>\nof employees responsible for Enbrel, (iii) complete the Company&#8217;s Helix Project<br \/>\nresearch and technology center in Seattle, Washington, in order to consolidate<br \/>\nParent&#8217;s Seattle downtown operations to one campus, and (iv) operate and grow<br \/>\nthe West Greenwich, Rhode Island biotechnology manufacturing complex as a<br \/>\nlarge-scale manufacturing complex for biological products.<\/p>\n<p>                                   ARTICLE 3.<br \/>\n                  REPRESENTATIONS AND WARRANTIES OF THE COMPANY<\/p>\n<p>     Except as set forth in the corresponding section of the Disclosure Letter<br \/>\ndelivered by the Company to Parent prior to the execution of this Agreement (the<br \/>\n&#8220;Company Disclosure Letter&#8221;) (and subject to Section 9.13 hereof), the Company<br \/>\n &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nhereby represents and warrants to Parent as follows:<\/p>\n<p>     Section 3.1   Organization and Qualification; Subsidiaries. The Company is<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\na corporation duly organized and validly existing under the Laws of the State of<br \/>\nWashington and has paid all excise taxes required by the Washington Department<br \/>\nof Revenue. Each Subsidiary of the Company (collectively, the &#8220;Company<br \/>\n                                                               &#8212;&#8212;-<br \/>\nSubsidiaries&#8221;) has been duly organized and is validly existing under the Laws of<br \/>\n&#8212;&#8212;&#8212;&#8212;<br \/>\nthe State of Washington and has paid all excise taxes required by the Washington<br \/>\nDepartment of Revenue, except where the failure to be so organized, existing or<br \/>\nto have paid taxes would not, individually or in the aggregate, reasonably be<br \/>\nexpected to have a Company Material Adverse Effect. Each of the Company and the<br \/>\nCompany Subsidiaries has the requisite power and authority and all necessary<br \/>\ngovernmental approvals to own, lease and operate its properties and to carry on<br \/>\nits business as it is now being conducted, except where the failure to have such<br \/>\npower, authority and governmental approvals would not, individually or in the<br \/>\naggregate, reasonably be expected to have a Company Material Adverse Effect.<br \/>\nEach of the Company and the Company Subsidiaries is duly qualified or licensed<br \/>\nto do business, and is in good standing (but only with respect to jurisdictions<br \/>\nwhich recognize such concepts) in each jurisdiction where the character of the<br \/>\nproperties owned, leased or operated by it or the nature of its business makes<br \/>\nsuch qualification or licensing or good standing necessary, except for such<br \/>\nfailures to be so qualified or licensed and in good standing that would not,<br \/>\nindividually or in the aggregate, reasonably be expected to have a Company<br \/>\nMaterial Adverse Effect. Section 3.1 of the Company Disclosure Letter sets forth<br \/>\na true and complete list of all of the Company Subsidiaries. Except with respect<br \/>\nto securities of non-affiliates held for investment purposes which do not<br \/>\nconstitute more than a 5% percent interest in any such non-affiliate, neither<br \/>\nthe Company nor any Company Subsidiary holds an Equity Interest in any other<br \/>\nperson.<\/p>\n<p>     Section 3.2   Articles of Incorporation and Bylaws; Corporate Books and<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nRecords. The copies of the Company&#8217;s Articles of Incorporation (the &#8220;Company<br \/>\n&#8212;&#8212;-                                                              &#8212;&#8212;-<br \/>\nArticles&#8221;) and Bylaws (the &#8220;Company Bylaws&#8221;) that are listed as exhibits to the<br \/>\n&#8212;&#8212;&#8211;                    &#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nCompany&#8217;s Form 10-K for the year ended December 31, 2000 are complete and<br \/>\ncorrect copies thereof as in effect on the date hereof. The Company is not in<br \/>\nviolation of any of the provisions of the Company Articles or the Company Bylaws<br \/>\nas of the date hereof and will not, as of the Closing Date, be in violation of<br \/>\nany of the provisions of the Company Articles or Company Bylaws, as such Company<br \/>\nArticles and<\/p>\n<p>                                       9<\/p>\n<p>Company Bylaws may be amended between the date hereof and the Closing Date. True<br \/>\nand complete copies of all minute books of the Company since January 1, 1999<br \/>\nhave been made available by the Company to Parent.<\/p>\n<p>     Section 3.3   Capitalization.<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n<p>     (a) As of the date hereof, the authorized capital stock of the Company<br \/>\nconsists of 1,200,000,000 shares of Company Common Stock and 30,000,000 shares<br \/>\nof preferred stock, par value $0.01 per share (the &#8220;Company Preferred Stock&#8221;).<br \/>\n                                                    &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nAs of December 1, 2001, (i) 544,893,425 shares of Company Common Stock were<br \/>\nissued and outstanding, all of which were validly issued and fully paid,<br \/>\nnonassessable and, except pursuant to Sections 2.01 and 2.02 of the Governance<br \/>\nAgreement, free of preemptive rights, and (ii) 51,062,923 shares of Company<br \/>\nCommon Stock were issuable (and such number was reserved for issuance) upon<br \/>\nexercise of Company Options outstanding as of such date. As of the date hereof,<br \/>\nno shares of Company Preferred Stock are issued or outstanding.<\/p>\n<p>     (b) Except for outstanding Company Options, outstanding purchase rights<br \/>\nunder the ESPP and pursuant to Sections 2.01 and 2.02 of the Governance<br \/>\nAgreement, as of the date hereof, there are no options, warrants or other<br \/>\nrights, agreements, arrangements or commitments of any character to which the<br \/>\nCompany or any Company Subsidiary is a party or by which the Company or any<br \/>\nCompany Subsidiary is bound relating to the issued or unissued capital stock or<br \/>\nother Equity Interests of the Company or any Company Subsidiary, or obligating<br \/>\nthe Company or any Company Subsidiary to issue or sell any shares of its capital<br \/>\nstock or other Equity Interests. From December 1, 2001 to the date of this<br \/>\nAgreement, the Company has not issued any Equity Interests with respect to<br \/>\nCompany Common Stock, other than (x) Parent Common Stock issued upon exercise of<br \/>\nCompany Stock Options and (y) stock options issued to newly-hired employees in<br \/>\nthe ordinary course of business consistent with past practice. The Company has<br \/>\npreviously provided Parent with a true and complete list, as of December 15,<br \/>\n2001, of the prices at which outstanding Company Options may be exercised under<br \/>\nthe applicable Company Stock Option Plan, the number of Company Options<br \/>\noutstanding at each such price and the vesting schedule of the Company Options.<br \/>\nAll shares of Company Common Stock subject to issuance under the Company Stock<br \/>\nOption Plans, upon issuance prior to the Effective Time on the terms and<br \/>\nconditions specified in the instruments pursuant to which they are issuable,<br \/>\nwill be duly authorized, validly issued, fully paid, nonassessable and, except<br \/>\npursuant to Sections 2.01 and 2.02 of the Governance Agreement, free of<br \/>\npreemptive rights.<\/p>\n<p>     (c) Except as set forth in the Governance Agreement, there are no<br \/>\noutstanding contractual obligations of the Company or any Company Subsidiary (i)<br \/>\nrestricting the transfer of, (ii) affecting the voting rights of, (iii)<br \/>\nrequiring the repurchase, redemption or disposition of, or containing any right<br \/>\nof first refusal with respect to, (iv) requiring the registration for sale of,<br \/>\nor (v) granting any preemptive or antidilutive right with respect to, any<br \/>\nCompany Common Stock or any capital stock of, or other Equity Interests in, any<br \/>\nCompany Subsidiary. Each outstanding share of capital stock of each Company<br \/>\nSubsidiary is duly authorized, validly issued, fully paid, nonassessable and<br \/>\nfree of preemptive rights and is owned, beneficially and of record, by the<br \/>\nCompany or another Company Subsidiary free and clear of all security interests,<br \/>\nliens, claims, pledges, options, rights of first refusal, agreements,<br \/>\nlimitations on the Company&#8217;s or such other Company Subsidiary&#8217;s voting rights,<br \/>\ncharges and other encumbrances of any nature whatsoever.<\/p>\n<p>                                      10<\/p>\n<p>There are no outstanding contractual obligations of the Company or any Company<br \/>\nSubsidiary to make any loan to, or any equity or other investment (in the form<br \/>\nof a capital contribution or otherwise) in, any Company Subsidiary or any other<br \/>\nperson, other than guarantees by the Company of any indebtedness or other<br \/>\nobligations of any wholly-owned Company Subsidiary and other than loans made in<br \/>\nthe ordinary course consistent with past practice to employees of the Company<br \/>\nand its Subsidiaries. The Company has not adopted a shareholder rights plan.<\/p>\n<p>     Section 3.4   Authority.<br \/>\n                   &#8212;&#8212;&#8212;<\/p>\n<p>     (a) The Company has all necessary corporate power and authority to execute<br \/>\nand deliver this Agreement, to perform its obligations hereunder and to<br \/>\nconsummate the transactions contemplated by this Agreement. The execution and<br \/>\ndelivery of this Agreement by the Company and the consummation by the Company of<br \/>\nsuch transactions have been duly and validly authorized by all necessary<br \/>\ncorporate action and no other corporate proceedings on the part of the Company<br \/>\nand no shareholder votes are necessary to authorize this Agreement or to<br \/>\nconsummate such transactions other than, with respect to the Merger, as provided<br \/>\nin Section 3.21. The Board of Directors of the Company, by resolutions adopted<br \/>\nby vote of at least a majority of the Board of Directors of the Company at a<br \/>\nmeeting duly called and held at which a quorum was present and acting<br \/>\nthroughout, has duly (i) adopted this Agreement and the transactions<br \/>\ncontemplated hereby, which adoption has not been rescinded or modified, (ii)<br \/>\nresolved (subject to Section 6.4) to recommend this Agreement and the Merger to<br \/>\nits shareholders for approval and (iii) directed that this Agreement be<br \/>\nsubmitted to its shareholders for consideration in accordance with this<br \/>\nAgreement. All necessary approvals under the Governance Agreement have been<br \/>\nobtained with respect to the execution and performance by the Company of this<br \/>\nAgreement and the consummation of the Merger. No approval by the Company is<br \/>\nnecessary under the Governance Agreement for the execution and performance by<br \/>\nAHP, MDP Holdings, Inc. and Lederle Parenterals, Inc. of the Voting Agreement.<br \/>\nThe Company has waived its rights with respect to the Merger under Section<br \/>\n5.1(d) of the Governance Agreement. This Agreement has been duly and validly<br \/>\nexecuted and delivered by the Company and constitutes the legal, valid and<br \/>\nbinding obligation of the Company, enforceable against the Company in accordance<br \/>\nwith its terms.<\/p>\n<p>     (b) A majority of the Board of Directors of the Company has approved this<br \/>\nAgreement and the Voting Agreement and the transactions contemplated hereby and<br \/>\nthereby for purposes of Chapter 23B.19 of the WBCA such that the restrictions<br \/>\nset forth in Section 23B.19.040 of the WBCA are not applicable to this Agreement<br \/>\nor the Voting Agreement or the consummation of the transactions contemplated<br \/>\nhereby and thereby, or to the Surviving Corporation or Parent and their<br \/>\nAffiliates or transferees following the Merger. No other State of Washington<br \/>\ntakeover statute or similar statute or regulation is applicable to the Merger.<\/p>\n<p>     Section 3.5   No Conflict; Required Filings and Consents.<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>     (a) The execution and delivery of this Agreement by the Company do not, and<br \/>\nthe performance of this Agreement by the Company will not, (i) conflict with or<br \/>\nviolate any provision of the Company Articles, the Company Bylaws, any<br \/>\nequivalent organizational documents of any Company Subsidiary or the Governance<br \/>\nAgreement (assuming the Company Shareholder Approval is obtained), (ii) assuming<br \/>\nthat all consents, approvals, authorizations and<\/p>\n<p>                                       11<\/p>\n<p>permits described in Section 3.5(b) have been obtained and all filings and<br \/>\nnotifications described in Section 3.5(b) have been made and any waiting periods<br \/>\nthereunder have terminated or expired, conflict with or violate any Law<br \/>\napplicable to the Company or any Company Subsidiary or by which any property or<br \/>\nasset of the Company or any Company Subsidiary is bound or affected or (iii)<br \/>\nrequire any consent or approval under, result in any breach of, any loss of any<br \/>\nbenefit under or constitute a change of control or default (or an event which<br \/>\nwith notice or lapse of time or both would become a default) under, or give to<br \/>\nothers any right of termination, vesting, amendment, acceleration or<br \/>\ncancellation of, or result in the creation of a lien or other encumbrance on any<br \/>\nproperty or asset of the Company or any Company Subsidiary pursuant to, any<br \/>\nContract, Company Permit or other instrument or obligation, except, with respect<br \/>\nto clauses (ii) and (iii), for any such conflicts, violations, breaches,<br \/>\ndefaults or other occurrences which would not, individually or in the aggregate,<br \/>\nreasonably be expected to (x) have a Company Material Adverse Effect or (y)<br \/>\nprevent or materially delay the performance under this Agreement by the Company.<\/p>\n<p>     (b) The execution and delivery of this Agreement by the Company do not, and<br \/>\nthe performance of this Agreement by the Company will not, require any consent,<br \/>\napproval, authorization or permit of, or filing with or notification to, any<br \/>\ndomestic or foreign Governmental Entity or any other person, except (i) under<br \/>\nthe Exchange Act, the Securities Act, any applicable Blue Sky Law, the rules and<br \/>\nregulations of Nasdaq, the HSR Act, foreign or supranational antitrust and<br \/>\ncompetition Laws and the filing and recordation of the Articles of Merger as<br \/>\nrequired by the WBCA and (ii) where failure to obtain such consents, approvals,<br \/>\nauthorizations or permits, or to make such filings or notifications to a person<br \/>\nother than a Governmental Entity, would not, individually or in the aggregate,<br \/>\nreasonably be expected to (x) have a Company Material Adverse Effect or (y)<br \/>\nprevent or materially delay the performance of this Agreement by the Company.<\/p>\n<p>     Section 3.6   Permits; Compliance With Law. Each of the Company and the<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nCompany Subsidiaries is in possession of all authorizations, licenses, permits,<br \/>\ncertificates, approvals and clearances, and has submitted notices to, all<br \/>\nGovernmental Entities (including all authorizations under the Federal Food, Drug<br \/>\nand Cosmetic Act of 1938, as amended (the &#8220;FDCA&#8221;) and the regulations of the<br \/>\n                                           &#8212;-<br \/>\nUnited States Food and Drug Administration (the &#8220;FDA&#8221;) promulgated thereunder)<br \/>\n                                                 &#8212;<br \/>\nnecessary for the Company or any Company Subsidiary to own, lease and operate<br \/>\nits properties or other assets and to carry on their respective businesses in<br \/>\nthe manner described in the Company SEC Filings filed prior to the date hereof<br \/>\nand as it is being conducted as of the date hereof (the &#8220;Company Permits&#8221;), and<br \/>\n                                                         &#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nall such Company Permits are valid, and in full force and effect, except where<br \/>\nthe failure to have, or the suspension or cancellation of, or failure to be<br \/>\nvalid or in full force and effect of, any of the Company Permits would not,<br \/>\nindividually or in the aggregate, reasonably be expected to have a Company<br \/>\nMaterial Adverse Effect. Neither the Company nor any Company Subsidiary is in<br \/>\nconflict with, or in default or violation of, (i) any Law applicable to the<br \/>\nCompany or any Company Subsidiary or by which any property or asset of the<br \/>\nCompany or any Company Subsidiary is bound or affected or (ii) any Company<br \/>\nPermits, except, with respect to clauses (i) and (ii), for any such conflicts,<br \/>\ndefaults or violations that would not, individually or in the aggregate,<br \/>\nreasonably be expected to have a Company Material Adverse Effect.<\/p>\n<p>                                       12<\/p>\n<p>     Section 3.7 SEC Filings; Financial Statements.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>     (a) The Company has timely filed all registration statements, prospectuses,<br \/>\nforms, reports, definitive proxy statements, schedules and documents required to<br \/>\nbe filed by it under the Securities Act or the Exchange Act, as the case may be,<br \/>\nsince January 1, 1998 (collectively, the &#8220;Company SEC Filings&#8221;). Each Company<br \/>\n                                          &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nSEC Filing (i) as of its date, complied in all material respects with the<br \/>\nrequirements of the Securities Act or the Exchange Act, as the case may be, and<br \/>\n(ii) did not, at the time it was filed, contain any untrue statement of a<br \/>\nmaterial fact or omit to state a material fact required to be stated therein or<br \/>\nnecessary in order to make the statements made therein, in the light of the<br \/>\ncircumstances under which they were made, not misleading. As of the date of this<br \/>\nAgreement, no Company Subsidiary is subject to the periodic reporting<br \/>\nrequirements of the Exchange Act.<\/p>\n<p>      (b) Each of the consolidated financial statements (including, in each<br \/>\ncase, any notes thereto) contained in the Company SEC Filings was prepared in<br \/>\nall material respects in accordance with GAAP applied (except as may be<br \/>\nindicated in the notes thereto and, in the case of unaudited quarterly financial<br \/>\nstatements, as permitted by Form 10-Q under the Exchange Act) on a consistent<br \/>\nbasis throughout the periods indicated (except as may be indicated in the notes<br \/>\nthereto), and each presented fairly the consolidated financial position, results<br \/>\nof operations and cash flows of the Company and the consolidated Company<br \/>\nSubsidiaries as of the respective dates thereof and for the respective periods<br \/>\nindicated therein (subject, in the case of unaudited statements, to normal and<br \/>\nrecurring year-end adjustments which did not and would not, individually or in<br \/>\nthe aggregate, reasonably be expected to have a Company Material Adverse<br \/>\nEffect). The books and records of the Company and the Company Subsidiaries have<br \/>\nbeen, and are being, maintained in all material respects in accordance with GAAP<br \/>\nand any other applicable legal and accounting requirements.<\/p>\n<p>     (c) Except as and to the extent set forth on the consolidated balance sheet<br \/>\nof the Company and the consolidated Company Subsidiaries as of December 31, 2000<br \/>\nincluded in the Company&#8217;s Form 10-K for the year ended December 31, 2000,<br \/>\nincluding the notes thereto (the &#8220;Company Form 10-K&#8221;), neither the Company nor<br \/>\n                                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nany consolidated Company Subsidiary has any liabilities or obligations of any<br \/>\nnature (whether accrued, absolute, contingent or otherwise) that would be<br \/>\nrequired to be reflected on a balance sheet or in notes thereto prepared in<br \/>\naccordance with GAAP, except for (i) liabilities or obligations incurred in the<br \/>\nordinary course of business consistent with past practice since December 31,<br \/>\n2000 and (ii) liabilities and obligations incurred in connection with this<br \/>\nAgreement and the transactions contemplated hereby that would not, individually<br \/>\nor in the aggregate, reasonably be expected to have a Company Material Adverse<br \/>\nEffect.<\/p>\n<p>     (d) As of the date hereof, no &#8220;material contract&#8221; (as such term is defined<br \/>\nin Item 601(b)(10) of Regulation S-K of the SEC) filed as an exhibit to the<br \/>\nCompany Form 10-K has been amended or modified, except for such amendments or<br \/>\nmodifications which have been filed as an exhibit to a subsequently dated<br \/>\nCompany SEC Filing or are not required to be filed with the SEC.<\/p>\n<p>     Section 3.8  Absence of Certain Changes or Events.  Since December 31,<br \/>\n                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\n2000, except as disclosed in the Company Form 10-K or in Company SEC Filings<br \/>\nsince December 31,<\/p>\n<p>                                       13<\/p>\n<p>2000 through to the date of this Agreement, including the notes thereto, and<br \/>\nexcept as specifically contemplated by, or as disclosed in, this Agreement, the<br \/>\nCompany and the Company Subsidiaries have conducted their businesses in the<br \/>\nordinary course consistent with past practice and, since such date, there has<br \/>\nnot been (a) an event or development that would, individually or in the<br \/>\naggregate, reasonably be expected to have a Company Material Adverse Effect or<br \/>\n(b) any event or development that would, individually or in the aggregate,<br \/>\nreasonably be expected to prevent or materially delay the performance of this<br \/>\nAgreement by the Company.<\/p>\n<p>Section 3.9   Employee Benefit Plans.<br \/>\n              &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>     (a) Section 3.9(a) of the Company Disclosure Letter sets forth a true and<br \/>\ncomplete list of each &#8220;employee benefit plan&#8221; as defined in Section 3(3) of<br \/>\nERISA and any other material plan, policy, program, practice, agreement,<br \/>\nunderstanding or arrangement providing compensation or other benefits to any<br \/>\ncurrent or former director, officer, employee or consultant (or to any dependent<br \/>\nor beneficiary thereof) of the Company or any ERISA Affiliate, which are now, or<br \/>\nwith respect to any plan intended to be qualified under 401(a) of the Code, were<br \/>\nwithin the past 6 years, maintained, sponsored or contributed to by the Company<br \/>\nor any ERISA Affiliate, or under which the Company or any ERISA Affiliate has<br \/>\nany obligation or liability, whether actual or contingent, including, without<br \/>\nlimitation, all material incentive, bonus, deferred compensation, vacation,<br \/>\nholiday, cafeteria, medical, disability, stock purchase, stock option, stock<br \/>\nappreciation, phantom stock, restricted stock or other stock-based compensation<br \/>\nplans, policies, programs, practices or arrangements. Each &#8220;employee benefit<br \/>\nplan&#8221; as defined in Section 3(3) of ERISA and each other material plan, policy,<br \/>\nprogram, practice, agreement, understanding or arrangement providing<br \/>\ncompensation or other benefits to any current or former director, officer,<br \/>\nemployee or consultant (or to any dependent or beneficiary thereof) of the<br \/>\nCompany or any ERISA Affiliate, which are now, or were within the past 6 years,<br \/>\nmaintained, sponsored or contributed to by the Company or any ERISA Affiliate,<br \/>\nor under which the Company or any ERISA Affiliate has any obligation or<br \/>\nliability, whether actual or contingent, including, without limitation, all<br \/>\nmaterial incentive, bonus, deferred compensation, vacation, holiday, cafeteria,<br \/>\nmedical, disability, stock purchase, stock option, stock appreciation, phantom<br \/>\nstock, restricted stock or other stock-based compensation plans, policies,<br \/>\nprograms, practices or arrangements is hereinafter referred to as a &#8220;Company<br \/>\n                                                                     &#8212;&#8212;-<br \/>\nBenefit Plan&#8221;. Neither the Company, nor to the Knowledge of the Company, any<br \/>\n&#8212;&#8212;&#8212;&#8212;<br \/>\nother person, has any express or implied commitment, whether legally enforceable<br \/>\nor not, to modify, change or terminate any Company Benefit Plan, other than with<br \/>\nrespect to a modification, change or termination required by ERISA or the Code.<br \/>\nThe Company has delivered or made available to Parent true, correct and complete<br \/>\ncopies of all Company Benefit Plans (or, if not so delivered, has delivered or<br \/>\nmade available to Parent a written summary of their material terms), and, with<br \/>\nrespect thereto, all amendments, trust agreements, insurance Contracts, other<br \/>\nfunding vehicles, determination letters issued by the United States Internal<br \/>\nRevenue Service (the &#8220;IRS&#8221;), the most recent annual reports (Form 5500 series)<br \/>\n                      &#8212;<br \/>\nfiled with the IRS, and the most recent actuarial report or other financial<br \/>\nstatement relating to such Company Benefit Plan.<\/p>\n<p>(b) Each Company Benefit Plan has been administered in all material respects in<br \/>\naccordance with its terms and all applicable Laws, including ERISA and the Code,<br \/>\nand contributions required to be made under the terms of any of the Company<br \/>\nBenefit Plans as of the date of this Agreement have been timely made. Except as<br \/>\nwould not, individually or in the<\/p>\n<p>                                       14<\/p>\n<p>aggregate, reasonably be expected to have a Company Material Adverse Effect, (i)<br \/>\nwith respect to the Company Benefit Plans, no event has occurred and, to the<br \/>\nKnowledge of the Company, there exists no condition or set of circumstances in<br \/>\nconnection with which the Company could be subject to any material liability<br \/>\n(other than for routine benefit liabilities) under the terms of, or with respect<br \/>\nto, such Company Benefit Plans, ERISA, the Code or any other applicable Law, and<br \/>\n(ii) neither the Company nor any ERISA Affiliate has any liability under ERISA<br \/>\nSection 502.<\/p>\n<p>     (c) Each Company Benefit Plan that is intended to be qualified under<br \/>\nSection 401(a) of the Code has obtained a favorable determination letter from<br \/>\nthe IRS that the Company Benefit Plan is so qualified and all related trusts are<br \/>\nexempt from U.S. federal income taxation under Section 501(a) of the Code, and,<br \/>\nto the Knowledge of the Company, nothing has occurred, whether by action or by<br \/>\nfailure to act, which would cause the loss of such qualification or exemption.<br \/>\nExcept as would not reasonably be expected to result in material liability to<br \/>\nthe Company or a Company ERISA Affiliate, (i) to the knowledge of the Company<br \/>\nthere has been no prohibited transaction (within the meaning of Section 406 of<br \/>\nERISA or Section 4975 of the Code and other than a transaction that is exempt<br \/>\nunder a statutory or administrative exemption) with respect to any Company<br \/>\nBenefit Plan, (ii) no suit, administrative proceeding, action or other<br \/>\nlitigation has been brought, or to the Knowledge of the Company is threatened,<br \/>\nagainst or with respect to any such Company Benefit Plan, including any audit or<br \/>\ninquiry by the IRS or United States Department of Labor (other than routine<br \/>\nbenefits claims), (iii) none of the assets of the Company or any Company ERISA<br \/>\nAffiliate is, or may reasonably be expected to become, the subject of any lien<br \/>\narising under ERISA or Section 412(n) of the Code, (iv) all Tax, annual<br \/>\nreporting and other governmental filings required by ERISA and the Code have<br \/>\nbeen timely filed with the appropriate Governmental Entity and all notices and<br \/>\ndisclosures have been timely provided to participants, (v) all contributions and<br \/>\npayments to each Company Benefit Plan are deductible under Code Sections 162 or<br \/>\n404, and (vi) no excise Tax could be imposed upon the Company under Chapter 43<br \/>\nof the Code.<\/p>\n<p>     (d) Neither the Company nor any of its ERISA Affiliates sponsors,<br \/>\nmaintains, contributes to or has an obligation to contribute to, or has<br \/>\nsponsored, maintained, contributed to or had an obligation to contribute to, any<br \/>\n&#8220;employee pension benefit plan&#8221; (as defined in Section 3(2) of ERISA) that is<br \/>\nsubject to Title IV of ERISA or Section 412 of the Code, or any &#8220;multiemployer<br \/>\nplan&#8221; as defined in Section 3(37) of ERISA.<\/p>\n<p>     (e) No amount that could be received (whether in cash or property or the<br \/>\nvesting of property), in connection with the consummation of the transactions<br \/>\ncontemplated by this Agreement, by any employee, officer or director of the<br \/>\nCompany or any of its Subsidiaries who is a &#8220;disqualified individual&#8221; (as such<br \/>\nterm is defined in proposed Treasury Regulation Section 1.280G-1) under any<br \/>\nCompany Benefit Plan or otherwise are reasonably likely to be characterized as<br \/>\nan &#8220;excess parachute payment&#8221; (as defined in Section 280G(b)(1) of the Code).<\/p>\n<p>     (f) Except as required by Law, no Company Benefit Plan provides any of the<br \/>\nfollowing retiree or post-employment benefits to any person: medical, disability<br \/>\nor life insurance benefits. The Company and each ERISA Affiliate are in<br \/>\ncompliance with (i) the requirements of the applicable health care continuation<br \/>\nand notice provisions of the Consolidated Omnibus Budget Reconciliation Act of<br \/>\n1985, as amended, and the regulations (including proposed regulations)<br \/>\nthereunder and any similar state Law and (ii) the applicable requirements of the<\/p>\n<p>                                       15<\/p>\n<p>Health Insurance Portability and Accountability Act of 1996, as amended, and the<br \/>\nregulations (including the proposed regulations) thereunder, except as would not<br \/>\nbe reasonably expected to result in material liability to the Company or a<br \/>\nCompany ERISA Affiliate.<\/p>\n<p>     (g) Neither the Company nor any of its Subsidiaries, sponsors, contributes<br \/>\nto or has any liability with respect to any employee benefit plan, program or<br \/>\narrangement that provides benefits to non-resident aliens with no United States<br \/>\nsource income outside of the United States.<\/p>\n<p>     (h) The Company has delivered to Parent accurate W-2 information for the<br \/>\nexecutive officers of the Company for the 1997, 1998, 1999 and 2000 calendar<br \/>\nyears.<\/p>\n<p>     Section 3.10  Labor and Other Employment Matters.<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>     (a) Except as would not, individually or in the aggregate, reasonably be<br \/>\nexpected to have a Company Material Adverse Effect, (i) no work stoppage or<br \/>\nlabor strike against the Company or any Company Subsidiary by employees is<br \/>\npending or threatened, (ii) neither the Company nor any Company Subsidiary is<br \/>\ndelinquent in payments to any of its employees for any wages, salaries,<br \/>\ncommissions, bonuses or other direct compensation for any services performed for<br \/>\nit or amounts required to be reimbursed to such employees, (iii) the Company and<br \/>\neach of the Company Subsidiaries are in compliance with all applicable Laws<br \/>\nrespecting labor, employment, fair employment practices, terms and conditions of<br \/>\nemployment, workers&#8221; compensation, occupational safety, plant closings, and wage<br \/>\nand hours, (iv) the Company and each Company Subsidiary has withheld all amounts<br \/>\nrequired by Law or by agreement to be withheld from the wages, salaries, and<br \/>\nother payments to employees; and is not liable for any arrears of wages or any<br \/>\nTaxes or any penalty for failure to comply with any of the foregoing, (v)<br \/>\nneither the Company nor any Company Subsidiary is liable for any payment to any<br \/>\ntrust or other fund or to any Governmental Entity, with respect to unemployment<br \/>\ncompensation benefits, social security or other benefits or obligations for<br \/>\nemployees (other than routine payments to be made in the ordinary course of<br \/>\nbusiness consistent with past practice), (vi) there are no material pending<br \/>\nclaims against the Company or any Company Subsidiary under any workers&#8217;<br \/>\ncompensation plan or policy or for long term disability and (vii) there are no<br \/>\nmaterial controversies pending or, to the Knowledge of the Company, threatened,<br \/>\nbetween the Company or any Company Subsidiary and any of their respective<br \/>\ncurrent or former employees, which controversies have or could reasonably be<br \/>\nexpected to result in an action, suit, proceeding, claim, arbitration or<br \/>\ninvestigation before any Governmental Entity. To the Company&#8217;s Knowledge, as of<br \/>\nthe date hereof, no employees of the Company or any Company Subsidiary are in<br \/>\nany material respect in violation of any term of any employment Contract,<br \/>\nnon-disclosure agreement, noncompetition agreement, or any restrictive covenant<br \/>\nto a former employer relating to the right of any such employee to be employed<br \/>\nby the Company or any Company Subsidiary because of the nature of the business<br \/>\nconducted or presently proposed to be conducted by the Company or such Company<br \/>\nSubsidiary or to the use of trade secrets or proprietary information of others.<br \/>\nAs of the date hereof, no employee of the Company or any Company Subsidiary, at<br \/>\nthe officer level or above, has given notice to the Company or any Company<br \/>\nSubsidiary that any such employee intends to terminate his or her employment<br \/>\nwith the Company or any Company Subsidiary.<\/p>\n<p>                                       16<\/p>\n<p>     (b) Neither the Company nor any Company Subsidiary is a party to or<br \/>\notherwise bound by any collective bargaining Contract with a labor union or<br \/>\nlabor organization, nor is any such Contract presently being negotiated. As of<br \/>\nthe date hereof, there has not been since January 1, 1998 a representation<br \/>\nquestion respecting any of the employees of the Company or any Company<br \/>\nSubsidiary and, to the Knowledge of the Company, there are no campaigns being<br \/>\nconducted to solicit cards from employees of the Company or any Company<br \/>\nSubsidiary to authorize representation by any labor organization.<\/p>\n<p>     (c) The Company has identified in Section 3.10(c) of the Company Disclosure<br \/>\nLetter and has made available to Parent true and complete copies of (i) all<br \/>\nseverance and employment agreements with directors, officers or employees of or<br \/>\nconsultants to the Company or any Company Subsidiary, (ii) all severance<br \/>\nprograms and policies of each of the Company and each Company Subsidiary with or<br \/>\nrelating to its employees, and (iii) all plans, programs, agreements and other<br \/>\narrangements of each of the Company and each Company Subsidiary with or relating<br \/>\nto its directors, officers, employees or consultants which contain change in<br \/>\ncontrol provisions. Neither the execution and delivery of this Agreement or<br \/>\nother related agreements, nor the consummation of the transactions contemplated<br \/>\nhereby or thereby will (either alone or in conjunction with any other event,<br \/>\nsuch as termination of employment) (i) result in any payment (including, without<br \/>\nlimitation, severance, unemployment compensation, parachute or otherwise)<br \/>\nbecoming due to any director or any employee of the Company or any Company<br \/>\nSubsidiary or Affiliate from the Company or any Company Subsidiary or Affiliate<br \/>\nunder any Company Benefit Plan or otherwise, (ii) significantly increase any<br \/>\nbenefits otherwise payable under any Company Benefit Plan or (iii) result in any<br \/>\nacceleration of the time of payment or vesting of any benefits.<\/p>\n<p>     Section 3.11  Tax Treatment. None of the Company, any Company Subsidiary<br \/>\n                   &#8212;&#8212;&#8212;&#8212;-<br \/>\nnor any of the Company&#8217;s Affiliates has taken or agreed to take any action that<br \/>\nwould prevent the Merger from qualifying as a reorganization within the meaning<br \/>\nof Section 368(a) of the Code. The Company is not aware of any agreement, plan<br \/>\nor other circumstance that would prevent the Merger from qualifying as a<br \/>\nreorganization within the meaning of Section 368(a) of the Code.<\/p>\n<p>     Section 3.12   Contracts. Except as filed as exhibits to the Company SEC<br \/>\n                    &#8212;&#8212;&#8212;<br \/>\nFilings filed prior to the date of this Agreement, or as disclosed in Section<br \/>\n3.12 of the Company Disclosure Letter, neither the Company nor any Company<br \/>\nSubsidiary is a party to or bound by any Contract that (i) is a &#8220;material<br \/>\ncontract&#8221; (as such term is defined in Item 601(b)(10) of Regulation S-K of the<br \/>\nSEC), (ii) relates to the co-promotion or distribution of Enbrel, the<br \/>\nmanufacturing and supply by third parties of Enbrel, the out-license of Company<br \/>\nIntellectual Property relating to Enbrel to third parties pursuant to which the<br \/>\nCompany currently receives royalties, or the in-license of intellectual property<br \/>\nrelating to Enbrel from third parties pursuant to which the Company currently<br \/>\npays royalties or (iii) limits or otherwise restricts the Company or any Company<br \/>\nSubsidiary or that would, after the Effective Time, limit or restrict Parent or<br \/>\nany of its Subsidiaries (including the Surviving Corporation and its<br \/>\nSubsidiaries) or any successor thereto, from engaging or competing in any line<br \/>\nof business or in any geographic area, which Contracts would be material to<br \/>\nParent and its Subsidiaries (determined after giving effect to the Merger). Each<br \/>\nContract of the type described in this Section 3.12, whether or not set forth in<br \/>\nSection 3.12 of the Company Disclosure Letter, is referred to herein as a<br \/>\n&#8220;Company Material Contract.&#8221; Each Company Material Contract is valid and binding<br \/>\n &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\non the Company or a<\/p>\n<p>                                       17<\/p>\n<p>Company Subsidiary party thereto and, to the Company&#8217;s Knowledge, each other<br \/>\nparty thereto, and is in full force and effect, and the Company and each of the<br \/>\nCompany Subsidiaries have performed in all material respects all obligations<br \/>\nrequired to be performed by them to the date hereof under each Company Material<br \/>\nContract and, to the Company&#8217;s Knowledge, each other party to each Company<br \/>\nMaterial Contract has performed in all material respects all obligations<br \/>\nrequired to be performed by it under such Company Material Contract, except, in<br \/>\neach case, as would not, individually or in the aggregate, reasonably be<br \/>\nexpected to have a Company Material Adverse Effect. Neither the Company nor any<br \/>\nCompany Subsidiary knows of, or has received notice of, any violation or default<br \/>\nunder (or any condition which with the passage of time or the giving of notice<br \/>\nwould cause such a violation of or default under) any Company Material Contract<br \/>\nor any other Contract to which it is a party or by which it or any of its<br \/>\nproperties or assets is bound, except for violations or defaults that would not,<br \/>\nindividually or in the aggregate, reasonably be expected to have a Company<br \/>\nMaterial Adverse Effect.<\/p>\n<p>     Section 3.13  Litigation. Except as and to the extent disclosed in the<br \/>\n                   &#8212;&#8212;&#8212;-<br \/>\nCompany SEC Filings, including the notes thereto, filed prior to the date of<br \/>\nthis Agreement or would not, individually or in the aggregate, reasonably be<br \/>\nexpected to have a Company Material Adverse Effect, (i) there is no suit, claim,<br \/>\naction, proceeding or investigation pending or, to the Knowledge of the Company,<br \/>\nthreatened in writing against the Company or any Company Subsidiary or for which<br \/>\nthe Company or any Company Subsidiary is obligated to indemnify a third party<br \/>\nthat, as of the date hereof, relates to Enbrel, and (ii) neither the Company nor<br \/>\nany Company Subsidiary is subject to any outstanding and unsatisfied order,<br \/>\nwrit, injunction, decree or arbitration ruling, award or other finding. There is<br \/>\nno suit, claim, action, proceeding or investigation pending or, to the Knowledge<br \/>\nof the Company, threatened in writing against the Company or any Company<br \/>\nSubsidiary that, as of the date hereof, challenges the validity or propriety, or<br \/>\nseeks to prevent consummation of, the Merger or any other transaction<br \/>\ncontemplated by this Agreement.<\/p>\n<p>     Section 3.14  Environmental Matters. Except as disclosed in the Company<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nForm 10-K or in Company SEC Filings, including the notes thereto, since December<br \/>\n31, 2000 through to the date of this Agreement or would not, individually or in<br \/>\nthe aggregate, reasonably be expected to have a Company Material Adverse Effect:<\/p>\n<p>     (a) The Company and the Company Subsidiaries (i) are in compliance with<br \/>\nall, and are not subject to any liability, in each case with respect to any,<br \/>\napplicable Environmental Laws, (ii) hold or have applied for all Environmental<br \/>\nPermits necessary to conduct their current operations and (iii) are in<br \/>\ncompliance with their respective Environmental Permits.<\/p>\n<p>     (b) Neither the Company nor any Company Subsidiary has received any written<br \/>\nnotice, demand, letter, claim or request for information alleging that the<br \/>\nCompany or any Company Subsidiary may be in violation of, or liable under, any<br \/>\nEnvironmental Law.<\/p>\n<p>     (c) Neither the Company nor any Company Subsidiary (i) has entered into or<br \/>\nagreed to any consent decree or order or is subject to any judgment, decree or<br \/>\njudicial order relating to compliance with Environmental Laws, Environmental<br \/>\nPermits or the investigation, sampling, monitoring, treatment, remediation,<br \/>\nremoval or cleanup of Hazardous Materials and, to<\/p>\n<p>                                       18<\/p>\n<p>the Knowledge of the Company, no investigation, litigation or other proceeding<br \/>\nis pending or threatened in writing with respect thereto or (ii) is an<br \/>\nindemnitor in connection with any claim threatened or asserted in writing by any<br \/>\nthird-party indemnitee for any liability under any Environmental Law or relating<br \/>\nto any Hazardous Materials.<\/p>\n<p>     (d) None of the real property owned or leased by the Company or any Company<br \/>\nSubsidiary is listed or, to the Knowledge of the Company, proposed for listing<br \/>\non the &#8220;National Priorities List&#8221; under CERCLA, as updated through the date<br \/>\nhereof, or any similar state or foreign list of sites requiring investigation or<br \/>\ncleanup.<\/p>\n<p>     Section 3.15  Intellectual Property. Except as would not, individually or<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nin the aggregate, reasonably be expected to have a Company Material Adverse<br \/>\nEffect, (i) the Company (or one of its Subsidiaries) owns or has the right to<br \/>\nuse, whether through ownership, licensing or otherwise, all Company Intellectual<br \/>\nProperty, (ii) no written claim of invalidity or conflicting ownership rights<br \/>\nwith respect to any Company Intellectual Property has been received by the<br \/>\nCompany or any Company Subsidiary from a third party, (iii) no Company<br \/>\nIntellectual Property owned by the Company or any Company Subsidiary is the<br \/>\nsubject of any pending or, to the Company&#8217;s Knowledge, threatened action, suit,<br \/>\nclaim, investigation, arbitration, validity or enforceability challenge or other<br \/>\nproceeding, (iv) to the Company&#8217;s Knowledge, no Company Intellectual Property<br \/>\nthat is not owned by the Company or any Company Subsidiary is the subject of any<br \/>\npending or threatened action, suit, claim, investigation, arbitration, validity<br \/>\nor enforceability challenge or other proceeding, (v) no person has given written<br \/>\nnotice to the Company or any Company Subsidiary that the use of any Company<br \/>\nIntellectual Property by the Company, any Company Subsidiary or any licensee is<br \/>\ninfringing or has infringed any patent, trademark, service mark, trade name, or<br \/>\ncopyright or design right or other intellectual property right of any third<br \/>\nparty, or that the Company, any Company Subsidiary or any licensee has<br \/>\nmisappropriated or improperly used or disclosed any trade secret, confidential<br \/>\ninformation or know-how, (vi) to the Company&#8217;s knowledge after due inquiry, the<br \/>\nmaking, having made, using, selling, offering for sale, importing, exporting,<br \/>\nmanufacturing, marketing, licensing, reproduction, distribution or publishing by<br \/>\nthe Company of any process, machine, manufacture or product does not, because of<br \/>\nand to the extent that such process, manufacture or product incorporates Company<br \/>\nIntellectual Property, infringe any valid claim of any patent, trademark,<br \/>\nservice mark, trade name, copyright, design right, or other intellectual<br \/>\nproperty right of any third party in the jurisdictions in which such making,<br \/>\nusing, selling, offering for sale, importing, exporting, manufacturing,<br \/>\nmarketing, licensing, reproduction, distribution, or publishing occurs, and does<br \/>\nnot involve the misappropriation or improper use or disclosure of any trade<br \/>\nsecrets, confidential information or know-how of any third party, and (vii)<br \/>\nthere exists no prior act or current conduct or use by the Company, any Company<br \/>\nSubsidiary or, to the Knowledge of the Company, any third party that would void<br \/>\nor invalidate any Company Intellectual Property. As of the date hereof, AHP has<br \/>\nnot made any Product Calls (as such term is defined in the Product Rights<br \/>\nAgreement by and among the Wyeth-Ayerst Research division of AHP, the Lederle<br \/>\nPharmaceutical division of American Cyanamid Company and the Company dated as of<br \/>\nJuly 1, 1998, as amended (the &#8220;Product Rights Agreement&#8221;)) under the Product<br \/>\n                               &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nRights Agreement.<\/p>\n<p>                                       19<\/p>\n<p>     Section 3.16 Taxes.<br \/>\n                  &#8212;&#8211;<\/p>\n<p>     (a) Each of the Company and each Company Subsidiary has duly and timely<br \/>\nfiled with the appropriate Tax authorities or other Governmental Entities all<br \/>\nmaterial Tax Returns that it was required to file. All such Tax Returns are<br \/>\ncomplete and accurate in all material respects. All Taxes shown as due on such<br \/>\nTax Returns have been paid, and the Company and the Company Subsidiaries have<br \/>\nprovided adequate reserves in accordance with GAAP in the most recent financial<br \/>\nstatements contained in the Company SEC Filings for any material Taxes that have<br \/>\nnot been paid, whether or not shown as being due on any Tax Returns. None of the<br \/>\nCompany nor any Company Subsidiary currently is the beneficiary of any extension<br \/>\nof time within which to file any material Tax Return.<\/p>\n<p>     (b) No claim for unpaid material Taxes has been asserted in writing by a<br \/>\nTax authority or other Governmental Entity or has become a lien against the<br \/>\nproperty of the Company or any Company Subsidiary (other than with respect to<br \/>\nPermitted Liens for Taxes). No audit or other proceeding with respect to any<br \/>\nmaterial Taxes due from or with respect to the Company or any Company Subsidiary<br \/>\nor any material Tax Return filed by the Company or any Company Subsidiary is<br \/>\nbeing conducted by any Tax authority or Governmental Entity, and the Company and<br \/>\nthe Company Subsidiaries have not received notification in writing that any such<br \/>\naudit or other proceeding with respect to material Taxes or any material Tax<br \/>\nReturn is pending. No extension of the statute of limitations on the assessment<br \/>\nof any material Taxes has been granted by the Company or any Company Subsidiary.<\/p>\n<p>     (c) All material Taxes required to be withheld, collected or deposited by<br \/>\nor with respect to the Company and each Company Subsidiary have been timely<br \/>\nwithheld, collected or deposited as the case may be, and to the extent required,<br \/>\nhave been paid to the relevant Tax authority or other Governmental Entity.<\/p>\n<p>     (d) Neither the Company nor any Company Subsidiary is responsible for the<br \/>\nTaxes of any person other than members of the affiliated group of which the<br \/>\nCompany is the common parent under Treasury Regulation Section 1.1502-6 (or any<br \/>\nsimilar provision of state, local, or foreign Law), as a transferee, by<br \/>\nContract, or otherwise. Neither the Company nor any Company Subsidiary is a<br \/>\nparty to, is bound by or has any obligation under any Tax sharing or Tax<br \/>\nindemnity agreement or similar Contract or arrangement.<\/p>\n<p>     (e) Neither the Company nor any Company Subsidiary has been a party to any<br \/>\ndistribution occurring during the two years preceding the date of this Agreement<br \/>\nin which the parties to such distribution treated the distribution as one to<br \/>\nwhich Section 355 of the Code is applicable.<\/p>\n<p>     Section 3.17 Insurance. Copies of all material insurance policies<br \/>\n                  &#8212;&#8212;&#8212;<br \/>\nmaintained by the Company, including fire and casualty, general liability,<br \/>\nproduct liability, business interruption and professional liability policies,<br \/>\nhave been made available to Parent.<\/p>\n<p>     Section 3.18 Properties. Each of the Company and the Company Subsidiaries<br \/>\n                  &#8212;&#8212;&#8212;-<br \/>\nhas good and valid title to or a valid leasehold interest in all its properties<br \/>\nand assets reflected on the most recent balance sheet contained in the Company&#8217;s<br \/>\nquarterly report on Form 10-Q that is<\/p>\n<p>                                       20<\/p>\n<p>part of the Company SEC Filings or acquired after the date thereof, except for<br \/>\n(i) properties and assets sold or otherwise disposed of in the ordinary course<br \/>\nof business since the date of such balance sheet and (ii) properties and assets<br \/>\nthe loss of which would not, individually or in the aggregate, reasonably be<br \/>\nexpected to have a Company Material Adverse Effect.<\/p>\n<p>     Section 3.19 Regulatory Compliance.<br \/>\n                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>     (a) All biological and drug products being manufactured, distributed, or<br \/>\ndeveloped by the Company and its Subsidiaries (&#8220;Company Pharmaceutical<br \/>\n                                               &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nProducts&#8221;) that are subject to the jurisdiction of the FDA are being<br \/>\n&#8212;&#8212;&#8212;<br \/>\nmanufactured, labeled, stored, tested, distributed, and marketed in compliance<br \/>\nwith all applicable requirements under the FDCA, the Public Health Service Act,<br \/>\nand their applicable implementing regulations, except for noncompliances which<br \/>\nwould not, individually or in the aggregate, reasonably be expected to have a<br \/>\nCompany Material Adverse Effect.<\/p>\n<p>     (b) All preclinical trials and clinical trials conducted by or on behalf of<br \/>\nthe Company and its Subsidiaries have been, and are being conducted in material<br \/>\ncompliance with the applicable requirements of Good Clinical Practice, Informed<br \/>\nConsent, and all applicable requirements relating to protection of human<br \/>\nsubjects contained in 21 C.F.R. Parts 50, 54, and 56, except for noncompliances<br \/>\nwhich, individually or in the aggregate, would reasonably not be expected to<br \/>\nhave a Company Material Adverse Effect.<\/p>\n<p>     (c) All manufacturing operations conducted by or for the benefit of the<br \/>\nCompany and its Subsidiaries have been and are being conducted in compliance<br \/>\nwith the FDA&#8217;s applicable current Good Manufacturing Practice regulations for<br \/>\ndrug and biological products, except for noncompliances which, individually or<br \/>\nin the aggregate, would not reasonably be expected to have a Company Material<br \/>\nAdverse Effect. In addition, the Company and its Subsidiaries are in compliance<br \/>\nwith all applicable registration and listing requirements set forth in 21 U.S.C.<br \/>\nSection 360 and 21 C.F.R. Part 207 and all similar applicable laws, except for<br \/>\nnoncompliances which, individually or in the aggregate, would not reasonably be<br \/>\nexpected to have a Company Material Adverse Effect.<\/p>\n<p>     (d) No Company Pharmaceutical Product has been recalled, suspended or<br \/>\ndiscontinued as a result of any action by the FDA or any other similar foreign<br \/>\nGovernmental Entity by the Company or any of its Subsidiaries or, to the<br \/>\nKnowledge of the Company, any licensee, distributor or marketer of any Company<br \/>\nPharmaceutical Product, in the United States or outside of the United States<br \/>\nsince January 1, 1999.<\/p>\n<p>     (e) Neither the Company nor any of its Subsidiaries have received any<br \/>\nnotice since January 1, 1999 that the FDA or any other Governmental Entity has<br \/>\ncommenced, or threatened to initiate, any action to withdraw approval, place<br \/>\nmarketing or sale restrictions, or request the recall of any Company<br \/>\nPharmaceutical Product, or commenced, or threatened to initiate, any action to<br \/>\nenjoin or place restrictions on the production, sale, marketing or reimbursement<br \/>\nof any Company Pharmaceutical Products.<\/p>\n<p>     (f) Neither the Company, nor any of its Subsidiaries, have committed any<br \/>\nact, made any statement or failed to make any statement that would reasonably be<br \/>\nexpected to<\/p>\n<p>                                       21<\/p>\n<p>provide a basis for the FDA to invoke its policy with respect to &#8220;Fraud, Untrue<br \/>\nStatements of Material Facts, Bribery, and Illegal Gratuities&#8221; set forth in 56<br \/>\nFed. Reg. 46191 (September 10, 1991) and any amendments thereto. Additionally,<br \/>\nneither the Company, the Company Subsidiaries, nor to the Knowledge of the<br \/>\nCompany, any officer, key employee or agent of the Company has been convicted of<br \/>\nany crime or engaged in any conduct that would reasonably be expected to result<br \/>\nin (i) debarment under 21 U.S.C. Section 335a or any similar state law or<br \/>\nregulation or (ii) exclusion under 42 U.S.C. Section 1320a-7 or any similar<br \/>\nstate law or regulation.<\/p>\n<p>     Section 3.20 Opinion of Financial Advisor. Merrill Lynch &amp; Co. (the<br \/>\n                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\n&#8220;Company Financial Advisor&#8221;) has delivered to the Board of Directors of the<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nCompany its opinion that, as of the date of such opinion, the Merger<br \/>\nConsideration to be received by the holders of the shares of Company Common<br \/>\nStock pursuant to the Merger is fair to such holders from a financial point of<br \/>\nview.<\/p>\n<p>     Section 3.21 Vote Required. The affirmative vote of the holders of a<br \/>\n                  &#8212;&#8212;&#8212;&#8212;-<br \/>\nmajority of the outstanding shares of Company Common Stock is the only vote of<br \/>\nthe holders of any class or series of capital stock or other Equity Interests of<br \/>\nthe Company necessary to approve this Agreement, the Merger and the transactions<br \/>\ncontemplated hereby (the &#8220;Company Shareholder Approval&#8221;).<br \/>\n                         &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\n     Section 3.22 Brokers. No broker, finder or investment banker (other than<br \/>\n                  &#8212;&#8212;-<br \/>\nthe Company Financial Advisor) is entitled to any brokerage, finder&#8217;s or other<br \/>\nfee or commission in connection with the Merger based upon arrangements made by<br \/>\nor on behalf of the Company or any Company Subsidiary. Prior to the date hereof,<br \/>\nthe Company has accurately described to Parent the Company&#8217;s arrangements with,<br \/>\nand the fees that may be paid by the Company to, the Company Financial Advisor<br \/>\nrelating to the Merger.<\/p>\n<p>                                   ARTICLE 4.<br \/>\n             REPRESENTATIONS AND WARRANTIES OF PARENT AND MERGER SUB<\/p>\n<p>     Except as set forth in the corresponding section of the Disclosure Letter<br \/>\ndelivered by Parent and Merger Sub to the Company prior to the execution of this<br \/>\nAgreement (the &#8220;Parent Disclosure Letter&#8221;) (and subject to Section 9.13 hereof),<br \/>\n                &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nParent and Merger Sub hereby jointly and severally represent and warrant to the<br \/>\nCompany as follows:<\/p>\n<p>     Section 4.1 Organization and Qualification; Subsidiaries. Parent is a<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\ncorporation duly organized, validly existing and in good standing under the Laws<br \/>\nof Delaware. Merger Sub is a corporation duly organized and validly existing<br \/>\nunder the laws of the State of Washington and has paid all excise taxes required<br \/>\nby the Washington Department of Revenue. Each Significant Subsidiary of Parent<br \/>\n(together with Merger Sub, the &#8220;Parent Subsidiaries&#8221;) has been duly organized<br \/>\n                               &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nand is validly existing and in good standing under the Laws of the jurisdiction<br \/>\nof its incorporation, except where the failure to be so organized, existing or<br \/>\nin good standing would not, individually or in the aggregate, reasonably be<br \/>\nexpected to have a Parent Material Adverse Effect. Each of Parent and the Parent<br \/>\nSubsidiaries has the requisite power and authority and all necessary<br \/>\ngovernmental approvals to own, lease and operate its properties and to carry on<br \/>\nits business as it is now being conducted, except where the failure have such<br \/>\npower,<\/p>\n<p>                                       22<\/p>\n<p>authority and governmental approvals would not, individually or in the<br \/>\naggregate, reasonably be expected to have a Parent Material Adverse Effect. Each<br \/>\nof Parent and the Parent Subsidiaries is duly qualified or licensed to do<br \/>\nbusiness, and is in good standing (but only with respect to jurisdictions which<br \/>\nrecognize such concepts) in each jurisdiction where the character of the<br \/>\nproperties owned, leased or operated by it or the nature of its business makes<br \/>\nsuch qualification or licensing or good standing necessary, except for such<br \/>\nfailures to be so qualified or licensed and in good standing that would not,<br \/>\nindividually or in the aggregate, reasonably be expected to have a Parent<br \/>\nMaterial Adverse Effect.<\/p>\n<p>     Section 4.2 Certificate of Incorporation and Bylaws; Corporate Books and<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nRecords. The copies of the Parent Certificate and Parent&#8217;s Amended and Restated<br \/>\n&#8212;&#8212;-<br \/>\nBylaws (the &#8220;Parent Bylaws&#8221;) that are listed as exhibits to Parent&#8217;s Form 10-K<br \/>\n            &#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nfor the year ended December 31, 2000 are complete and correct copies thereof as<br \/>\nin effect on the date hereof. The Parent is not in violation of any of the<br \/>\nprovisions of the Parent Certificate or the Parent Bylaws as of the date hereof<br \/>\nand will not, as of the Closing Date, be in violation of any of the provisions<br \/>\nof the Parent Certificate or Parent Bylaws, as such Parent Certificate and<br \/>\nParent Bylaws may be amended between the date hereof and the Closing Date. True<br \/>\nand complete copies of all minute books of Parent since January 1, 1999 have<br \/>\nbeen made available by Parent to the Company.<\/p>\n<p>     Section 4.3 Capitalization.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>     (a) As of the date hereof, the authorized capital stock of Parent consists<br \/>\nof (a) 2,750,000,000 shares of Parent Common Stock and (b) 5,000,000 shares of<br \/>\npreferred stock, par value $0.0001 per share (the &#8220;Parent Preferred Stock&#8221;). As<br \/>\n                                                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nof November 30, 2001, (a) 1,048,325,488 shares of Parent Common Stock were<br \/>\nissued and outstanding, all of which were validly issued and fully paid,<br \/>\nnonassessable and free of preemptive rights and (b) 8,659,960 shares of Parent<br \/>\nCommon Stock were held in the treasury of Parent or by Parent&#8217;s Subsidiaries. As<br \/>\nof the date hereof, 687,500 shares of Parent Preferred Stock are designated as<br \/>\nSeries A Junior Participating Preferred Stock, and no shares of Parent Preferred<br \/>\nStock are issued or outstanding. As of November 30, 2001, 95,657,177 shares of<br \/>\nParent Common Stock were reserved for issuance upon exercise of stock options,<br \/>\nrights and warrants outstanding as of such date. Except for stock options and<br \/>\nagreements or arrangements described in the Parent SEC Filings, including the<br \/>\nnotes or exhibits thereto, filed prior to the date of this Agreement and<br \/>\npursuant to the rights outstanding under the Rights Plan, as of the date hereof,<br \/>\nthere are no options, warrants or other rights, agreements, arrangements or<br \/>\ncommitments of any character to which Parent or any Parent Subsidiary is a party<br \/>\nor by which Parent or any Parent Subsidiary is bound relating to the issued or<br \/>\nunissued capital stock or other Equity Interests, or obligating Parent or any<br \/>\nParent Subsidiary to issue or sell any shares of its capital stock or other<br \/>\nEquity Interests. From November 30, 2001 to the date of this Agreement, Parent<br \/>\nhas not issued any Equity Interests with respect to Parent Common Stock, other<br \/>\nthan (x) Parent Common Stock issued upon exercise of stock options and (y)<br \/>\nEquity Interests granted or issued under existing stock-based incentive<br \/>\ncompensation plans. The shares of Parent Common Stock to be issued in connection<br \/>\nwith the Merger, when issued as contemplated herein, will be duly authorized,<br \/>\nvalidly issued, fully paid and nonassessable and will not be issued in violation<br \/>\nof any preemptive rights. Except as disclosed in the Parent SEC Filings,<br \/>\nincluding the notes and exhibits thereto, as of the date hereof, there are no<br \/>\noutstanding contractual obligations of Parent or any Parent Subsidiary (a)<br \/>\nrestricting the transfer of, or (b) requiring the repurchase, redemption or<br \/>\ndisposition of, or containing any right of first refusal<\/p>\n<p>                                       23<\/p>\n<p>with respect to, any Parent Common Stock or any capital stock of, or other<br \/>\nEquity Interests in, any Parent Subsidiary. As of the date hereof, there are no<br \/>\noutstanding contractual obligations of Parent or any Parent Subsidiary (a)<br \/>\nrequiring the registration for sale of, (b) granting any preemptive or<br \/>\nantidilutive right with respect to, or (c) affecting the voting rights (except<br \/>\nfor the Stockholders&#8217; Rights Agreement by and among Parent, AHP, MDP Holdings,<br \/>\nInc. and Lederle Parenterals, Inc., dated as of the date hereof) of, any Parent<br \/>\nCommon Stock. Except as disclosed in the Parent SEC Filings, including the notes<br \/>\nand exhibits thereto, as of the date hereof, there are no outstanding<br \/>\ncontractual obligations of Parent or any Parent Subsidiary (a) affecting the<br \/>\nvoting rights of, (b) requiring the registration for sale of, or (c) granting<br \/>\nany preemptive or antidilutive right with respect to or any capital stock of, or<br \/>\nother Equity Interests in, any Parent Subsidiary.<\/p>\n<p>     (b) Each outstanding share of capital stock of each Parent Subsidiary is<br \/>\nduly authorized, validly issued, fully paid, nonassessable and free of<br \/>\npreemptive rights and is owned, beneficially and of record, by Parent free and<br \/>\nclear of all security interests, liens, claims, pledges, options, rights of<br \/>\nfirst refusal, agreements, limitations on Parent&#8217;s or any Parent Subsidiary&#8217;s<br \/>\nvoting rights, charges and other encumbrances of any nature whatsoever.<\/p>\n<p>     (c) Except as a result of the Voting Agreement, neither Parent nor any<br \/>\nParent Subsidiary beneficially owns any Equity Interest in the Company.<\/p>\n<p>     Section 4.4 Authority Relative to This Agreement. Each of Parent and Merger<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nSub has all necessary corporate power and authority to execute and deliver this<br \/>\nAgreement, to perform its obligations hereunder and to consummate the<br \/>\ntransactions contemplated by this Agreement. Each of (a) the execution and<br \/>\ndelivery of this Agreement by each of Parent and Merger Sub and the consummation<br \/>\nby Parent and Merger Sub of such transactions and (b) the issuance of shares of<br \/>\nParent Common Stock in accordance with the Merger has been duly and validly<br \/>\nauthorized by all necessary corporate action by Parent and Merger Sub and no<br \/>\nother corporate proceedings on the part of Parent and Merger Sub and no other<br \/>\nstockholder votes are necessary to authorize this Agreement or to consummate<br \/>\nsuch transactions, other than, with respect to the Share Issuance, as provided<br \/>\nin Section 4.16. The Board of Directors of Parent, by resolutions adopted by<br \/>\nunanimous vote of those voting (and not subsequently rescinded or modified in<br \/>\nany way) at a meeting duly called and held at which a quorum was present and<br \/>\nacting throughout, has duly (i) determined that this Agreement and the Merger<br \/>\nare fair to and in the best interests of Parent and its stockholders, and has<br \/>\ndeclared the Merger to be advisable, (ii) approved and adopted this Agreement,<br \/>\nthe Merger, the Share Issuance and the other transactions contemplated hereby,<br \/>\n(iii) resolved to recommend the Share Issuance to its stockholders for approval<br \/>\nand (iv) directed that the Share Issuance be submitted to its stockholders for<br \/>\nconsideration. This Agreement has been duly authorized and validly executed and<br \/>\ndelivered by Parent and Merger Sub and constitutes the legal, valid and binding<br \/>\nobligations of each of Parent and Merger Sub, enforceable against Parent and<br \/>\nMerger Sub in accordance with its terms.<\/p>\n<p>     Section 4.5 No Conflict; Required Filings and Consents.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>     (a) The execution and delivery of this Agreement by Parent and Merger Sub<br \/>\ndo not, and the performance of this Agreement by Parent and Merger Sub will not,<br \/>\n(i) conflict with or violate any provision of the certificate or articles of<br \/>\nincorporation or bylaws of Parent or<\/p>\n<p>                                       24<\/p>\n<p>Merger Sub, (ii) assuming that all consents, approvals, authorizations and<br \/>\npermits described in Section 4.5(b) have been obtained, that Parent&#8217;s<br \/>\nstockholders have approved the Share Issuance and that all filings and<br \/>\nnotifications described in Section 4.5(b) have been made, and any waiting<br \/>\nperiods thereunder have terminated or expired, conflict with or violate any Law<br \/>\napplicable to Parent or any Parent Subsidiary or by which any property or asset<br \/>\nof Parent or any Parent Subsidiary is bound or affected or (iii) require any<br \/>\nconsent or approval under, result in any breach of, any loss of any benefit<br \/>\nunder or constitute a change of control or default (or an event which with<br \/>\nnotice or lapse of time or both would become a default) under, or give to others<br \/>\nany right of termination, vesting, amendment, acceleration or cancellation of,<br \/>\nor result in the creation of a lien or other encumbrance on any property or<br \/>\nasset of Parent or any Parent Subsidiary pursuant to, any Contract, except, with<br \/>\nrespect to clauses (ii) and (iii), for any such conflicts, violations, breaches,<br \/>\ndefaults or other occurrences which would not, individually or in the aggregate,<br \/>\nreasonably be expected to (x) have a Parent Material Adverse Effect or (y)<br \/>\nprevent or materially delay the performance of this Agreement by Parent or<br \/>\nMerger Sub.<\/p>\n<p>     (b) The execution and delivery of this Agreement by Parent and Merger Sub<br \/>\ndo not, and the performance of this Agreement by Parent and Merger Sub will not,<br \/>\nrequire any consent, approval, authorization or permit of, or filing with or<br \/>\nnotification to, any domestic or foreign Governmental Entity or any other<br \/>\nperson, except (i) under the Exchange Act, the Securities Act, any applicable<br \/>\nBlue Sky Law, the rules and regulations of Nasdaq, the HSR Act, foreign or<br \/>\nsupranational antitrust and competition Laws, and the filing and recordation of<br \/>\nthe Articles of Merger as required by the WBCA and (ii) where failure to obtain<br \/>\nsuch consents, approvals, authorizations or permits, or to make such filings or<br \/>\nnotifications to a person other than a Governmental Entity, would not,<br \/>\nindividually or in the aggregate, reasonably be expected to (x) have a Parent<br \/>\nMaterial Adverse Effect or (y) prevent or materially delay the performance under<br \/>\nthis Agreement by Parent or Merger Sub.<\/p>\n<p>     Section 4.6 Permits; Compliance With Law. Parent and each Parent Subsidiary<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nis in possession of all authorizations, licenses, permits, certificates,<br \/>\napprovals and clearances necessary to carry on their respective businesses in<br \/>\nthe manner described in the Parent SEC Filings filed prior to the date hereof<br \/>\nand as it is being conducted as of the date hereof (the &#8220;Parent Permits&#8221;), and<br \/>\n                                                        &#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nall such Parent Permits are valid and in full force and effect, except where the<br \/>\nfailure to have, or the suspension or cancellation of, or failure to be valid or<br \/>\nin full force and effect of, any of the Parent Permits would not, individually<br \/>\nor in the aggregate, reasonably be expected to have a Parent Material Adverse<br \/>\nEffect. Neither Parent nor any Parent Subsidiary is in conflict with any Law<br \/>\napplicable to Parent or any Parent Subsidiary that would, individually or in the<br \/>\naggregate, reasonably be expected to have a Parent Material Adverse Effect.<\/p>\n<p>     Section 4.7 SEC Filings; Financial Statements.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>     (a) Parent has timely filed all registration statements, prospectuses,<br \/>\nforms, reports, definitive proxy statements, schedules and documents required to<br \/>\nbe filed by it under the Securities Act or the Exchange Act, as the case may be,<br \/>\nsince January 1, 1998 (collectively, the &#8220;Parent SEC Filings&#8221;). Each Parent SEC<br \/>\n                                         &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nFiling (i) as of its date, complied in all material respects with the<br \/>\nrequirements of the Securities Act or the Exchange Act, as the case may be and<br \/>\n(ii) did not at the time it was filed contain any untrue statement of a material<br \/>\nfact or omit to state a material fact required to be stated therein or necessary<br \/>\nin order to make the statements made<\/p>\n<p>                                       25<\/p>\n<p>therein, in the light of the circumstances under which they were made, not<br \/>\nmisleading. As of the date of this Agreement, no Subsidiary of Parent is subject<br \/>\nto the periodic reporting requirements of the Exchange Act.<\/p>\n<p>     (b) Each of the consolidated financial statements (including, in each case,<br \/>\nany notes thereto) contained in the Parent SEC Filings was prepared in all<br \/>\nmaterial respects in accordance with GAAP applied (except as may be indicated in<br \/>\nthe notes thereto and, in the case of unaudited quarterly financial statements,<br \/>\nas permitted by Form 10-Q under the Exchange Act) on a consistent basis<br \/>\nthroughout the periods indicated (except as may be indicated in the notes<br \/>\nthereto), and each presented fairly the consolidated financial position, results<br \/>\nof operations and cash flows of Parent and its consolidated Subsidiaries as of<br \/>\nthe respective dates thereof and for the respective periods indicated therein<br \/>\n(subject, in the case of unaudited statements, to normal and recurring year-end<br \/>\nadjustments which did not and would not, individually or in the aggregate,<br \/>\nreasonably be expected to have a Parent Material Adverse Effect). The books and<br \/>\nrecords of Parent and its Subsidiaries have been, and are being, maintained in<br \/>\nall material respects in accordance with GAAP and any other applicable legal and<br \/>\naccounting requirements.<\/p>\n<p>     (c) Except as and to the extent set forth on the consolidated balance sheet<br \/>\nof Parent and its consolidated Subsidiaries as of December 31, 2000 included in<br \/>\nParent&#8217;s Form 10-K for the year ended December 31, 2000, including the notes<br \/>\nthereto (the &#8220;Parent Form 10-K&#8221;), neither Parent nor any of its consolidated<br \/>\n             &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nSubsidiaries has any liabilities or obligations of any nature (whether accrued,<br \/>\nabsolute, contingent or otherwise) that would be required to be reflected on a<br \/>\nbalance sheet or in notes thereto prepared in accordance with GAAP, except for<br \/>\nliabilities or obligations incurred in the ordinary course of business<br \/>\nconsistent with past practice since December 31, 2000 and liabilities incurred<br \/>\nin connection with this Agreement and the transactions contemplated hereby that<br \/>\nwould not, individually or in the aggregate, reasonably be expected to have a<br \/>\nParent Material Adverse Effect.<\/p>\n<p>     (d) As of the date hereof, no &#8220;material contract&#8221; (as such term is defined<br \/>\nin Item 601(b)(10) of Regulation S-K of the SEC) filed as an exhibit to the<br \/>\nParent Form 10-K has been amended or modified, except for such amendments or<br \/>\nmodifications which have been filed as an exhibit to a subsequently dated Parent<br \/>\nSEC Filing or are not required to be filed with the SEC.<\/p>\n<p>     Section 4.8   Absence of Certain Changes or Events. Since December 31,<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\n2000, except as disclosed in the Parent Form 10-K or in Parent SEC Filings since<br \/>\nDecember 31, 2000 through to the date of this Agreement, including the notes<br \/>\nthereto, and except as specifically contemplated by, or as disclosed in, this<br \/>\nAgreement, Parent and its Subsidiaries have conducted their business in the<br \/>\nordinary course consistent with past practice and, since such date, there has<br \/>\nnot been (a) an event or development that would, individually or in the<br \/>\naggregate, reasonably be expected to have a Parent Material Adverse Effect or<br \/>\n(b) any event or development that would, individually or in the aggregate,<br \/>\nreasonably be expected to prevent or materially delay the performance of this<br \/>\nAgreement by Parent or Merger Sub.<\/p>\n<p>     Section 4.9   Litigation. Except as disclosed in the Parent SEC Filings,<br \/>\n                   &#8212;&#8212;&#8212;-<br \/>\nincluding the notes thereto, filed prior to the date of this Agreement or would<br \/>\nnot, individually or in the aggregate, reasonably be expected to have a Parent<br \/>\nMaterial Adverse Effect, (i) there is no<\/p>\n<p>                                       26<\/p>\n<p>suit, claim, action, proceeding or investigation pending or, to the Knowledge of<br \/>\nParent, threatened in writing against Parent or any Parent Subsidiary or for<br \/>\nwhich Parent or any Parent Subsidiary is obligated to indemnify a third party,<br \/>\nand (ii) neither Parent nor any Parent Subsidiary is subject to any outstanding<br \/>\nand unsatisfied order, writ, injunction, decree or arbitration ruling, award or<br \/>\nother finding. There is no suit, claim, action, proceeding or investigation<br \/>\npending or, to the Knowledge of Parent, threatened in writing against Parent or<br \/>\nany Parent Subsidiary that, as of the date hereof, challenges the validity or<br \/>\npropriety, or seeks to prevent consummation of, the Merger or any other<br \/>\ntransaction contemplated by this Agreement.<\/p>\n<p>     Section 4.10   Environmental Matters. Except as disclosed in the Parent<br \/>\n                    &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nForm 10-K or in the Parent SEC Filings, including the notes thereto, since<br \/>\nDecember 31, 2000 through the date of this Agreement or would not, individually<br \/>\nor in the aggregate, reasonably be expected to have a Parent Material Adverse<br \/>\nEffect, Parent and the Parent Subsidiaries (i) are in compliance with all, and<br \/>\nare not subject to any liability, in each case with respect to any, applicable<br \/>\nEnvironmental Laws, (ii) hold or have applied for all Environmental Permits<br \/>\nnecessary to conduct their current operations, and (iii) are in compliance with<br \/>\ntheir respective Environmental Permits.<\/p>\n<p>     Section 4.11   Intellectual Property. Except as disclosed in the Parent<br \/>\n                    &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nForm 10-K or in the Parent SEC Filings, including the notes thereto, since<br \/>\nDecember 31, 2000 through the date of this Agreement or would not, individually<br \/>\nor in the aggregate, reasonably be expected to have a Parent Material Adverse<br \/>\nEffect: (i) Parent and its Subsidiaries own or have the right to use, whether<br \/>\nthrough ownership, licensing or otherwise, all Parent Intellectual Property,<br \/>\n(ii) no Parent Intellectual Property is the subject of any pending or, to<br \/>\nParent&#8217;s Knowledge, threatened action, suit, claim, investigation, arbitration<br \/>\nor other proceeding, (iii) there exists no prior act or current conduct or use<br \/>\nby Parent or any Parent Subsidiary or, to the Knowledge of Parent, any third<br \/>\nparty that would void or invalidate any Parent Intellectual Property, and (iv)<br \/>\nto the Knowledge of Parent, the making, using, selling, manufacturing,<br \/>\nmarketing, licensing, reproduction, distribution or publishing by Parent of any<br \/>\nprocess, manufacture or product does not, because of and to the extent that such<br \/>\nprocess, manufacture or product incorporates Parent Intellectual Property,<br \/>\ninfringe any valid claim of patent, trademark, service mark, trade name,<br \/>\ncopyright or other intellectual property right of any third party in the<br \/>\njurisdictions in which such making, using, selling, manufacturing, marketing,<br \/>\nlicensing, reproduction, distribution, or publishing occurs, and does not<br \/>\ninvolve the misappropriation or improper use or disclosure of any trade secrets,<br \/>\nconfidential information or know-how of any third party.<\/p>\n<p>     Section 4.12 Regulatory Compliance.<br \/>\n                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>     (a) All biological and drug products being manufactured, distributed or<br \/>\ndeveloped by Parent and its Subsidiaries (&#8220;Parent Pharmaceutical Products&#8221;) that<br \/>\n                                          &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nare subject to the jurisdiction of the FDA are being manufactured, labeled,<br \/>\nstored, tested, distributed and marketed in compliance with all applicable<br \/>\nrequirements under the FDCA and the Public Health Service Act, except for<br \/>\nnoncompliances which, individually or in the aggregate, would reasonably not be<br \/>\nexpected to have a Parent Material Adverse Effect.<\/p>\n<p>     (b) Neither Parent nor any of its Subsidiaries have received any notice<br \/>\nsince January 1, 1999 that the FDA or any other Governmental Entity has<br \/>\ncommenced, or threatened<\/p>\n<p>                                       27<\/p>\n<p>to initiate, any action to withdraw approval or request the recall of any Parent<br \/>\nPharmaceutical Product, or commenced, or threatened to initiate, any action to<br \/>\nenjoin or place restrictions on the production of any Parent Pharmaceutical<br \/>\nProducts.<\/p>\n<p>     Section 4.13   Tax Treatment. None of Parent, nor any of its Subsidiaries<br \/>\n                    &#8212;&#8212;&#8212;&#8212;-<br \/>\nor Affiliates has taken or agreed to take any action that would prevent the<br \/>\nMerger from qualifying as a reorganization within the meaning of Section 368(a)<br \/>\nof the Code. Parent is not aware of any agreement, plan or other circumstance<br \/>\nthat would prevent the Merger from qualifying as a reorganization within the<br \/>\nmeaning of Section 368(a) of the Code.<\/p>\n<p>     Section 4.14   Ownership of Merger Sub; No Prior Activities.<br \/>\n                    &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n<p>     (a) Merger Sub was formed solely for the purpose of engaging in the<br \/>\ntransactions contemplated by this Agreement. All of the outstanding capital<br \/>\nstock of Merger Sub is owned directly by Parent.<\/p>\n<p>     (b) Except for obligations or liabilities incurred in connection with its<br \/>\nincorporation or organization and the transactions contemplated by this<br \/>\nAgreement, Merger Sub has not and will not have incurred, directly or<br \/>\nindirectly, through any Subsidiary or Affiliate, any obligations or liabilities<br \/>\nor engaged in any business activities of any type or kind whatsoever or entered<br \/>\ninto any agreements or arrangements with any person. Merger Sub has no<br \/>\nSubsidiaries.<\/p>\n<p>     Section 4.15 Opinion of Financial Advisor. Goldman, Sachs &amp; Co. (the<br \/>\n                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\n&#8220;Parent Financial Advisor&#8221;) has delivered to the Board of Directors of Parent<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nits opinion that, as of the date of such opinion, the Merger Consideration is<br \/>\nfair from a financial point of view to Parent.<\/p>\n<p>     Section 4.16   Vote Required. The affirmative vote of the holders of a<br \/>\n                    &#8212;&#8212;&#8212;&#8212;-<br \/>\nmajority of the shares of Parent Common Stock represented at a meeting of the<br \/>\nstockholders of Parent called for such purpose and entitled to vote thereon<br \/>\n(provided that at least a majority of such shares are represented in person or<br \/>\nby proxy at such meeting) is the only vote of the holders of any class or series<br \/>\nof capital stock or other Equity Interests of Parent necessary to approve the<br \/>\nShare Issuance (the &#8220;Parent Stockholder Approval&#8221;).<br \/>\n                     &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>     Section 4.17 Brokers. No broker, finder or investment banker (other than<br \/>\n                  &#8212;&#8212;-<br \/>\nthe Parent Financial Advisor, Bear, Stearns &amp; Co. Inc. and Salomon Smith Barney<br \/>\nInc.) is entitled to any brokerage, finder&#8217;s or other fee or commission in<br \/>\nconnection with the Merger based upon arrangements made by or on behalf of<br \/>\nParent or any of its Subsidiaries.<\/p>\n<p>     Section 4.18   Sufficient Funds. Parent will have at or prior to the<br \/>\n                    &#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nClosing and at the Effective Time sufficient immediately available funds and<br \/>\nsufficient authorized but unissued shares or treasury shares of Parent Common<br \/>\nStock to pay the Merger Consideration upon consummation of the Merger.<\/p>\n<p>                                   ARTICLE 5.<br \/>\n                                   COVENANTS<\/p>\n<p>     Section 5.1   Conduct of Business by the Company Pending the Closing. The<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nCompany agrees that, between the date of this Agreement and the Effective Time,<br \/>\nexcept as set<\/p>\n<p>                                       28<\/p>\n<p>forth in Section 5.1 of the Company Disclosure Letter or as specifically<br \/>\npermitted by any other provision of this Agreement, or unless Parent shall<br \/>\notherwise agree in writing, the Company shall, and shall cause each Company<br \/>\nSubsidiary to, (x) maintain its existence in good standing under applicable Law,<br \/>\n(y) subject to the restrictions set forth in this Section 5.1 and Section 6.5,<br \/>\nconduct its operations only in the ordinary and usual course of business<br \/>\nconsistent with past practice and (z) use its reasonable best efforts to keep<br \/>\navailable the services of the current officers, key employees and consultants of<br \/>\nthe Company and each Company Subsidiary and, subject to Section 6.5, to preserve<br \/>\nthe current relationships of the Company and the Company Subsidiaries with their<br \/>\ncustomers, suppliers and other persons with which the Company or any Company<br \/>\nSubsidiary has significant business relations as is reasonably necessary in<br \/>\norder to preserve substantially intact its business organization. In addition,<br \/>\nwithout limiting the foregoing, except as set forth in Section 5.1 of the<br \/>\nCompany Disclosure Letter or as specifically permitted by any other provision of<br \/>\nthis Agreement, the Company shall not and shall not permit any of its<br \/>\nSubsidiaries to (unless required by applicable Law or the regulations or<br \/>\nrequirements of any stock exchange or regulatory organization applicable to the<br \/>\nCompany and its Subsidiaries), between the date of this Agreement and the<br \/>\nEffective Time, directly or indirectly, do, or agree to do, any of the following<br \/>\nwithout the prior written consent of Parent:<\/p>\n<p>     (a) amend or otherwise change its articles or certificate of incorporation<br \/>\nor bylaws or equivalent organizational documents;<\/p>\n<p>     (b) issue, sell, pledge, dispose of, grant, transfer, encumber, or<br \/>\nauthorize the issuance, sale, pledge, disposition, grant, transfer or<br \/>\nencumbrance of any shares of capital stock of, or other Equity Interests in, the<br \/>\nCompany or any Company Subsidiary of any class, or securities convertible or<br \/>\nexchangeable or exercisable for any shares of such capital stock or other Equity<br \/>\nInterests, or any options, warrants or other rights of any kind to acquire any<br \/>\nshares of such capital stock or other Equity Interests or such convertible or<br \/>\nexchangeable securities, or any other ownership interest, of the Company or any<br \/>\nCompany Subsidiary, except that (i) the Company may issue shares of Company<br \/>\nCommon Stock pursuant to the ESPP or upon exercise of Company Options<br \/>\noutstanding on the date hereof or hereafter granted in accordance with the<br \/>\nprovisions of subclause (ii), (iii) or (iv) of this clause (b), (ii) the Company<br \/>\nmay grant Company Options up to an aggregate of 1,100,000 shares of Company<br \/>\nCommon Stock to newly-hired employees and may grant Company Options up to an<br \/>\naggregate of 4,400,000 shares of Company Common Stock to existing employees and<br \/>\nnon-employee directors, in each case, in accordance with the terms of the<br \/>\nCompany Stock Option Plans consistent with past practice and with an exercise<br \/>\nprice per share of Company Common Stock no less than the fair market value of a<br \/>\nshare of Company Common Stock as of the date of grant, provided that in no event<br \/>\nshall the vesting or exercisability of any such Company Options accelerate<br \/>\nsolely as a result of the consummation of the transactions contemplated by this<br \/>\nAgreement, (iii) the Company may grant Company Options that are Replacement<br \/>\nOptions pursuant to Section 2.4(b), (iv) the Company may grant Company Options<br \/>\npursuant to existing contractual relationships and as set forth in the Company<br \/>\nDisclosure Letter, (v) the Company may grant Equity Interests in accordance with<br \/>\nSections 2.01 and 2.02 of the Governance Agreement, and (vi) the Company<br \/>\nSubsidiaries may issue shares of capital stock or other Equity Interests to the<br \/>\nCompany or any wholly-owned Company Subsidiary;<\/p>\n<p>     (c) (i) sell, pledge, dispose of, transfer, lease, license, or encumber, or<br \/>\nauthorize the sale, pledge, disposition, transfer, lease, license, or<br \/>\nencumbrance of, any material<\/p>\n<p>                                       29<\/p>\n<p>property or assets (other than Company Intellectual Property) of the Company or<br \/>\nany Company Subsidiary, except (A) sales, pledges, dispositions, transfers,<br \/>\nleases, licenses or encumbrances pursuant to existing Contracts, (B) sales,<br \/>\npledges, dispositions, transfers, leases, licenses or encumbrances of property<br \/>\nor assets by the Company or a Company Subsidiary in the ordinary course of<br \/>\nbusiness but not to exceed an aggregate value for all such sales, pledges,<br \/>\ndispositions, transfers, leases, licenses and encumbrances of $100,000,000, (C)<br \/>\nsales or dispositions of inventory and other tangible current assets, or (D) as<br \/>\nmay be required pursuant to Section 6.5(b); (ii) sell, pledge, dispose of,<br \/>\ntransfer, lease, license, abandon, fail to maintain or encumber, or authorize<br \/>\nthe sale, pledge, disposition, transfer, lease, license, abandonment, failure to<br \/>\nmaintain or encumbrance of, any Company Intellectual Property (other than<br \/>\nCompany Intellectual Property that protects or enhances the value of Enbrel),<br \/>\nexcept (A) sales, pledges, dispositions, transfers, leases, licenses,<br \/>\nabandonments, failures to maintain or encumbrances in the ordinary course of<br \/>\nbusiness which will not materially impair the conduct of the Company&#8217;s business<br \/>\nand (B) as may be required pursuant to Section 6.5(b); (iii) sell, pledge,<br \/>\ndispose of, transfer, lease, license, abandon, fail to maintain or encumber, or<br \/>\nauthorize the sale, pledge, disposition, transfer, lease, license, abandonment,<br \/>\nfailure to maintain or encumbrance of, any Company Intellectual Property which<br \/>\nprotects Enbrel, except (A) agreements entered into for clinical studies<br \/>\ninvolving Enbrel in the ordinary course of business and (B) material transfer<br \/>\nagreements relating to Enbrel entered into in the ordinary course of business;<br \/>\nor (iv) enter into any material commitment or transaction outside the ordinary<br \/>\ncourse of business consistent with past practice other than transactions between<br \/>\na wholly-owned Company Subsidiary and the Company or another wholly-owned<br \/>\nCompany Subsidiary;<\/p>\n<p>     (d) declare, set aside, make or pay any dividend or other distribution<br \/>\n(whether payable in cash, stock, property or a combination thereof) with respect<br \/>\nto any of the capital stock of the Company (other than dividends or<br \/>\ndistributions paid by wholly-owned Company Subsidiaries to the Company or to<br \/>\nother wholly-owned Company Subsidiaries) or enter into any agreement with<br \/>\nrespect to the voting of the capital stock of the Company;<\/p>\n<p>     (e) (i) reclassify, combine, split or subdivide any of its capital stock or<br \/>\nissue or authorize the issuance of any other securities in respect of, in lieu<br \/>\nof, or in substitution for, shares of its capital stock, or (ii) redeem,<br \/>\npurchase or otherwise acquire, directly or indirectly, any of its capital stock,<br \/>\nother Equity Interests or other securities;<\/p>\n<p>     (f) (i) incur any indebtedness for borrowed money or issue any debt<br \/>\nsecurities or assume, guarantee or endorse, or otherwise as an accommodation<br \/>\nbecome responsible for, the obligations of any person (other than a wholly-owned<br \/>\nCompany Subsidiary) for borrowed money, except for indebtedness for borrowed<br \/>\nmoney under the Company&#8217;s existing credit facilities or replacement credit<br \/>\nfacilities in an aggregate amount not materially larger than the Company&#8217;s<br \/>\nexisting credit facilities, (ii) terminate, cancel, or agree to any material and<br \/>\nadverse change in, any Company Material Contract other than in the ordinary<br \/>\ncourse of business consistent with past practice, (iii) make or authorize any<br \/>\ncapital expenditure materially in excess of the Company&#8217;s budget as disclosed to<br \/>\nParent prior to the date hereof or (iv) make or authorize any material loan to<br \/>\nany person (other than a Company Subsidiary) outside the ordinary course of<br \/>\nbusiness;<\/p>\n<p>                                       30<\/p>\n<p>     (g) except as may be required by contractual commitments or corporate<br \/>\npolicies with respect to severance or termination pay in existence on the date<br \/>\nof this Agreement as disclosed in Section 3.9 or 6.10(c) of the Company<br \/>\nDisclosure Letter, (i) increase the compensation or benefits payable or to<br \/>\nbecome payable to its directors, officers or employees (except for increases in<br \/>\naccordance with past practices and methodologies in salaries or wages of<br \/>\nofficers and\/or employees of the Company or any Company Subsidiary), (ii) grant<br \/>\nany rights to severance or termination pay to, or enter into any employment or<br \/>\nseverance agreement with, any director, officer or other employee of the Company<br \/>\nor any Company Subsidiary (other than with respect to newly appointed directors<br \/>\nand newly hired employees in accordance with past practices of the Company or<br \/>\nany Company Subsidiary, provided that any such agreements shall not provide for<br \/>\nthe payment of any severance or termination pay solely as a result of the<br \/>\nexecution of this Agreement or the consummation of the transactions contemplated<br \/>\nhereby), (iii) establish, adopt, enter into or amend any collective bargaining,<br \/>\nbonus, profit sharing, thrift, compensation, stock option, restricted stock,<br \/>\npension, retirement, deferred compensation, employment, termination, severance<br \/>\nor other plan, agreement, trust, fund, policy or arrangement for the benefit of<br \/>\nany director, officer, consultant or employee, except to the extent required by<br \/>\napplicable Law or (iv) take any affirmative action to amend or waive any<br \/>\nperformance or vesting criteria or accelerate vesting, exercisability or funding<br \/>\nunder any Company Benefit Plan or Company Option;<\/p>\n<p>     (h) make any material change in accounting policies or procedures, other<br \/>\nthan in the ordinary course of business consistent with past practice or except<br \/>\nas required by GAAP or by a Governmental Entity;<\/p>\n<p>     (i) except in the ordinary course of business consistent with past<br \/>\npractice, make any material Tax election or settle or compromise any material<br \/>\nliability for Taxes, change any annual Tax accounting period, change any method<br \/>\nof Tax accounting, file any amended material Tax Return, enter into any closing<br \/>\nagreement relating to any material Tax, surrender any right to claim a material<br \/>\nTax refund, or consent to any extension or waiver of the statute of limitations<br \/>\nperiod applicable to any material Tax claim or assessment;<\/p>\n<p>     (j) subject to Section 6.4(h), modify, amend or terminate, or waive,<br \/>\nrelease or assign any material rights or claims with respect to any<br \/>\nconfidentiality or standstill agreement to which the Company is a party and<br \/>\nwhich relates to a business combination involving the Company;<\/p>\n<p>     (k) write up, write down or write off the book value of any assets,<br \/>\nindividually or in the aggregate, for the Company and the Company Subsidiaries<br \/>\ntaken as a whole, other than in the ordinary course of business or otherwise not<br \/>\nin excess of $50 million;<\/p>\n<p>     (l) subject to Section 6.4(h), take any action to render inapplicable, or<br \/>\nto exempt any third party from, (i) the provisions of Chapter 23B.19 of the WBCA<br \/>\nor (ii) any other state takeover Law or state Law that purports to limit or<br \/>\nrestrict business combinations or the ability to acquire or vote shares;<\/p>\n<p>     (m) acquire, or agree to acquire, from any Person any assets (not including<br \/>\nIntellectual Property), operations, business or securities or engage in, or<br \/>\nagree to engage in, any<\/p>\n<p>                                       31<\/p>\n<p>merger, consolidation or other business combination with any Person, except (i)<br \/>\nin connection with capital expenditures permitted hereunder and except for<br \/>\nacquisitions of inventory and other assets (not including Intellectual Property)<br \/>\nin the ordinary course of business or (ii) for acquisitions of businesses or<br \/>\nassets (not including Intellectual Property) or business combinations having or<br \/>\ninvolving aggregate consideration not in excess of $50,000,000, which, in the<br \/>\ncase of clauses (i) and (ii), individually or in the aggregate, would not be<br \/>\nreasonably expected to result in any of the conditions to the Merger set forth<br \/>\nin Article 7 not being satisfied;<\/p>\n<p>     (n) take any action that is intended or would reasonably be expected to<br \/>\nresult in any of the conditions to the Merger set forth in Article 7 not being<br \/>\nsatisfied;<\/p>\n<p>     (o) adopt a shareholder rights agreement, or &#8220;poison pill&#8221;;<\/p>\n<p>     (p) acquire, or agree to acquire, from any Person, any Intellectual<br \/>\nProperty, except in the ordinary course of business consistent with past<br \/>\npractice (including in size and nature); or<\/p>\n<p>     (q) authorize or enter into any agreement or otherwise make any commitment<br \/>\nto do any of the foregoing.<\/p>\n<p>     Section 5.2  Conduct of Business by Parent Pending the Closing. Parent<br \/>\n                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nagrees that, between the date of this Agreement and the Effective Time, except<br \/>\nas specifically permitted by any other provision of this Agreement or unless the<br \/>\nCompany shall otherwise agree in writing, Parent shall maintain its existence in<br \/>\ngood standing under applicable Law and Parent and its Subsidiaries shall<br \/>\ncontinue to conduct their businesses such that the primary business of Parent<br \/>\nand its Subsidiaries, taken as a whole, shall involve biotechnology or<br \/>\npharmaceuticals. Without limiting the foregoing, and as an extension thereof,<br \/>\nexcept as specifically permitted by any other provision of this Agreement,<br \/>\nParent shall not and shall not permit any of its Subsidiaries to (unless<br \/>\nrequired by applicable Laws or the regulations or requirements of any stock<br \/>\nexchange or regulatory organization applicable to Parent and its Subsidiaries),<br \/>\nbetween the date of this Agreement and the Effective Time, directly or<br \/>\nindirectly, do, or agree to do, any of the following, without the prior written<br \/>\nconsent of the Company:<\/p>\n<p>     (a) amend or otherwise change the Parent Certificate in a manner that<br \/>\nadversely affects the rights of holders of Parent Common Stock (including<br \/>\nholders of the Parent Common Stock issuable in the Merger), except to increase<br \/>\nthe authorized number of shares of Parent capital stock (including Parent Common<br \/>\nStock);<\/p>\n<p>     (b) issue any shares of Parent Common Stock if, following such issuance,<br \/>\nthere would be an insufficient number of shares of Parent Common Stock to pay<br \/>\nthe Merger Consideration and to be reserved for issuance in connection with the<br \/>\ntransactions contemplated hereby;<\/p>\n<p>     (c) declare, set aside, make or pay any dividend or other distribution,<br \/>\npayable in cash, stock property or otherwise, with respect to any of Parent&#8217;s<br \/>\ncapital stock;<\/p>\n<p>                                       32<\/p>\n<p>     (d) take any action (including any acquisition or entering into any<br \/>\nbusiness combination) that is intended or could reasonably be expected to result<br \/>\nin any of the conditions to the Merger set forth in Article 7 not being<br \/>\nsatisfied; or<\/p>\n<p>     (e) authorize or enter into any agreement or otherwise make any commitment<br \/>\nto do any of the foregoing.<\/p>\n<p>     Section 5.3  Cooperation.<br \/>\n                  &#8212;&#8212;&#8212;&#8211;<\/p>\n<p>     (a) In addition to their other obligations set forth in this Agreement, the<br \/>\nCompany and Parent shall coordinate and cooperate in connection with (a) the<br \/>\npreparation of the Registration Statement and the Proxy Statement, (b)<br \/>\ndetermining whether any action by or in respect of, or filing with, any<br \/>\nGovernmental Entity is required, or any actions, consents, approvals or waivers<br \/>\nare required to be obtained from parties to any Company Material Contracts, in<br \/>\nconnection with the consummation of the Merger, and (c) seeking any such<br \/>\nactions, consents, approvals or waivers or making any such filings, furnishing<br \/>\ninformation required in connection therewith or with the Registration Statement<br \/>\nand the Proxy Statement.<\/p>\n<p>     (b) As soon as reasonably practicable after the date hereof, Parent and<br \/>\nCompany shall establish an Integration Committee with a consultative function,<br \/>\nwhich shall be comprised of two senior executives of Parent, designated by the<br \/>\nChairman, President and Chief Executive Officer of the Parent, and two senior<br \/>\nexecutives of the Company, designated by the Chairman, President and Chief<br \/>\nExecutive Officer of the Company. Subject to applicable Law, the Integration<br \/>\nCommittee will be concerned with matters relating to the integration of Parent&#8217;s<br \/>\nand Company&#8217;s respective businesses and personnel following the Effective Time<br \/>\nand will periodically meet to discuss and review such matters.<\/p>\n<p>     Section 5.4  Tax-Free Reorganization Treatment.<br \/>\n                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>     (a) Neither Company nor Parent shall, nor shall they permit any of their<br \/>\nrespective Subsidiaries to, take or cause to be taken any action that would<br \/>\ndisqualify the Merger as a reorganization within the meaning of Section 368(a)<br \/>\nof the Code. Parent and the Company shall use their reasonable best efforts, and<br \/>\nshall cause their respective Subsidiaries to use their reasonable best efforts,<br \/>\nto take or cause to be taken any action that would cause the Merger to qualify<br \/>\nas a reorganization within the meaning of Section 368(a) of the Code.<\/p>\n<p>     (b) Each of the Company and Parent shall report the Merger as a<br \/>\nreorganization within the meaning of Section 368 of the Code, unless otherwise<br \/>\nrequired pursuant to a &#8220;determination&#8221; within the meaning of Section 1313(a) of<br \/>\nthe Code.<\/p>\n<p>     Section 5.5  Control of Other Party&#8217;s Business. Nothing contained in this<br \/>\n                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nAgreement shall give Parent or Merger Sub, directly or indirectly, the right to<br \/>\ncontrol or direct the operations of the Company prior to the consummation of the<br \/>\nMerger. Prior to the consummation of the Merger, the Company shall exercise,<br \/>\nconsistent with the terms and conditions of this Agreement, complete control and<br \/>\nsupervision over its operations.<\/p>\n<p>                                       33<\/p>\n<p>                                   ARTICLE 6.<br \/>\n                              ADDITIONAL AGREEMENTS<\/p>\n<p>     Section 6.1 Registration Statement; Proxy Statement.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>     (a) As promptly as practicable after the execution of this Agreement,<br \/>\nParent and the Company shall prepare and file with the SEC a joint proxy<br \/>\nstatement relating to the Company Shareholders&#8217; Meeting and Parent Stockholders&#8217;<br \/>\nMeeting (together with any amendments thereof or supplements thereto, the &#8220;Proxy<br \/>\n                                                                          &#8212;&#8212;<br \/>\nStatement&#8221;) and Parent shall prepare and file with the SEC a registration<br \/>\n&#8212;&#8212;&#8212;-<br \/>\nstatement on Form S-4 (together with all amendments thereto, the &#8220;Registration<br \/>\n                                                                 &#8212;&#8212;&#8212;&#8212;-<br \/>\nStatement&#8221;; the prospectus contained in the Registration Statement together with<br \/>\n&#8212;&#8212;&#8212;-<br \/>\nthe Proxy Statement, the &#8220;Joint Proxy\/Prospectus&#8221;), in which the Proxy Statement<br \/>\n                         &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nshall be included, in connection with the registration under the Securities Act<br \/>\nof the shares of Parent Common Stock to be issued to the shareholders of the<br \/>\nCompany as Merger Consideration. Each of Parent and the Company shall use<br \/>\nreasonable best efforts to cause the Registration Statement to become effective<br \/>\nas promptly as practicable, and, prior to the effective date of the Registration<br \/>\nStatement, Parent shall take all or any action reasonably required under any<br \/>\napplicable federal or state securities Laws in connection with the issuance of<br \/>\nshares of Parent Common Stock in the Merger. Each of Parent and the Company<br \/>\nshall furnish all information concerning it and the holders of its capital stock<br \/>\nas the other may reasonably request in connection with such actions and the<br \/>\npreparation of the Registration Statement and Proxy Statement. As promptly as<br \/>\nreasonably practicable after the Registration Statement shall have become<br \/>\neffective and the Proxy Statement shall have been cleared by the SEC, the<br \/>\nCompany and Parent shall mail the Joint Proxy\/Prospectus to their respective<br \/>\nshareholders; provided, however, that the parties shall consult and cooperate<br \/>\nwith each other in determining the appropriate time for mailing the Joint<br \/>\nProxy\/Prospectus in light of the date set for the Company Shareholders&#8217; Meeting<br \/>\nand the Parent Stockholders&#8217; Meeting. No filing of, or amendment or supplement<br \/>\nto, the Proxy Statement shall be made by the Company or Parent, and no filing<br \/>\nof, or amendment or supplement to, the Registration Statement shall be made by<br \/>\nParent, in each case, without providing the other party a reasonable opportunity<br \/>\nto review and comment thereon, which comments shall be considered in good faith.<br \/>\nParent and the Company each shall advise the other, promptly after it receives<br \/>\nnotice thereof, of the time when the Registration Statement has become effective<br \/>\nor any supplement or amendment has been filed, of the issuance of any stop<br \/>\norder, the suspension of the qualification of the Parent Common Stock issuable<br \/>\nin connection with the Merger for offering or sale in any jurisdiction, or any<br \/>\nrequest by the SEC for amendment of the Proxy Statement or the Registration<br \/>\nStatement or comments thereon and responses thereto or requests by the SEC for<br \/>\nadditional information.<\/p>\n<p>     (b) The information supplied by Parent for inclusion in the Registration<br \/>\nStatement and the Proxy Statement shall not, at (i) the time the Registration<br \/>\nStatement is declared effective, (ii) the time the Proxy Statement (or any<br \/>\namendment thereof or supplement thereto) is first mailed to the shareholders of<br \/>\nthe Company, (iii) the time the Proxy Statement (or any amendment thereof or<br \/>\nsupplement thereto) is first mailed to stockholders of Parent, (iv) the time of<br \/>\nthe Company Shareholders&#8217; Meeting and (v) the time of the Parent Stockholders&#8217;<br \/>\nMeeting, contain any untrue statement of a material fact or omit to state any<br \/>\nmaterial fact required to be stated therein or necessary in order to make the<br \/>\nstatements therein not misleading. If at any time prior to the Effective Time<br \/>\nany event or circumstance relating to Parent or any of<\/p>\n<p>                                       34<\/p>\n<p>its Subsidiaries, or their respective officers or directors, should be<br \/>\ndiscovered by Parent which should be set forth in an amendment or a supplement<br \/>\nto the Registration Statement or Proxy Statement, Parent shall promptly inform<br \/>\nthe Company. All documents that Parent is responsible for filing with the SEC in<br \/>\nconnection with the transactions contemplated herein will comply as to form and<br \/>\nsubstance in all material respects with the applicable requirements of the<br \/>\nSecurities Act and the rules and regulations thereunder and the Exchange Act and<br \/>\nthe rules and regulations thereunder.<\/p>\n<p>     (c) The information supplied by the Company for inclusion in the<br \/>\nRegistration Statement and the Proxy Statement shall not, at (i) the time the<br \/>\nRegistration Statement is declared effective, (ii) the time the Proxy Statement<br \/>\n(or any amendment thereof or supplement thereto) is first mailed to the<br \/>\nshareholders of the Company, (iii) the time the Proxy Statement (or any<br \/>\namendment thereof or supplement thereto) is first mailed to stockholders of<br \/>\nParent, (iv) the time of the Company Shareholders&#8217; Meeting and (v) the time of<br \/>\nthe Parent Stockholders&#8217; Meeting, contain any untrue statement of a material<br \/>\nfact or omit to state any material fact required to be stated therein or<br \/>\nnecessary in order to make the statements therein not misleading. If at any time<br \/>\nprior to the Effective Time any event or circumstance relating to the Company or<br \/>\nany Company Subsidiary, or their respective officers or directors, should be<br \/>\ndiscovered by the Company which should be set forth in an amendment or a<br \/>\nsupplement to the Registration Statement or Proxy Statement, the Company shall<br \/>\npromptly inform Parent. All documents that the Company is responsible for filing<br \/>\nwith the SEC in connection with the transactions contemplated herein will comply<br \/>\nas to form and substance in all material respects with the applicable<br \/>\nrequirements of the Securities Act and the rules and regulations thereunder and<br \/>\nthe Exchange Act and the rules and regulations thereunder.<\/p>\n<p>     Section 6.2 Shareholders&#8217; Meetings.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>     (a) The Company shall duly call and hold a meeting of its shareholders (the<br \/>\n&#8220;Company Shareholders&#8217; Meeting&#8221;) as promptly as reasonably practicable in<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\naccordance with applicable Law following the date the Registration Statement<br \/>\nbecomes effective and the Proxy Statement is cleared by the SEC and after<br \/>\ncoordination with Parent, provided that the meeting shall be held not later than<br \/>\nfive Business Days prior to the Outside Date (provided that the Company shall<br \/>\nnot be required to hold the Company Shareholders&#8217; Meeting prior to the date of<br \/>\nthe Parent Stockholders&#8217; Meeting), for the purpose of voting upon the adoption<br \/>\nand approval of this Agreement. In connection with the Company Shareholders&#8217;<br \/>\nMeeting and the transactions contemplated hereby, the Company will (i) subject<br \/>\nto applicable Law, use its reasonable best efforts (including postponing or<br \/>\nadjourning the Company Shareholders&#8217; Meeting to obtain a quorum or to solicit<br \/>\nadditional proxies) to obtain the necessary approvals by its shareholders of<br \/>\nthis Agreement, the Merger and the other transactions contemplated hereby and<br \/>\n(ii) otherwise comply with all legal requirements applicable to the Company<br \/>\nShareholders&#8217; Meeting.<\/p>\n<p>     (b) Parent shall duly call and hold a meeting of its stockholders (the<br \/>\n&#8220;Parent Stockholders&#8217; Meeting&#8221;) as promptly as reasonably practicable in<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\naccordance with applicable Law following the date the Registration Statement<br \/>\nbecomes effective and the Proxy Statement is cleared by the SEC and after<br \/>\ncoordination with the Company, provided that the meeting shall be held not later<br \/>\nthan five Business Days prior to the Outside Date (provided that the Parent<br \/>\nshall not be required to hold the Parent Stockholders&#8217; Meeting prior to the date<br \/>\nof the Company<\/p>\n<p>                                       35<\/p>\n<p>Shareholders&#8217; Meeting), for the purpose of voting upon the approval of the Share<br \/>\nIssuance, and Parent shall use its reasonable best efforts to hold the Parent<br \/>\nStockholders&#8217; Meeting as soon as practicable after the date on which the<br \/>\nRegistration Statement becomes effective. In connection with the Parent<br \/>\nStockholders&#8217; Meeting and the transactions contemplated hereby, Parent will (i)<br \/>\nsubject to applicable Law, use its reasonable best efforts (including postponing<br \/>\nor adjourning Parent Stockholders&#8217; Meeting to obtain a quorum or to solicit<br \/>\nadditional proxies) to obtain the necessary approvals by its stockholders of the<br \/>\nShare Issuance and (ii) otherwise comply with all legal requirements applicable<br \/>\nto the Parent Stockholders&#8217; Meeting.<\/p>\n<p>     (c) The Board of Directors of the Company shall recommend approval of this<br \/>\nAgreement and the Merger by the shareholders of the Company (the &#8220;Company<br \/>\n                                                                 &#8212;&#8212;&#8211;<br \/>\nRecommendation&#8221;) and, subject to Section 6.4, shall not withdraw or adversely<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nmodify (or propose to withdraw or adversely modify) such recommendation, and the<br \/>\nJoint Proxy Statement\/Prospectus shall contain such recommendation.<\/p>\n<p>     (d) The Board of Directors of Parent shall recommend the approval of the<br \/>\nShare Issuance by the stockholders of Parent (the &#8220;Parent Recommendation&#8221;) and<br \/>\n                                                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nshall not withdraw or adversely modify (or propose to withdraw or adversely<br \/>\nmodify) such recommendation, and the Joint Proxy Statement\/Prospectus shall<br \/>\ncontain such recommendation.<\/p>\n<p>     Section 6.3 Access to Information; Confidentiality.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n<p>     (a) Except as required pursuant to any confidentiality agreement or similar<br \/>\nagreement or arrangement to which the Company or Parent or any of their<br \/>\nrespective Subsidiaries is a party (which such person shall use reasonable best<br \/>\nefforts to cause the counterparty to waive) from the date of this Agreement to<br \/>\nthe Effective Time, the Company and Parent shall, and shall cause each of its<br \/>\nSubsidiaries and each of their respective directors, officers, employees,<br \/>\naccountants, consultants, legal counsel, investment bankers, advisors, and<br \/>\nagents and other representatives (collectively, &#8220;Representatives&#8221;) to (i)<br \/>\n                                                &#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nprovide to the other party and its respective Representatives access at<br \/>\nreasonable times upon prior notice to the officers, employees, agents,<br \/>\nproperties, offices and other facilities of such party and its Subsidiaries and<br \/>\nto the books and records thereof and (ii) subject to applicable Laws relating to<br \/>\nthe exchange of information, furnish promptly such information concerning the<br \/>\nbusiness, properties, Contracts, assets, liabilities, personnel and other<br \/>\naspects of itself and its Subsidiaries as the other party and its<br \/>\nRepresentatives may reasonably request. No investigation conducted pursuant to<br \/>\nthis Section 6.3(a) shall affect or be deemed to modify or limit any<br \/>\nrepresentation or warranty made in this Agreement.<\/p>\n<p>     (b) With respect to the information disclosed pursuant to this Section 6.3,<br \/>\nthe parties shall comply with, and shall cause their respective Representatives<br \/>\nto comply with, all of their respective obligations under the confidentiality<br \/>\nagreement, dated November 14, 2001, previously executed by the Company and<br \/>\nParent (the &#8220;Confidentiality Agreement&#8221;); provided, however, that the<br \/>\n            &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nrestrictions on Parent and its Subsidiaries, Affiliates and Representatives set<br \/>\nforth in paragraph 8 of the Confidentiality Agreement shall be inapplicable with<br \/>\nrespect to any of the transactions set forth in this Agreement.<\/p>\n<p>                                       36<\/p>\n<p>     Section 6.4 No Solicitation of Transactions.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>     (a) The Company agrees that neither it nor any Company Subsidiary shall,<br \/>\nand that it shall use its reasonable best efforts to cause its and their<br \/>\nRepresentatives not to, directly or indirectly: (i) solicit, initiate,<br \/>\nencourage, knowingly facilitate or induce any inquiry with respect to, or the<br \/>\nmaking, submission or announcement of, any Acquisition Proposal, (ii)<br \/>\nparticipate in any discussions or negotiations regarding, or furnish to any<br \/>\nperson any nonpublic information with respect to, or take any other action to<br \/>\nfacilitate any inquiries or the making of any proposal that constitutes or may<br \/>\nreasonably be expected to lead to, any Acquisition Proposal (except to the<br \/>\nextent specifically permitted pursuant to this Section 6.4), (iii) engage in<br \/>\ndiscussions with any person with respect to any Acquisition Proposal, except to<br \/>\nnotify such person as to the existence of these provisions (except to the extent<br \/>\nspecifically permitted pursuant to this Section 6.4), (iv) approve, endorse or<br \/>\nrecommend any Acquisition Proposal with respect the Company (except to the<br \/>\nextent specifically permitted pursuant to this Section 6.4), or (v) enter into<br \/>\nany letter of intent or similar document or any agreement, commitment or<br \/>\nunderstanding contemplating or otherwise relating to any Acquisition Proposal or<br \/>\na transaction contemplated thereby (except for confidentiality agreements<br \/>\nspecifically permitted pursuant to Section 6.4(c)). The Company shall<br \/>\nimmediately terminate, and shall cause the Company Subsidiaries and its and<br \/>\ntheir Representatives to immediately terminate, all discussions or negotiations,<br \/>\nif any, with any third party with respect to, or any that could reasonably be<br \/>\nexpected to lead to or contemplate the possibility of, an Acquisition Proposal.<br \/>\nThe Company shall immediately demand that each person which has heretofore<br \/>\nexecuted a confidentiality agreement with the Company or any of its Affiliates<br \/>\nor Subsidiaries or any of its or their Representatives with respect to such<br \/>\nperson&#8217;s consideration of a possible Acquisition Proposal to immediately return<br \/>\nor destroy (which destruction shall be certified in writing by such person to<br \/>\nthe Company) all confidential information heretofore furnished by the Company or<br \/>\nany of its Affiliates or Subsidiaries or any of its or their Representatives to<br \/>\nsuch person or any of its Affiliates or Subsidiaries or any of its or their<br \/>\nRepresentatives.<\/p>\n<p>     (b) Promptly after receipt of any Acquisition Proposal or any request for<br \/>\nnonpublic information or inquiry which it reasonably believes could lead to an<br \/>\nAcquisition Proposal, the Company shall provide Parent with written notice of<br \/>\nthe material terms and conditions of such Acquisition Proposal, request or<br \/>\ninquiry, and the identity of the person or group making any such Acquisition<br \/>\nProposal, request or inquiry, and a copy of all written materials provided in<br \/>\nconnection with such Acquisition Proposal, request or inquiry. After receipt of<br \/>\nthe Acquisition Proposal, request or inquiry, the Company shall promptly keep<br \/>\nParent informed in all material respects of the status and details (including<br \/>\nmaterial amendments or proposed material amendments) of any such Acquisition<br \/>\nProposal, request or inquiry and shall promptly provide to Parent a copy of all<br \/>\nwritten materials subsequently provided in connection with such Acquisition<br \/>\nProposal, request or inquiry.<\/p>\n<p>     (c) If the Company receives an Acquisition Proposal which (i) constitutes a<br \/>\nSuperior Proposal or (ii) which the Board of Directors of the Company in good<br \/>\nfaith concludes proposes consideration that is more favorable to the Company&#8217;s<br \/>\nshareholders than the transactions contemplated by this Agreement and which<br \/>\ncould reasonably be expected to result in a Superior Proposal in all other<br \/>\nrespects, the Company shall promptly provide to Parent written notice that shall<br \/>\nstate expressly (A) that it has received an Acquisition Proposal which<\/p>\n<p>                                       37<\/p>\n<p>constitutes a Superior Proposal or which could reasonably be expected to result<br \/>\nin a Superior Proposal, and (B) the identity of the party making such<br \/>\nAcquisition Proposal and the material terms and conditions of the Acquisition<br \/>\nProposal (the &#8220;Superior Proposal Notice&#8221;) and may then take the following<br \/>\n              &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nactions:<\/p>\n<p>         (i)  furnish nonpublic information to the third party making such<br \/>\nAcquisition Proposal, provided, that (A) prior to so furnishing, the Company<br \/>\nreceives from the third party an executed confidentiality agreement containing<br \/>\ncustomary limitations on the use and disclosure of all nonpublic written and<br \/>\noral information furnished to such third party on its behalf and customary<br \/>\nstandstill provisions, and (B) contemporaneously with furnishing any such<br \/>\nnonpublic information to such third party, the Company furnishes a copy of such<br \/>\nnonpublic information to Parent (to the extent such nonpublic information has<br \/>\nnot been previously so furnished); and<\/p>\n<p>         (ii) engage in negotiations with the third party with respect to the<br \/>\nAcquisition Proposal.<\/p>\n<p>     (d) For a period of not less than five Business Days after Parent&#8217;s receipt<br \/>\nfrom the Company of each Superior Proposal Notice, the Company shall, if<br \/>\nrequested by Parent, negotiate in good faith with Parent to revise this<br \/>\nAgreement so that the Acquisition Proposal that constituted a Superior Proposal<br \/>\nno longer constitutes a Superior Proposal.<\/p>\n<p>     (e) In response to the receipt of a Superior Proposal that has not been<br \/>\nwithdrawn and continues to constitute a Superior Proposal after the Company&#8217;s<br \/>\ncompliance with Section 6.4(d), the Board of Directors of the Company may<br \/>\nwithhold or withdraw the Company Recommendation and, in the case of a Superior<br \/>\nProposal that is a tender or exchange offer made directly to its shareholders,<br \/>\nmay recommend that its shareholders accept the tender or exchange offer (any of<br \/>\nthe foregoing actions, whether by the Board of Directors or a committee thereof,<br \/>\na &#8220;Change of Recommendation&#8221;), if both of the following conditions in Sections<br \/>\n  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\n6.4(e)(i) and 6.4(e)(ii) are met:<\/p>\n<p>         (i)  the Company Shareholders&#8217; Meeting has not occurred; and<\/p>\n<p>         (ii) the Board of Directors of the Company has concluded in good faith,<br \/>\nfollowing the receipt of advice of its outside legal counsel, that, in light of<br \/>\nsuch Superior Proposal, the failure of the Board of Directors to effect a Change<br \/>\nof Recommendation would result in a breach of its fiduciary obligations to its<br \/>\nshareholders under applicable Law.<\/p>\n<p>     (f) Notwithstanding anything to the contrary contained in this Agreement,<br \/>\n(i) the obligation of the Company to call, give notice of, convene and hold the<br \/>\nCompany Shareholders&#8217; Meeting and to hold a vote of the Company&#8217;s shareholders<br \/>\non this Agreement and the Merger at the Company Shareholders&#8217; Meeting shall not<br \/>\nbe limited or otherwise affected by the commencement, disclosure, announcement<br \/>\nor submission to it of any Acquisition Proposal (whether or not a Superior<br \/>\nProposal), or by any Change of Recommendation and (ii) in any case in which the<br \/>\nCompany withholds or withdraws the Company Recommendation pursuant to Section<br \/>\n6.4(e), recognizing that special circumstances, as provided in Section<br \/>\n23B.11.030 of the WBCA, exist in light of the provisions of this Section 6.4<br \/>\nand\/or the provisions of the Voting<\/p>\n<p>                                       38<\/p>\n<p>Agreement, the Company shall submit this Agreement and the Merger to a vote of<br \/>\nits shareholders with no recommendation as permitted by Section 23B.11.030(2) of<br \/>\nthe WBCA. The Company agrees that it shall not submit to the vote of its<br \/>\nshareholders any Acquisition Proposal (whether or not a Superior Proposal) or<br \/>\npropose to do so.<\/p>\n<p>     (g) Nothing contained in this Agreement shall be deemed to restrict the<br \/>\nCompany from complying with Rules 14d-9 or 14e-2 under the Exchange Act or be<br \/>\ndeemed to restrict the Company or Parent from making such other disclosures as<br \/>\nmay be required by federal securities laws or applicable State of Washington<br \/>\nfiduciary duties laws.<\/p>\n<p>     (h) Notwithstanding anything to the contrary contained in this Agreement,<br \/>\nthe prohibitions contained in Sections 5.l(j) and 5.1(l) shall not be applicable<br \/>\nwith respect to a Person who has submitted a Superior Proposal to the Company.<\/p>\n<p>     Section 6.5 Appropriate Action; Consents; Filings.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>     (a) Subject to the proviso contained in Section 6.5(b)(ii), the Company and<br \/>\nParent shall use their reasonable best efforts to (i) take, or cause to be<br \/>\ntaken, all appropriate action, and do, or cause to be done, all things<br \/>\nnecessary, proper or advisable under applicable Law or otherwise to consummate<br \/>\nand make effective the transactions contemplated by this Agreement as promptly<br \/>\nas practicable, (ii) obtain from any Governmental Entities any consents,<br \/>\nlicenses, permits, waivers, approvals, authorizations or orders required (A) to<br \/>\nbe obtained or made by Parent or the Company or any of their Subsidiaries, (B)<br \/>\nto avoid any action or proceeding by any Governmental Entity (including, without<br \/>\nlimitation, those in connection with the HSR Act and antitrust and competition<br \/>\nLaws of any other applicable jurisdiction), in connection with the<br \/>\nauthorization, execution and delivery of this Agreement and the consummation of<br \/>\nthe transactions contemplated herein, including, without limitation, the Merger,<br \/>\nand (C) to prevent a Company Material Adverse Effect from occurring prior to or<br \/>\nafter the Effective Time or a Parent Material Adverse Effect from occurring<br \/>\nafter the Effective Time, and (iii) make all necessary filings, and thereafter<br \/>\nmake any other required submissions, with respect to this Agreement and the<br \/>\nMerger required under (A) the Securities Act and the Exchange Act, and any other<br \/>\napplicable federal or state securities Laws, (B) the HSR Act and antitrust and<br \/>\ncompetition Laws of any other applicable jurisdiction and (C) any other<br \/>\napplicable Law. Parent and the Company shall cooperate with each other in<br \/>\nconnection with the making of all filings referenced in the preceding sentence,<br \/>\nincluding providing copies of all such documents to the non-filing party and its<br \/>\nadvisors prior to filing and, if requested, to accept all reasonable additions,<br \/>\ndeletions or changes suggested in connection therewith. The Company and Parent<br \/>\nshall have the right to review in advance, and to the extent practicable each<br \/>\nshall consult the other on, all the information relating to the Company and the<br \/>\nCompany Subsidiaries or Parent and its Subsidiaries, as the case may be, that<br \/>\nappears in any filing made with, or written materials submitted to, any third<br \/>\nparty and\/or any Governmental Entity in connection with the Merger and the other<br \/>\ntransactions contemplated by this Agreement. Parent and the Company may, as each<br \/>\ndeems reasonably advisable and necessary, designate any competitively sensitive<br \/>\ninformation provided to the other under this Section 6.5(a) as &#8220;outside counsel<br \/>\nonly.&#8221; Such information shall be given only to outside counsel of the recipient.<br \/>\nIn addition, Parent and the Company may redact any information from such<br \/>\ndocuments shared with the other party or its counsel that is not pertinent to<br \/>\nthe subject matter of the filing or submission.<\/p>\n<p>                                       39<\/p>\n<p>     (b) Without limiting Section 6.5(a), Parent and the Company shall:<\/p>\n<p>         (i) each use its reasonable best efforts to avoid the entry of, or to<br \/>\nhave vacated or terminated, any decree, order, or judgment that would restrain,<br \/>\nprevent or delay the Closing, on or before the Outside Date, including defending<br \/>\nthrough litigation on the merits any claim asserted in any court by any person;<br \/>\nand<\/p>\n<p>         (ii) each use its reasonable best efforts to avoid or eliminate each<br \/>\nand every impediment under any antitrust, competition or trade regulation Law<br \/>\nthat may be asserted by any Governmental Entity with respect to the Merger so as<br \/>\nto enable the Closing to occur as soon as reasonably possible (and in any event<br \/>\nno later than the Outside Date), including implementing, contesting or resisting<br \/>\nany litigation before any court or quasi-judicial administrative tribunal<br \/>\nseeking to restrain or enjoin the Merger; provided, however, that nothing in<br \/>\nthis Agreement shall require any of Parent and its Subsidiaries or the Company<br \/>\nand its Subsidiaries to commit to any divestitures, licenses or hold separate or<br \/>\nsimilar arrangements with respect to its assets or conduct of business<br \/>\narrangements, whether as a condition to obtaining any approval from a<br \/>\nGovernmental Entity or any other person or for any other reason, if, in any such<br \/>\ncase, such divestiture, license, holding separate or arrangement (x) is not<br \/>\nconditioned upon the consummation of the Merger or (y) would, individually or in<br \/>\nthe aggregate, have a Parent Material Adverse Effect (including, for purposes of<br \/>\nthis clause, the Surviving Corporation and its Subsidiaries) after giving effect<br \/>\nto the Merger.<\/p>\n<p>     (c) Subject to the proviso contained in Section 6.5(b)(ii) and the proviso<br \/>\ncontained in the following sentence of this Section 6.5(c), the Company and<br \/>\nParent shall give (or shall cause their respective Subsidiaries to give) any<br \/>\nnotices to third parties, and use, and cause their respective Subsidiaries to<br \/>\nuse, reasonable best efforts to obtain any non-governmental third party<br \/>\nconsents, (i) necessary, proper or advisable to consummate the transactions<br \/>\ncontemplated in this Agreement, (ii) required to be disclosed in the Company<br \/>\nDisclosure Letter or the Parent Disclosure Letter, as applicable, or (iii)<br \/>\nrequired to prevent a Company Material Adverse Effect from occurring prior to or<br \/>\nafter the Effective Time or a Parent Material Adverse Effect from occurring<br \/>\nafter the Effective Time. In the event that either party shall fail to obtain<br \/>\nany third party consent described in the first sentence of this Section 6.5(c),<br \/>\nsuch party shall use reasonable best efforts, and shall take any such actions<br \/>\nreasonably requested by the other party hereto, to minimize any adverse effect<br \/>\nupon the Company and Parent, their respective Subsidiaries, and their respective<br \/>\nbusinesses resulting, or which could reasonably be expected to result after the<br \/>\nEffective Time, from the failure to obtain such consent; provided that no<br \/>\nobligation to make a material payment or grant a material right not conditioned<br \/>\nupon the consummation of the Merger shall be imposed by this Section 6.5(c).<\/p>\n<p>     (d) From the date of this Agreement until the Effective Time, each party<br \/>\nshall promptly notify the other party in writing of any pending or, to the<br \/>\nKnowledge of the Company or Parent, as appropriate, threatened action, suit,<br \/>\narbitration or other proceeding or investigation by any Governmental Entity or<br \/>\nany other person (i) challenging or seeking damages in connection with the<br \/>\nMerger or the conversion of Company Common Stock into Parent Common Stock<br \/>\npursuant to the Merger or (ii) seeking to restrain or prohibit the consummation<br \/>\nof the Merger or otherwise limit the right of Parent or its Subsidiaries to own<br \/>\nor operate all or any portion of the businesses or assets of the Company or its<br \/>\nSubsidiaries.<\/p>\n<p>                                       40<\/p>\n<p>     Section 6.6   Certain Notices. From and after the date of this Agreement<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nuntil the Effective Time, each party hereto shall promptly notify the other<br \/>\nparty hereto of (a) the occurrence, or non-occurrence, of any event that would<br \/>\nbe likely to cause any condition to the obligations of any party to effect the<br \/>\nMerger and the other transactions contemplated by this Agreement not to be<br \/>\nsatisfied or (b) the failure of the Company or Parent, as the case may be, to<br \/>\ncomply with or satisfy any covenant, condition or agreement to be complied with<br \/>\nor satisfied by it pursuant to this Agreement which would reasonably be expected<br \/>\nto result in any condition to the obligations of any party to effect the Merger<br \/>\nand the other transactions contemplated by this Agreement not to be satisfied;<br \/>\nprovided, however, that the delivery of any notice pursuant to this Section 6.6<br \/>\nshall not cure any breach of any representation or warranty, the failure to<br \/>\ncomply with any covenant, the failure to meet any condition or otherwise limit<br \/>\nor affect the remedies available hereunder to the party receiving such notice.<\/p>\n<p>     Section 6.7   Public Announcements. Parent and the Company will consult<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nwith each other before issuing, and provide each other the opportunity to review<br \/>\nand make reasonable comment upon, any press release or making any public<br \/>\nstatement with respect to this Agreement and the transactions contemplated<br \/>\nhereby and, except as may be required by applicable Law or any listing agreement<br \/>\nwith Nasdaq, will not issue any such press release or make any such public<br \/>\nstatement prior to such consultation; provided, however, that each of Parent and<br \/>\nthe Company may make any public statement in response to specific questions by<br \/>\nthe press, analysts, investors or those attending industry conferences or<br \/>\nfinancial analyst conference calls, so long as any such statements are not<br \/>\ninconsistent with previous press releases, public disclosures or public<br \/>\nstatements made jointly by Parent and the Company and do not reveal non-public<br \/>\ninformation regarding the other party.<\/p>\n<p>     Section 6.8   Nasdaq Listing. Parent shall use reasonable best efforts (a)<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nto cause the Parent Common Stock to be issued in the Merger to be approved for<br \/>\nlisting upon the Effective Time on Nasdaq or on such national securities<br \/>\nexchange as the Parent Common Stock is listed and (b) to cause the Parent Common<br \/>\nStock issued upon the exercise of converted Company Options to be approved for<br \/>\nlisting on Nasdaq or on such national securities exchange as Parent Common Stock<br \/>\nis listed.<\/p>\n<p>    Section 6.9   Employee Benefit Matters.<br \/>\n                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>    (a) For a period of at least two years following the Effective Time, Parent<br \/>\nshall provide employee benefits (excluding any benefits attributable to equity<br \/>\nbased plans or grants) to the employees and former employees of the Company and<br \/>\ntheir respective Subsidiaries (&#8220;New Parent Employees&#8221;) that are no less<br \/>\n                                &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nfavorable in the aggregate than those provided to such persons in effect on the<br \/>\ndate hereof. Nothing herein shall require Parent to continue any particular<br \/>\nCompany Benefit Plan or prevent the amendment or termination thereof (subject to<br \/>\nthe maintenance, in the aggregate, of the benefits as provided in the preceding<br \/>\nsentence); provided, however, that Parent shall not take any action (by way of<br \/>\namendment, termination or otherwise) which is in violation of the terms of any<br \/>\nCompany Benefit Plan or applicable Law.<\/p>\n<p>     (b) With respect to each benefit plan of Parent (&#8220;Parent Benefit Plan&#8221;) in<br \/>\n                                                       &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nwhich New Parent Employees subsequently participate, for purposes of<br \/>\ndetermining vesting and entitlement to benefits, including for severance<br \/>\nbenefits and vacation entitlement (but not for<\/p>\n<p>                                       41<\/p>\n<p>accrual of pension benefits), service with the Company (or predecessor employers<br \/>\nto the extent the Company provides past service credit) shall be treated as<br \/>\nservice with Parent; provided, that such service shall not be recognized to the<br \/>\nextent that such recognition would result in a duplication of benefits or to the<br \/>\nextent that such service was not recognized under the applicable Company Benefit<br \/>\nPlan. Such service also shall apply for purposes of satisfying any waiting<br \/>\nperiods, evidence of insurability requirements, or the application of any<br \/>\npre-existing condition limitations. Each Parent Benefit Plan shall waive<br \/>\npre-existing condition limitations to the same extent waived under the<br \/>\napplicable Company Benefit Plan. New Parent Employees shall be given credit for<br \/>\namounts paid under a corresponding benefit plan during the same period for<br \/>\npurposes of applying deductibles, co-payments and out-of-pocket maximums as<br \/>\nthough such amounts had been paid in accordance with the terms and conditions of<br \/>\nthe Parent Benefit Plan for the plan year in which the Effective Time occurs.<\/p>\n<p>     (c) At the request of Parent, the Company shall terminate any and all<br \/>\n401(k) plans of the Company, effective not later than the day immediately<br \/>\npreceding the Closing Date. In the event that Parent requests that such 401(k)<br \/>\nplan(s) be terminated, the Company shall provide Parent with evidence that such<br \/>\n401(k) plan(s) have been terminated pursuant to resolution of Company&#8217;s Board of<br \/>\nDirectors (the form and substance of which shall be subject to review and<br \/>\napproval by Parent) not later than the day immediately preceding the Closing<br \/>\nDate.<\/p>\n<p>     Section 6.10   Indemnification of Directors and Officers.<br \/>\n                    &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<\/p>\n<p>     (a) Parent shall, and shall cause the Surviving Corporation to, indemnify<br \/>\nand hold harmless, and provide advancement of expenses to, all past and present<br \/>\ndirectors, officers and employees of the Company or any of its Subsidiaries to<br \/>\nthe fullest extent permitted by Law for acts or omissions occurring at or prior<br \/>\nto the Effective Time (including for acts or omissions occurring in connection<br \/>\nwith the approval of this Agreement and the consummation of the transactions<br \/>\ncontemplated hereby) in their capacities as such.<\/p>\n<p>     (b) For six years from the Effective Time, Parent shall, or shall cause the<br \/>\nSurviving Corporation to, cause to be maintained in effect for the benefit of<br \/>\nthe Company&#8217;s current directors and officers an insurance and indemnification<br \/>\npolicy that provides coverage for acts or omissions occurring prior to the<br \/>\nEffective Time (the &#8220;D&amp;O Insurance&#8221;) covering each such person currently covered<br \/>\n                     &#8212;&#8212;&#8212;&#8212;-<br \/>\nby the officers&#8217; and directors&#8217; liability insurance policies of the Company on<br \/>\nterms with respect to coverage and in amounts no less favorable than those of<br \/>\nthe Company&#8217;s policies in effect on the date hereof; provided, however, that the<br \/>\nSurviving Corporation shall not be required to pay an annual premium for the D&amp;O<br \/>\nInsurance in excess of 200% of the estimated premium for the 2002 fiscal year,<br \/>\nwhich premium the Company presently expects to be approximately $1,850,000.<\/p>\n<p>     (c) Parent shall, and shall cause the Surviving Corporation to, cause to be<br \/>\nmaintained in effect in the Surviving Corporation&#8217;s (or any successor&#8217;s)<br \/>\nArticles of Incorporation and Bylaws provisions with respect to indemnification<br \/>\nand advancement of expenses that are at least as favorable to the intended<br \/>\nbeneficiaries as those contained in the Company Articles and the Company Bylaws<br \/>\nas in effect on the date hereof.<\/p>\n<p>                                       42<\/p>\n<p>     (d) Parent agrees to honor (and hereby guarantees the Surviving<br \/>\nCorporation&#8217;s performance under) all indemnification agreements entered into by<br \/>\nthe Company or any Company Subsidiary. In the event that Parent or the Surviving<br \/>\nCorporation or any of their respective successors or assigns (i) consolidates<br \/>\nwith or merges into any other person and is not the continuing or surviving<br \/>\ncorporation or entity of such consolidation or merger or (ii) transfers or<br \/>\nconveys all or substantially all its properties and assets to any person, then,<br \/>\nand in each such case, Parent shall cause proper provisions to be made so that<br \/>\nthe successors and assigns of the Parent or the Surviving Corporation, as the<br \/>\ncase may be, assume the obligations set forth in this Section 6.10. The<br \/>\nobligations of Parent and the Surviving Corporation under this Section 6.10<br \/>\nshall not be terminated or modified in such a manner as to adversely affect any<br \/>\nindemnitee to whom this Section 6.10 applies without the express written consent<br \/>\nof such affected indemnitee (it being expressly agreed that the indemnitees to<br \/>\nwhom this Section 6.10 applies shall be third party beneficiaries of this<br \/>\nSection 6.10).<\/p>\n<p>     Section 6.11   Plan of Reorganization.  This Agreement is intended to<br \/>\n                    &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nconstitute a &#8220;plan of reorganization&#8221; within the meaning of Treasury Regulation<br \/>\nSection 1.368-2(g).<\/p>\n<p>     Section 6.12   Affiliate Letters. The Company shall, promptly after the<br \/>\n                    &#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\ndate hereof and prior to the mailing of the Joint Proxy\/Prospectus, deliver to<br \/>\nParent a list setting forth the names of all persons the Company expects to be,<br \/>\nat the time of the Company Shareholders&#8217; Meeting, &#8220;affiliates&#8221; of the Company<br \/>\nfor purposes of Rule 145 under the Securities Act. The Company shall furnish<br \/>\nsuch information and documents as Parent may reasonably request for the purpose<br \/>\nof reviewing the list. The Company shall use reasonable best efforts to cause<br \/>\neach person who is identified as an affiliate in the list furnished or<br \/>\nsupplemented pursuant to this Section 6.12 to execute a written agreement,<br \/>\npromptly following the date hereof, in substantially the form of Exhibit 6.12<br \/>\nhereto.<\/p>\n<p>     Section 6.13   Section 16 Matters. Prior to the Effective Time: (a) the<br \/>\n                    &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nBoard of Directors of Parent, or an appropriate committee of non-employee<br \/>\ndirectors thereof, shall adopt a resolution consistent with the interpretive<br \/>\nguidance of the SEC so that the acquisition by any officer or director of the<br \/>\nCompany who may become a covered person of Parent for purposes of Section 16 of<br \/>\nthe Exchange Act (together with the rules and regulations thereunder, &#8220;Section<br \/>\n                                                                       &#8212;&#8212;-<br \/>\n16&#8221;), of shares of Parent Common Stock or options to purchase shares of Parent<br \/>\n&#8212;<br \/>\nCommon Stock pursuant to this Agreement and the Merger shall be an exempt<br \/>\ntransaction for purposes of Section 16; and (b) the Board of Directors of the<br \/>\nCompany or an appropriate committee of non-employee directors thereof, shall<br \/>\nadopt a resolution consistent with the interpretive guidance of the SEC so that<br \/>\nthe disposition by any officer or director of the Company who is a covered<br \/>\nperson of the Company for purposes of Section 16 of shares of Company Common<br \/>\nStock or Company Options pursuant to this Agreement and the Merger shall be an<br \/>\nexempt transaction for purposes of Section 16.<\/p>\n<p>     Section 6.14   Stock Award Matters.<br \/>\n                    &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>     (a) The Company shall, and shall cause the administrator(s) of each of the<br \/>\nCompany Stock Option Plans and the ESPP to, take any and all actions necessary<br \/>\n(under the applicable Company Stock Option Plan and otherwise) to (i) cause the<br \/>\nCompany Options to be treated in accordance with Section 2.4 hereof, including,<br \/>\nwithout limitation, amending the<\/p>\n<p>                                       43<\/p>\n<p>Company Stock Option Plans and, if necessary or desirable, obtaining the consent<br \/>\nof the optionholders to such treatment; and (ii) cause the stock purchase rights<br \/>\noutstanding under the ESPP to be assumed and converted into rights to purchase<br \/>\nParent Common Stock pursuant to Section 2.5 in such manner as will not result in<br \/>\nacceleration of the exercise of stock purchase rights under the ESPP.<\/p>\n<p>     (b) Promptly after the Effective Time, Parent shall file one or more<br \/>\nregistration statements on Form S-3 or Form S-8, as the case may be (or any<br \/>\nother successor or other appropriate forms), with respect to the shares of<br \/>\nParent Common Stock subject to options and purchase rights issued pursuant to<br \/>\nSections 2.4 and 2.5 and shall maintain the effectiveness of such registration<br \/>\nstatement or registration statements (and maintain the current status of the<br \/>\nprospectus or prospectuses contained therein) for so long as such options remain<br \/>\noutstanding.<\/p>\n<p>     Section 6.15   Restructure of Transaction. In the event that either of<br \/>\n                    &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nLatham &amp; Watkins, counsel to Parent, or Skadden, Arps, Slate, Meagher &amp; Flom<br \/>\nLLP, counsel to the Company, is unable to render its opinion pursuant to Section<br \/>\n7.2(c) or Section 7.3(c), respectively, the structure of the Merger shall be<br \/>\nrevised to provide for the merger of the Company with and into Merger Sub with<br \/>\nMerger Sub being the surviving entity in such Merger (the &#8220;Forward Subsidiary<br \/>\n                                                           &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nMerger&#8221;), subject to the approval of each of the Company and Parent which<br \/>\n&#8212;&#8212;<br \/>\napproval shall not be unreasonably withheld or delayed; provided, that if a<br \/>\nForward Subsidiary Merger structure would not result in each of Latham &amp; Watkins<br \/>\nor Skadden, Arps, Slate, Meagher &amp; Flom LLP being able to render such respective<br \/>\nopinions, the Company and Parent shall negotiate in good faith to revise the<br \/>\nstructure of the business combination between the Company and Parent such that<br \/>\neach of Latham &amp; Watkins and Skadden, Arps, Slate, Meagher &amp; Flom LLP will be<br \/>\nable to render such opinion; provided, further, that no such revision to the<br \/>\nstructure of the Merger shall (a) result in any change in the Merger<br \/>\nConsideration, (b) be materially adverse to the interests of Parent, the<br \/>\nCompany, Merger Sub, the holders of shares of Parent Common Stock or the holders<br \/>\nof shares of Company Common Stock or (c) unreasonably impede or delay<br \/>\nconsummation of the Merger. If the structure of the Merger is so revised, this<br \/>\nAgreement shall be amended by the parties as appropriate to give effect to the<br \/>\nrevised structure of the Merger with each party executing a written amendment to<br \/>\nthis Agreement as necessary to reflect the foregoing.<\/p>\n<p>                                   ARTICLE 7.<br \/>\n                               CLOSING CONDITIONS<\/p>\n<p>     Section 7.1   Conditions to Obligations of Each Party Under This Agreement.<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nThe respective obligations of each party to effect the Merger and the other<br \/>\ntransactions contemplated herein shall be subject to the satisfaction at or<br \/>\nprior to the Effective Time of the following conditions, any or all of which may<br \/>\nbe waived, in whole or in part, to the extent permitted by applicable Law:<\/p>\n<p>     (a) Effectiveness of the Registration Statement. The Registration Statement<br \/>\nshall have been declared effective by the SEC under the Securities Act. No stop<br \/>\norder suspending the effectiveness of the Registration Statement shall have been<br \/>\nissued by the SEC and no proceedings for that purpose shall have been initiated<br \/>\nor, to the Knowledge of Parent or the Company, threatened by the SEC.<\/p>\n<p>                                       44<\/p>\n<p>     (b) Shareholder and Stockholder Approval. The Company Shareholder Approval<br \/>\nand the Parent Stockholder Approval shall have been obtained.<\/p>\n<p>     (c) No Order. No Governmental Entity, nor any federal or state court of<br \/>\ncompetent jurisdiction shall have enacted, issued, promulgated, enforced or<br \/>\nentered any statute, rule, regulation, executive order, decree, judgment or<br \/>\ninjunction or order (whether temporary, preliminary or permanent), in any case<br \/>\nwhich is in effect and which prevents or prohibits consummation of the Merger.<\/p>\n<p>     (d) Consents and Approvals. Other than the filing provided for under<br \/>\nSection 1.2 and filings pursuant to the HSR Act, all consents, approvals and<br \/>\nauthorizations of any Governmental Entity required of Parent, the Company or any<br \/>\nof their Subsidiaries to consummate the Merger, the failure of which to be<br \/>\nobtained or taken, individually or in the aggregate, would have a Parent<br \/>\nMaterial Adverse Effect (determined, for purposes of this clause, after giving<br \/>\neffect to the Merger), shall have been obtained.<\/p>\n<p>     (e) HSR Act. The applicable waiting periods, together with any extensions<br \/>\nthereof, under the HSR Act shall have expired or been terminated.<\/p>\n<p>     (f) Nasdaq Listing. The shares of Parent Common Stock issuable to the<br \/>\nCompany&#8217;s shareholders in the Merger and such other shares of Parent Common<br \/>\nStock to be reserved for issuance in connection with the Merger shall have been<br \/>\napproved for listing on Nasdaq or on such national securities exchange as Parent<br \/>\nCommon Stock is then listed, subject to official notice of issuance.<\/p>\n<p>     (g) Litigation. There shall not be instituted or pending any action,<br \/>\nlitigation or proceeding by any Governmental Entity (i) seeking to prohibit,<br \/>\nrestrain or otherwise interfere with the Merger or the ownership or operation by<br \/>\nParent or any of its Subsidiaries of all or any portion of the business or<br \/>\nassets of the Company or Parent or any of their Subsidiaries or to compel Parent<br \/>\nor any of its Subsidiaries to dispose of or hold separate all or any portion of<br \/>\nthe business or assets of the Company or Parent or any of their respective<br \/>\nSubsidiaries, or (ii) seeking divestiture of any shares of Company Common Stock<br \/>\n(or shares of stock of the Surviving Corporation) or seeking to impose or<br \/>\nconfirm limitations on the ability of Parent to effectively exercise full rights<br \/>\nof ownership of the shares of Company Common Stock (or shares of stock of the<br \/>\nSurviving Corporation), including the right to vote any securities on any<br \/>\nmatters properly presented to shareholders, in the case of clause (i) or (ii),<br \/>\nwhich would, or would reasonably be expected to, have a Parent Material Adverse<br \/>\nEffect (determined, for purposes of this clause, after giving effect to the<br \/>\nMerger).<\/p>\n<p>     Section 7.2 Additional Conditions to Obligations of Parent and Merger Sub.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nThe obligations of Parent and Merger Sub to effect the Merger and the other<br \/>\ntransactions contemplated herein are also subject to the following conditions:<\/p>\n<p>     (a) Representations and Warranties. The representations and warranties of<br \/>\nthe Company contained in this Agreement shall be true and correct (without<br \/>\ngiving effect to any limitation as to &#8220;materiality&#8221; or &#8220;Company Material Adverse<br \/>\nEffect&#8221; set forth therein) at and as of the Effective Time as if made at and as<br \/>\nof such time (except to the extent expressly made as of<\/p>\n<p>                                       45<\/p>\n<p>an earlier date, in which case as of such earlier date), except where the<br \/>\nfailure of such representations and warranties to be true and correct (without<br \/>\ngiving effect to any limitation as to &#8220;materiality&#8221; or &#8220;Company Material Adverse<br \/>\nEffect&#8221; set forth therein) would not, individually or in the aggregate, result<br \/>\nin a Company Material Adverse Effect. Parent shall have received a certificate<br \/>\nsigned by an executive officer of the Company on its behalf to the foregoing<br \/>\neffect.<\/p>\n<p>     (b) Agreements and Covenants. The Company shall have performed or complied<br \/>\nin all material respects with all agreements and covenants required by this<br \/>\nAgreement to be performed or complied with by it on or prior to the Effective<br \/>\nTime. Parent shall have received a certificate of an executive officer of the<br \/>\nCompany to that effect.<\/p>\n<p>     (c) Parent Tax Opinion. Parent shall have received the opinion of Latham &amp; Watkins, dated the date of the Effective Time, to the effect that the Merger<br \/>\nwill be treated for Federal income Tax purposes as a reorganization within the<br \/>\nmeaning of Section 368(a) of the Code. In rendering such opinion, Latham &amp; Watkins shall receive and rely upon representations contained in letters of<br \/>\nParent and the Company to be delivered as of the Effective Time substantially in<br \/>\nthe forms attached hereto as Exhibits 7.2(c)(i) and 7.2(c)(ii), respectively.<br \/>\nThe opinion referred to in this Section 7.2(c) shall not be waivable after<br \/>\nreceipt of the Company Shareholder Approval or the Parent Stockholder Approval<br \/>\nreferred to in Section 7.1(b), unless further stockholder approval is obtained<br \/>\nwith appropriate disclosure.<\/p>\n<p>     (d) AHP Agreements. The AHP Agreements shall be in full force and effect,<br \/>\nand no authorized officer of AHP shall have notified Parent in writing of, and<br \/>\nAHP shall not have publicly announced, AHP&#8217;s intention to repudiate such<br \/>\nagreements.<\/p>\n<p>     Section 7.3 Additional Conditions to Obligations of the Company. The<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nobligation of the Company to effect the Merger and the other transactions<br \/>\ncontemplated in this Agreement is also subject to the following conditions:<\/p>\n<p>     (a) Representations and Warranties. The representations and warranties of<br \/>\nParent contained in this Agreement shall be true and correct (without giving<br \/>\neffect to any limitation as to &#8220;materiality&#8221; or &#8220;Parent Material Adverse Effect&#8221;<br \/>\nset forth therein) at and as of the Effective Time as if made at and as of such<br \/>\ntime (except to the extent expressly made as of an earlier date, in which case<br \/>\nas of such earlier date), except where the failure of such representations and<br \/>\nwarranties to be true and correct (without giving effect to any limitation as to<br \/>\n&#8220;materiality&#8221; or &#8220;Parent Material Adverse Effect&#8221; set forth therein) would not,<br \/>\nindividually or in the aggregate, result in a Parent Material Adverse Effect.<br \/>\nThe Company shall have received a certificate signed by an executive officer of<br \/>\nParent on its behalf to the foregoing effect.<\/p>\n<p>     (b) Agreements and Covenants. Parent shall have performed or complied in<br \/>\nall material respects with all agreements and covenants required by this<br \/>\nAgreement to be performed or complied with by it on or prior to the Effective<br \/>\nTime. The Company shall have received a certificate of an executive officer of<br \/>\nParent to that effect.<\/p>\n<p>     (c) Company Tax Opinion. The Company shall have received the opinion of<br \/>\nSkadden, Arps, Slate, Meagher &amp; Flom LLP, dated the date of the Effective Time,<br \/>\nto the effect that the Merger will be treated for federal income Tax purposes as<br \/>\na reorganization within the<\/p>\n<p>                                       46<\/p>\n<p>meaning of Section 368(a) of the Code. In rendering such opinion, Skadden, Arps,<br \/>\nSlate, Meagher &amp; Flom LLP shall receive and rely upon representations contained<br \/>\nin letters of Parent and the Company to be delivered as of the Effective Time<br \/>\nsubstantially in the form attached hereto as Exhibits 7.2(c)(i) and 7.2(c)(ii),<br \/>\nrespectively. The opinion referred to in this Section 7.3(c) shall not be<br \/>\nwaivable after receipt of the Company Shareholder Approval or the Parent<br \/>\nStockholder Approval referred to in Section 7.1(b), unless further stockholder<br \/>\napproval is obtained with appropriate disclosure.<\/p>\n<p>                                   ARTICLE 8.<br \/>\n                        TERMINATION, AMENDMENT AND WAIVER<\/p>\n<p>     Section 8.1 Termination. This Agreement may be terminated at any time prior<br \/>\n                 &#8212;&#8212;&#8212;&#8211;<br \/>\nto the Effective Time, by action taken or authorized by the Board of Directors<br \/>\nof the terminating party or parties, whether before or after approval of the<br \/>\nmatters presented in connection with the Merger by the shareholders of the<br \/>\nCompany or the stockholders of Parent:<\/p>\n<p>     (a) By mutual written consent of Parent and the Company, which consent<br \/>\nshall have been approved by action of their respective Boards of Directors;<\/p>\n<p>     (b) By written notice of either the Company or Parent, if the Merger shall<br \/>\nnot have been consummated prior to September 30, 2002 (such date, as it may be<br \/>\nextended as provided below, shall be referred to herein as the &#8220;Outside Date&#8221;);<br \/>\n                                                               &#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nprovided, however, that such date may, from time to time, be extended by either<br \/>\nparty (by written notice thereof to the other party) up to and including<br \/>\nDecember 31, 2002 in the event all conditions to effect the Merger other than<br \/>\none or more conditions set forth in Sections 7.1(c), 7.1(d), 7.1(e) or 7.1(g)<br \/>\n(the &#8220;Regulatory Conditions&#8221;) have been or are capable of being satisfied at the<br \/>\ntime of each such extension and the Regulatory Conditions have been or are<br \/>\nreasonably capable of being satisfied on or prior to December 31, 2002; provided<br \/>\nfurther that the right to terminate this Agreement under this Section 8.1(b)<br \/>\nshall not be available to any party whose failure to fulfill any obligation<br \/>\nunder this Agreement has been the cause of, or results in, the failure of the<br \/>\nMerger to occur on or before such date;<\/p>\n<p>     (c) By written notice of either the Company or Parent, if any Governmental<br \/>\nEntity shall have issued an order, decree or ruling or taken any other action<br \/>\npermanently restraining, enjoining or otherwise prohibiting the Merger, and such<br \/>\norder, decree, ruling or other action shall have become final and nonappealable<br \/>\n(which order, decree, ruling or other action the parties shall have used their<br \/>\nreasonable best efforts to resist, resolve or lift, as applicable, subject to<br \/>\nSection 6.5);<\/p>\n<p>     (d) By written notice of Parent, if (i) the Board of Directors of the<br \/>\nCompany shall have withdrawn or adversely modified, or shall have resolved to<br \/>\nwithdraw or adversely modify, the Company Recommendation; (ii) the Board of<br \/>\nDirectors of the Company shall have approved or recommended, or shall have<br \/>\nresolved to approve or recommend, to the shareholders of the Company, an<br \/>\nAcquisition Proposal other than that contemplated by this Agreement; or (iii)<br \/>\nthe Company fails to call or hold the Company Shareholders&#8217; Meeting by the fifth<br \/>\nday prior to the Outside Date;<\/p>\n<p>                                       47<\/p>\n<p>     (e) By written notice of the Company, if (i) the Board of Directors of<br \/>\nParent shall have withdrawn or adversely modified, or shall have resolved to<br \/>\nwithdraw or adversely modify, the Parent Recommendation or (ii) Parent fails to<br \/>\ncall or hold the Parent Stockholders&#8217; Meeting by the fifth day prior to the<br \/>\nOutside Date;<\/p>\n<p>     (f) By written notice of Parent, if there has been a breach by the Company<br \/>\nof any representation, warranty, covenant or agreement contained in this<br \/>\nAgreement which (i) would result in a failure of a condition set forth in<br \/>\nSection 7.2(a) or 7.2(b) and (ii) cannot be cured prior to the Outside Date,<br \/>\nprovided that Parent shall have given the Company written notice, delivered at<br \/>\nleast twenty days prior to such termination, stating Parent&#8217;s intention to<br \/>\nterminate this Agreement pursuant to this Section 8.1(f) and the basis for such<br \/>\ntermination;<\/p>\n<p>     (g) By written notice of the Company, if there has been a breach by Parent<br \/>\nof any representation, warranty, covenant or agreement contained in this<br \/>\nAgreement which (i) would result in a failure of a condition set forth in<br \/>\nSection 7.3(a) or 7.3(b) and (ii) cannot be cured prior to the Outside Date,<br \/>\nprovided that the Company shall have given Parent written notice, delivered at<br \/>\nleast twenty days prior to such termination, stating the Company&#8217;s intention to<br \/>\nterminate this Agreement pursuant to this Section 8.1(g) and the basis for such<br \/>\ntermination; or<\/p>\n<p>     (h) By written notice of either Parent or the Company if (i) the Company<br \/>\nShareholder Approval shall not have been obtained at the Company Shareholders&#8217;<br \/>\nMeeting duly convened therefor (or at any adjournment or postponement thereof)<br \/>\nat which a quorum is present and the vote to adopt and approve this Agreement<br \/>\nand the Merger is taken, or (ii) the Parent Stockholder Approval shall not have<br \/>\nbeen obtained at the Parent Stockholders&#8217; Meeting duly convened therefor (or at<br \/>\nany adjournment or postponement thereof) at which a quorum is present and the<br \/>\nvote to approve the Share Issuance is taken.<\/p>\n<p>     Section 8.2 Effect of Termination.<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>     (a) Limitation on Liability. In the event of termination of this Agreement<br \/>\nby either the Company or Parent as provided in Section 8.1, this Agreement shall<br \/>\nforthwith become void and there shall be no liability or obligation on the part<br \/>\nof Parent, Merger Sub or the Company or their respective Subsidiaries, officers<br \/>\nor directors, except with respect to Sections 6.3(b) and 8.2 and Article 9 and<br \/>\nwith respect to any liabilities or damages incurred or suffered by a party as a<br \/>\nresult of the willful and material breach by the other party of any of its<br \/>\nrepresentations, warranties, covenants or other agreements set forth in this<br \/>\nAgreement.<\/p>\n<p>     (b) Parent Expenses. Parent and the Company agree that if this Agreement is<br \/>\nterminated pursuant to Sections 8.1(f), then the Company shall pay Parent an<br \/>\namount equal to the sum of Parent&#8217;s Expenses up to an amount equal to $15<br \/>\nmillion.<\/p>\n<p>     (c) Company Expenses. Parent and the Company agree that if this Agreement<br \/>\nis terminated pursuant to Sections 8.1(g), then Parent shall pay to the Company<br \/>\nan amount equal to the sum of the Company&#8217;s Expenses up to an amount equal to<br \/>\n$15 million.<\/p>\n<p>     (d) Payment of Expenses. Payment of Expenses pursuant to Sections 8.2(b) or<br \/>\n8.2(c) shall be made not later than two Business Days after delivery to the<br \/>\nother party of notice<\/p>\n<p>                                       48<\/p>\n<p>of demand for payment and a documented itemization setting forth in reasonable<br \/>\ndetail all Expenses of the party entitled to receive payment (which itemization<br \/>\nmay be supplemented and updated from time to time by such party until the<br \/>\nninetieth day after such party delivers such notice of demand for payment).<\/p>\n<p>     (e) Company Termination Fee.<\/p>\n<p>         (i) In the event that this Agreement is terminated pursuant to (A)<br \/>\nSection 8.1(d)(i) and the Board of Directors of the Company has withdrawn or<br \/>\nadversely modified the Company Recommendation in such a manner that the Company<br \/>\ncannot submit this Agreement to a vote of the Company&#8217;s shareholders pursuant to<br \/>\nSection 23B.11.030(2) of the WBCA, (B) Section 8.1(d)(ii), or (C) Section<br \/>\n8.1(d)(iii), then the Company shall pay to Parent, within two Business Days<br \/>\nfollowing written notice of such termination, a termination fee of $475,000,000<br \/>\nin immediately available funds.<\/p>\n<p>         (ii) In the event that the Company shall have withdrawn or adversely<br \/>\nmodified the Company Recommendation prior to the Company Shareholders&#8217; Meeting<br \/>\nand this Agreement is terminated pursuant to Section 8.1(h)(i), then the Company<br \/>\nshall pay to Parent, within two Business Days following written notice of such<br \/>\ntermination, a termination fee of $475,000,000 in immediately available funds.<\/p>\n<p>         (iii) In the event that (A) this Agreement is terminated pursuant to<br \/>\nSection 8.1(h)(i) and, at any time after the date of this Agreement and before<br \/>\nthe vote on this Agreement at the Company Shareholders&#8217; Meeting, an Acquisition<br \/>\nProposal with respect to the Company shall have been publicly announced and not<br \/>\nbona fide withdrawn and (B) a Competing Transaction with respect to the Company<br \/>\nis consummated or the Company enters into a definitive agreement with respect to<br \/>\na Competing Transaction, in either case, within twelve months following the<br \/>\ntermination of this Agreement, then the Company shall pay to Parent, within two<br \/>\nBusiness Days after the earlier of the consummation of such Competing<br \/>\nTransaction or execution of a definitive agreement with respect to such<br \/>\nCompeting Transaction, a fee of $475,000,000 in immediately available funds.<\/p>\n<p>     (f) Parent Termination Fee.<\/p>\n<p>         (i) In the event that the Board of Directors of Parent shall have<br \/>\nwithdrawn or adversely modified the Parent Recommendation and, thereafter, this<br \/>\nAgreement is terminated pursuant to Section 8.1(h)(ii), then Parent shall pay to<br \/>\nthe Company, within two Business Days following written notice of such<br \/>\ntermination, a termination fee of $475,000,000 in immediately available funds.<\/p>\n<p>         (ii) In the event that this Agreement is terminated pursuant to Section<br \/>\n8.1(e)(ii), then Parent shall pay to the Company, within two Business Days<br \/>\nfollowing written notice of such termination, a termination fee of $475,000,000<br \/>\nin immediately available funds.<\/p>\n<p>     (g) All Payments. All payments under Section 8.2 shall be made by wire<br \/>\ntransfer of immediately available funds to an account designated by the party<br \/>\nentitled to receive payment. The Company and Parent acknowledge that the<br \/>\nagreements contained in Section 8.2<\/p>\n<p>                                       49<\/p>\n<p>are an integral part of the transactions contemplated by this Agreement and<br \/>\nthat, without these agreements, neither the Company nor Parent would enter into<br \/>\nthis Agreement. Accordingly, if either party fails promptly to pay any amount<br \/>\ndue pursuant to this Section 8.2 and, in order to obtain such payment, the<br \/>\nCompany or Parent, as applicable, commences a suit which results in a judgment<br \/>\nagainst the other party for the fee set forth in this Section 8.2, such<br \/>\ndefaulting party shall pay to the prevailing party its costs and expenses<br \/>\n(including reasonable attorneys&#8217; fees and expenses) in connection with such<br \/>\nsuit, together with interest on the amount of the fee at the prime rate of<br \/>\nCitibank, N.A. in effect on the date such payment was required to be made.<\/p>\n<p>     Section 8.3 Amendment. This Agreement may be amended by the parties hereto<br \/>\n                 &#8212;&#8212;&#8212;<br \/>\nby action taken by or on behalf of their respective Boards of Directors at any<br \/>\ntime prior to the Effective Time; provided, however, that, after approval of the<br \/>\nMerger by the shareholders of the Company, no amendment may be made without<br \/>\nfurther shareholder approval which, by Law or in accordance with the rules of<br \/>\nNasdaq, requires further approval by such shareholders. This Agreement may not<br \/>\nbe amended except by an instrument in writing signed by the parties hereto.<\/p>\n<p>     Section 8.4 Waiver. At any time prior to the Effective Time, any party<br \/>\n                 &#8212;&#8212;<br \/>\nhereto may (a) extend the time for the performance of any of the obligations or<br \/>\nother acts of the other party hereto, (b) waive any inaccuracies in the<br \/>\nrepresentations and warranties of the other party contained herein or in any<br \/>\ndocument delivered pursuant hereto, and (c) waive compliance by the other party<br \/>\nwith any of the agreements or conditions contained herein; provided, however,<br \/>\nthat after any approval of the transactions contemplated by this Agreement by<br \/>\nthe shareholders of the Company, there may not be, without further approval of<br \/>\nsuch shareholders, any extension or waiver of this Agreement or any portion<br \/>\nthereof which, by Law or in accordance with the rules of Nasdaq, requires<br \/>\nfurther approval by such shareholders. Any such extension or waiver shall be<br \/>\nvalid only if set forth in an instrument in writing signed by the party or<br \/>\nparties to be bound thereby, but such extension or waiver or failure to insist<br \/>\non strict compliance with an obligation, covenant, agreement or condition shall<br \/>\nnot operate as a waiver of, or estoppel with respect to, any subsequent or other<br \/>\nfailure.<\/p>\n<p>     Section 8.5 Fees and Expenses. Subject to Sections 8.2(a), 8.2(b), 8.2(c)<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nand 8.2(g), all expenses incurred by the parties hereto shall be borne solely<br \/>\nand entirely by the party which has incurred the same; provided, however, that<br \/>\neach of Parent and the Company shall pay one-half of the expenses related to<br \/>\nprinting, filing and mailing the Registration Statement and the Proxy Statement<br \/>\nand all SEC and other regulatory filing fees incurred in connection with the<br \/>\nRegistration Statement and the Proxy Statement.<\/p>\n<p>                                   ARTICLE 9.<br \/>\n                               GENERAL PROVISIONS<\/p>\n<p>     Section 9.1 Non-Survival of Representations and Warranties. None of the<br \/>\n                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nrepresentations and warranties in this Agreement or in any instrument delivered<br \/>\npursuant to this Agreement shall survive the Effective Time. This Section 9.1<br \/>\nshall not limit any covenant or agreement of the parties which by its terms<br \/>\ncontemplates performance after the Effective Time.<\/p>\n<p>     Section 9.2 Notices. Any notices or other communications required or<br \/>\n                 &#8212;&#8212;-<br \/>\npermitted under, or otherwise in connection with this Agreement shall be in<br \/>\nwriting and shall be<\/p>\n<p>                                       50<\/p>\n<p>deemed to have been duly given when delivered in person or upon confirmation of<br \/>\nreceipt when transmitted by facsimile transmission (but only if followed by<br \/>\ntransmittal by national overnight courier or hand for delivery on the next<br \/>\nBusiness Day) or on receipt after dispatch by registered or certified mail,<br \/>\npostage prepaid, addressed, or on the next Business Day if transmitted by<br \/>\nnational overnight courier, in each case as follows:<\/p>\n<p>                (a)        If to Parent or Merger Sub, addressed to it at:<\/p>\n<p>                           Amgen Inc.<br \/>\n                           One Amgen Center Drive<br \/>\n                           Thousand Oaks, CA  91320<br \/>\n                           Fax:  (805) 499-3540<br \/>\n                           Attn:  Chief Executive Officer<\/p>\n<p>                           with a copy to:<\/p>\n<p>                           Latham &amp; Watkins<br \/>\n                           885 Third Avenue, Suite 1000<br \/>\n                           New York, NY  10022-4802<br \/>\n                           Fax:  (212) 751-4864<br \/>\n                           Attn:  Charles Nathan<\/p>\n<p>                           and<\/p>\n<p>                           Latham &amp; Watkins<br \/>\n                           633 West Fifth Street, Suite 4000<br \/>\n                           Los Angeles, CA  90071-2007<br \/>\n                           Fax:  (213) 891-8763<br \/>\n                           Attn:   Gary Olson<br \/>\n                                   Paul D. Tosetti<br \/>\n                                   Charles K. Ruck<\/p>\n<p>                (b)        If to the Company, addressed to it at:<\/p>\n<p>                           Immunex Corporation<br \/>\n                           51 University Street<br \/>\n                           Seattle, Washington  98101<br \/>\n                           Fax:  (206) 467-0368<br \/>\n                           Attn:  Chief Executive Officer<\/p>\n<p>                           with a copy to:<\/p>\n<p>                           Skadden, Arps, Slate, Meagher &amp; Flom LLP<br \/>\n                           Four Times Square<br \/>\n                           New York, NY  10036<br \/>\n                           Fax:  (212) 735-2000<br \/>\n                           Attn:   Roger Aaron<\/p>\n<p>                                       51<\/p>\n<p>                                   Stephen Arcano<\/p>\n<p>     Section 9.3   Certain Definitions. For purposes of this Agreement,<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nthe term:<\/p>\n<p>     &#8220;Accelerated Company Option&#8221; shall mean a Company Option with<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\na per share exercise price which is equal to or less than the greater of (i)<br \/>\n$40.00 or (ii) the closing sales price for a share of Company Common Stock (or<br \/>\nthe closing bid, if no sales were reported) as quoted on Nasdaq for the last<br \/>\nmarket trading day immediately preceding the Effective Time, as reported in The<br \/>\nWall Street Journal.<\/p>\n<p>     &#8220;Acquisition Proposal&#8221; means any offer or proposal concerning any (a)<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nmerger, consolidation, business combination, or similar transaction involving<br \/>\nthe Company or any Significant Subsidiary of the Company pursuant to which the<br \/>\nshareholders of the Company immediately prior to such transaction would own less<br \/>\nthan 80% of any class of equity securities of the entity surviving or resulting<br \/>\nfrom such transaction (or the ultimate parent entity thereof), (b) sale or other<br \/>\ndisposition directly or indirectly of assets of the Company or the Company<br \/>\nSubsidiaries representing 20% or more of the consolidated assets of the Company<br \/>\nand the Company Subsidiaries, (c) issuance, sale, or other disposition of<br \/>\nsecurities (or options, rights or warrants to purchase, or securities<br \/>\nconvertible into or exchangeable for, such securities) in each case by the<br \/>\nCompany representing 20% or more of the voting power of the Company or (d)<br \/>\ntransaction in which any person shall acquire beneficial ownership, or the right<br \/>\nto acquire beneficial ownership or any group shall have been formed which<br \/>\nbeneficially owns or has the right to acquire beneficial ownership of, 20% or<br \/>\nmore of the outstanding voting capital stock of the Company (other than the<br \/>\nMerger).<\/p>\n<p>     &#8220;Affiliate&#8221; of a specified person means a person that directly or<br \/>\n      &#8212;&#8212;&#8212;<br \/>\nindirectly, through one or more intermediaries, controls, is controlled by, or<br \/>\nis under common control with, the person specified.<\/p>\n<p>     &#8220;beneficial ownership&#8221; (and related terms such as &#8220;beneficially owned&#8221; or<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\n&#8220;beneficial owner&#8221;) has the meaning set forth in Rule 13d-3 under the Exchange<br \/>\nAct.<\/p>\n<p>     &#8220;Blue Sky Laws&#8221; means state securities or &#8220;blue sky&#8221; Laws.<br \/>\n      &#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>     &#8220;Business Day&#8221; means any day on which banks are not required or authorized<br \/>\n      &#8212;&#8212;&#8212;&#8212;<br \/>\nto close in the City of New York.<\/p>\n<p>     &#8220;Cancelled Company Option&#8221; shall mean a Company Option with a per share<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nexercise price which exceeds the greater of (i) $40.00 or (ii) the closing sales<br \/>\nprice for a share of Company Common Stock (or the closing bid, if no sales were<br \/>\nreported) as quoted on Nasdaq for the last market trading day immediately<br \/>\npreceding the Effective Time, as reported in The Wall Street Journal.<\/p>\n<p>     &#8220;CERCLA&#8221; means the Comprehensive Environmental Response, Compensation and<br \/>\n      &#8212;&#8212;<br \/>\nLiability Act of 1980, as amended as of the date hereof.<\/p>\n<p>     &#8220;Company Intellectual Property&#8221; means all intellectual property or other<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nproprietary rights of every kind, foreign or domestic, including all patents,<br \/>\npatent applications,<\/p>\n<p>                                       52<\/p>\n<p>inventions (whether or not patentable), processes, products, technologies,<br \/>\ndiscoveries, copyrightable and copyrighted works, apparatus, trade secrets,<br \/>\ntrademarks, trademark registrations and applications, domain names, service<br \/>\nmarks, service mark registrations and applications, trade names, trade secrets,<br \/>\nknow-how, trade dress, copyright registrations, customer lists, confidential<br \/>\nmarketing and customer information, licenses, confidential technical<br \/>\ninformation, software, and all documentation thereof, in each case, used in the<br \/>\nbusiness of the Company as of the date of this Agreement or the Closing Date.<\/p>\n<p>     &#8220;Company Material Adverse Effect&#8221; means any change affecting, or condition<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nhaving an effect on, the Company or any Company Subsidiary that is, or would<br \/>\nreasonably be expected to be, materially adverse to the business, financial<br \/>\ncondition or results of operations of the Company and the Company Subsidiaries,<br \/>\ntaken as a whole, except, in each case, for any such change or condition<br \/>\nresulting from or arising out of (i) changes or developments in the<br \/>\nbiotechnology industry generally, which changes or developments do not<br \/>\ndisproportionately affect the Company relative to other participants in the<br \/>\nbiotechnology industry in any material respect, (ii) changes or developments in<br \/>\nfinancial or securities markets or the economy in general which changes do not<br \/>\ndisproportionately affect the Company in any material respect, (iii) any change<br \/>\nin the Company&#8217;s stock price or trading volume, in and of itself or (iv) the<br \/>\nannouncement of the transactions contemplated by this Agreement.<\/p>\n<p>     &#8220;Company Option&#8221; means any option or warrant to purchase Company Common<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nStock.<\/p>\n<p>     &#8220;Company Stock Option Plan&#8221; means the Immunex Corporation 1993 Stock Option<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nPlan, as Amended and Restated on April 25, 2000, the Immunex Corporation 1999<br \/>\nStock Option Plan, as Amended and Restated on April 25, 2000, the Stock Option<br \/>\nGrant Program for Nonemployee Directors under the Immunex Corporation Amended<br \/>\nand Restated 1999 Stock Option Plan, the Immunex Corporation Stock Option Plan<br \/>\nfor Nonemployee Directors, as Amended and Restated on April 18, 2000, and in<br \/>\neach case, the addendums thereto, or any other plan, agreement or arrangement<br \/>\npursuant to which Company Options have been issued as of the Effective Time,<br \/>\nother than the ESPP.<\/p>\n<p>     &#8220;Competing Transaction&#8221; means any (a) merger, consolidation, business<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\ncombination, or similar transaction involving the Company or any Significant<br \/>\nSubsidiary of the Company pursuant to which the shareholders of the Company<br \/>\nimmediately prior to such transaction would own less than 70% of any class of<br \/>\nequity securities of the entity surviving or resulting from such transaction (or<br \/>\nthe ultimate parent entity thereof), (b) sale or other disposition directly or<br \/>\nindirectly of assets of the Company or the Company Subsidiaries representing 30%<br \/>\nor more of the consolidated assets of the Company and the Company Subsidiaries,<br \/>\n(c) issuance, sale, or other disposition of securities (or options, rights or<br \/>\nwarrants to purchase, or securities convertible into or exchangeable for, such<br \/>\nsecurities) in each case by the Company to any person or &#8220;group&#8221; (as defined in<br \/>\nRule 13d-5(b)(1) under the Exchange Act) representing 30% or more of the voting<br \/>\npower of the Company or (d) transaction in which any person shall acquire<br \/>\nbeneficial ownership, or the right to acquire beneficial ownership or any group<br \/>\nshall have been formed which beneficially owns or has the right to acquire<br \/>\nbeneficial ownership of, 30% or more of the outstanding voting capital stock of<br \/>\nthe Company (other than any shares beneficially owned by AHP or its<br \/>\nSubsidiaries).<\/p>\n<p>                                       53<\/p>\n<p>     &#8220;Contracts&#8221; means any of the agreements, contracts, leases, powers of<br \/>\n      &#8212;&#8212;&#8212;<br \/>\nattorney, notes, loans, evidence of indebtedness, purchase orders, letters of<br \/>\ncredit, settlement agreements, franchise agreements, undertakings, covenants not<br \/>\nto compete, employment agreements, licenses, instruments, obligations,<br \/>\ncommitments, understandings, policies, purchase and sales orders, quotations and<br \/>\nother executory commitments to which any company is a party or to which any of<br \/>\nthe assets of the companies are subject, whether oral or written, express or<br \/>\nimplied.<\/p>\n<p>     &#8220;control&#8221; (including the terms &#8220;controlled by&#8221; and &#8220;under common control<br \/>\n      &#8212;&#8212;-<br \/>\nwith&#8221;) means the possession, directly or indirectly or as trustee or executor,<br \/>\nof the power to direct or cause the direction of the management or policies of a<br \/>\nperson, whether through the ownership of securities or as trustee or executor,<br \/>\nby Contract or credit arrangement or otherwise.<\/p>\n<p>     &#8220;delivered&#8221; or &#8220;made available&#8221; (or words of similar import) shall include,<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nwithout limitation, all documents and materials made available in the Company&#8217;s<br \/>\ndata rooms in Los Angeles, California or New York, New York or Parent&#8217;s data<br \/>\nrooms in Los Angeles, California or New York, New York, as the case may be.<\/p>\n<p>     &#8220;Environmental Laws&#8221; means any federal, state, local or<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nforeign statute, Law, ordinance, regulation, rule, code, treaty, writ or order<br \/>\nand any enforceable judicial or administrative interpretation thereof, including<br \/>\nany judicial or administrative order, consent decree, judgment, stipulation,<br \/>\ninjunction, permit, authorization, policy, opinion, or agency requirement, in<br \/>\neach case having the force and effect of Law, relating to the pollution,<br \/>\nprotection, investigation or restoration of the environment, health and safety<br \/>\nas affected by the environment or natural resources, including, without<br \/>\nlimitation, those relating to the use, handling, presence, transportation,<br \/>\ntreatment, storage, disposal, release, threatened release or discharge of<br \/>\nHazardous Materials or noise, odor, wetlands, pollution or contamination.<\/p>\n<p>     &#8220;Environmental Permits&#8221; means any permit, approval, identification number,<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nlicense and other authorization required under any applicable Environmental Law.<\/p>\n<p>     &#8220;Equity Interest&#8221; means any share, capital stock, partnership, member or<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nsimilar interest in any entity, and any option, warrant, right or security<br \/>\n(including debt securities) convertible, exchangeable or exercisable therefor.<\/p>\n<p>     &#8220;ERISA&#8221; means the Employee Retirement Income Security Act of 1974, as<br \/>\n      &#8212;&#8211;<br \/>\namended, and the regulations promulgated thereunder.<\/p>\n<p>     &#8220;ERISA Affiliate&#8221; means any entity or trade or business (whether or not<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nincorporated) other than the Company that together with the Company is<br \/>\nconsidered under common control and treated as a single employer under Section<br \/>\n4.14(b), (c), (m) or (o) of the Code.<\/p>\n<p>     &#8220;Exchange Act&#8221; means the Securities Exchange Act of 1934, as amended, and<br \/>\n      &#8212;&#8212;&#8212;&#8212;<br \/>\nthe rules and regulations promulgated thereunder.<\/p>\n<p>     &#8220;Expenses&#8221; includes all reasonable out-of-pocket expenses (including,<br \/>\n      &#8212;&#8212;&#8211;<br \/>\nwithout limitation, all reasonable fees and expenses of counsel, accountants,<br \/>\ninvestment bankers, experts and consultants to a party hereto and its<br \/>\nAffiliates) incurred by a party or on its behalf in<\/p>\n<p>                                       54<\/p>\n<p>connection with or related to the authorization, preparation, negotiation,<br \/>\nexecution and performance of this Agreement and the transactions contemplated<br \/>\nhereby, including the preparation, printing, filing and mailing of the<br \/>\nRegistration Statement and Proxy Statement, as applicable, and the solicitation<br \/>\nof shareholder approvals and all other matters related to the transactions<br \/>\ncontemplated hereto.<\/p>\n<p>     &#8220;GAAP&#8221; means generally accepted accounting principles as applied in the<br \/>\n      &#8212;-<br \/>\nUnited States.<\/p>\n<p>     &#8220;Governance Agreement&#8221; means that certain Amended and Restated Governance<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nAgreement dated as of December 15, 1992 among American Cyanamid Company, Lederle<br \/>\nOncology Corporation and the Company, as amended by Amendment No. 1 to the<br \/>\nAmended and Restated Governance Agreement dated May 20, 1999 between American<br \/>\nCyanamid Company and the Company and Amendment No. 2 to Amended and Restated<br \/>\nGovernance Agreement dated August 9, 2000 between American Cyanamid Company and<br \/>\nthe Company.<\/p>\n<p>     &#8220;Governmental Entity&#8221; means domestic or foreign governmental,<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nadministrative, judicial or regulatory authority.<\/p>\n<p>     &#8220;group&#8221; is defined as in the Exchange Act, except where the context<br \/>\n      &#8212;&#8211;<br \/>\notherwise requires.<\/p>\n<p>     &#8220;Hazardous Materials&#8221; means (A) any petroleum, petroleum products,<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nbyproducts or breakdown products, radioactive materials, asbestos-containing<br \/>\nmaterials or polychlorinated biphenyls or (B) any chemical, material or other<br \/>\nsubstance defined or regulated as toxic or hazardous or as a pollutant or<br \/>\ncontaminant or waste under any applicable Environmental Law.<\/p>\n<p>     &#8220;HSR Act&#8221; means the Hart-Scott-Rodino Antitrust Improvements Act of 1976,<br \/>\n      &#8212;&#8212;-<br \/>\nas amended, and the rules and regulations thereunder.<\/p>\n<p>     &#8220;Intellectual Property&#8221; means intellectual property or other proprietary<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nrights of every kind, foreign or domestic, including all patents, patent<br \/>\napplications, inventions (whether or not patentable), processes, products,<br \/>\ntechnologies, discoveries, copyrightable and copyrighted works, apparatus, trade<br \/>\nsecrets, trademarks, trademark registrations and applications, domain names,<br \/>\nservice marks, service mark registrations and applications, trade names, trade<br \/>\nsecrets, know-how, trade dress, copyright registrations, customer lists,<br \/>\nconfidential marketing and customer information, licenses, confidential<br \/>\ntechnical information, software, and all documentation thereof.<\/p>\n<p>     &#8220;Knowledge&#8221; of any person which is not an individual means, with respect to<br \/>\n      &#8212;&#8212;&#8212;<br \/>\nany specific matter, the actual knowledge of such person&#8217;s executive officers<br \/>\nand any other officer having primary responsibility for such matter.<\/p>\n<p>     &#8220;Law&#8221; means foreign or domestic law, statute, code, ordinance, rule,<br \/>\n      &#8212;<br \/>\nregulation, order, judgment, writ, stipulation, award, injunction, decree or<br \/>\narbitration award or finding.<\/p>\n<p>     &#8220;Liens&#8221; means any mortgage, pledge, lien, security interest, conditional or<br \/>\n      &#8212;&#8211;<br \/>\ninstallment sale agreement, encumbrance, charge or other claims of third parties<br \/>\nof any kind.<\/p>\n<p>                                       55<\/p>\n<p>     &#8220;Nasdaq&#8221; means the Nasdaq Stock Market.<br \/>\n      &#8212;&#8212;<\/p>\n<p>     &#8220;Parent Certificate&#8221; means Parent&#8217;s Restated Certificate of Incorporation,<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nas amended through the date of this Agreement.<\/p>\n<p>     &#8220;Parent Intellectual Property&#8221; means all intellectual property or other<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nproprietary rights of every kind, foreign or domestic, including all patents,<br \/>\npatent applications, inventions (whether or not patentable), processes,<br \/>\nproducts, technologies, discoveries, copyrightable and copyrighted works,<br \/>\napparatus, trade secrets, trademarks, trademark registrations and applications,<br \/>\ndomain names, service marks, service mark registrations and applications, trade<br \/>\nnames, trade secrets, know-how, trade dress, copyright registrations, customer<br \/>\nlists, confidential marketing and customer information, licenses, confidential<br \/>\ntechnical information, software, and all documentation thereof, in each case,<br \/>\nused in the business of Parent as of the date of this Agreement or the Closing<br \/>\nDate.<\/p>\n<p>     &#8220;Parent Material Adverse Effect&#8221; means any change affecting,<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nor condition having an effect on, Parent, Merger Sub or any of Parent&#8217;s<br \/>\nSubsidiaries that is, or would reasonably be expected to be, materially adverse<br \/>\nto the business, financial condition or results of operations of Parent and its<br \/>\nSubsidiaries, taken as a whole, except, in each case, for any such change or<br \/>\ncondition resulting from or arising out of (i) changes or developments in the<br \/>\nbiotechnology industry generally, which changes or developments do not<br \/>\ndisproportionately affect Parent relative to other participants in the<br \/>\nbiotechnology industry in any material respect, (ii) changes or developments in<br \/>\nfinancial or securities markets or the economy in general which changes do not<br \/>\ndisproportionately affect Parent in any material respect, (iii) any change in<br \/>\nParent&#8217;s stock price or trading volume, in and of itself or (iv) the<br \/>\nannouncement of the transactions contemplated by this Agreement.<\/p>\n<p>     &#8220;PBGC&#8221; means the Pension Benefit Guaranty Corporation.<br \/>\n      &#8212;-<\/p>\n<p>     &#8220;Permitted Liens&#8221; means (a) Liens for Taxes, assessments or similar charges<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\nincurred in the ordinary course of business consistent with past practice that<br \/>\nare not yet due and payable or are being contested in good faith; (b) pledges or<br \/>\ndeposits made in the ordinary course of business consistent with past practice;<br \/>\n(c) Liens of mechanics, materialmen, warehousemen or other like Liens securing<br \/>\nobligations incurred in the ordinary course of business consistent with past<br \/>\npractice that are not yet due and payable or are being contested in good faith;<br \/>\nand (iv) similar Liens and encumbrances which are incurred in the ordinary<br \/>\ncourse of business consistent with past practice and which do not in the<br \/>\naggregate materially detract from the value of such assets or properties or<br \/>\nmaterially impair the use thereof in the operation of such business.<\/p>\n<p>     &#8220;person&#8221; means an individual, corporation, limited liability company,<br \/>\n      &#8212;&#8212;<br \/>\npartnership, association, trust, unincorporated organization, other entity or<br \/>\ngroup.<\/p>\n<p>     &#8220;SEC&#8221; means the United States Securities and Exchange Commission.<br \/>\n      &#8212;<\/p>\n<p>     &#8220;Securities Act&#8221; means the Securities Act of 1933, as amended, and the<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nrules and regulations promulgated thereunder.<\/p>\n<p>                                       56<\/p>\n<p>     &#8220;Share Issuance&#8221; means the issuance of Parent Common Stock pursuant to<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nSection 2.1(a).<\/p>\n<p>     &#8220;Significant Subsidiary&#8221; has the meaning set forth in Rule 1-02 of<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nRegulation S-X.<\/p>\n<p>     &#8220;Subsidiary&#8221; or &#8220;Subsidiaries&#8221; of any person or any other person means any<br \/>\n      &#8212;&#8212;&#8212;-      &#8212;&#8212;&#8212;&#8212;<br \/>\ncorporation, partnership, joint venture or other legal entity of which such<br \/>\nperson, as the case may be (either alone or through or together with any other<br \/>\nsubsidiary), owns, directly or indirectly, a majority of the stock or other<br \/>\nequity interests the holders of which are generally entitled to vote for the<br \/>\nelection of the Board of Directors or other governing body of such corporation<br \/>\nor other legal entity.<\/p>\n<p>     &#8220;Superior Proposal&#8221; means any bona fide offer or proposal (on its most<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nrecently amended or modified terms, if amended or modified) made by a person<br \/>\nother than Parent or Merger Sub that (1) concerns any (a) merger, tender offer,<br \/>\nexchange offer, business combination or similar transaction involving the<br \/>\nCompany or any Subsidiary of the Company pursuant to which (i) shareholders of<br \/>\nthe Company immediately prior to such transaction would own less than 50% of the<br \/>\nvoting power of the entity surviving or resulting from such transaction (or the<br \/>\nultimate parent entity thereof) and (ii) shareholders of the Company other than<br \/>\nAHP would own less than 30% of the voting power of the entity surviving or<br \/>\nresulting from such transaction (or the ultimate parent entity thereof) or (b)<br \/>\nsale or other disposition directly or indirectly of assets of the Company or the<br \/>\nCompany Subsidiaries representing 67% or more of the consolidated assets of the<br \/>\nCompany and the Company Subsidiaries, (2) is on terms which the Board of<br \/>\nDirectors of the Company in good faith concludes (following receipt of the<br \/>\nadvice of its financial advisors and outside counsel) are more favorable to the<br \/>\nCompany&#8217;s shareholders (in their capacities as shareholders) than the<br \/>\ntransactions contemplated by this Agreement (including any revisions hereto),<br \/>\nand (3) is, in the good faith judgment of the Company, reasonably likely to be<br \/>\ncompleted and financed.<\/p>\n<p>     &#8220;Taxes&#8221; means all taxes of any kind, including, without limitation, those<br \/>\n      &#8212;&#8211;<br \/>\non or measured by or referred to as income, gross receipts, sales, use, ad<br \/>\nvalorem, franchise, profits, license, withholding, payroll, employment, excise,<br \/>\nseverance, stamp, occupation, premium, value added, property or windfall profits<br \/>\ntaxes, customs, duties or similar fees, assessments or charges of any kind<br \/>\nwhatsoever, together with any interest and any penalties, additions to tax or<br \/>\nadditional amounts imposed by any Governmental Entity.<\/p>\n<p>     &#8220;Tax Returns&#8221; means any report, return (including information return),<br \/>\n      &#8212;&#8212;&#8212;&#8211;<br \/>\nclaim for refund, or statement relating to Taxes, including any schedule or<br \/>\nattachment thereto, and including any amendments thereof.<\/p>\n<p>     &#8220;Treasury Regulations&#8221; means the United States Treasury regulations<br \/>\n      &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\npromulgated under the Code.<\/p>\n<p>                                       57<\/p>\n<p>     Section 9.4  Terms Defined Elsewhere. The following terms are defined<br \/>\n                  &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nelsewhere in this Agreement, as indicated below:<\/p>\n<p>     &#8220;Agreement&#8221;                                         Preamble<\/p>\n<p>     &#8220;AHP&#8221;                                               Recitals<\/p>\n<p>     &#8220;AHP Agreements&#8221;                                 Section 2.7<\/p>\n<p>     &#8220;Articles of Merger&#8221;                             Section 1.2<\/p>\n<p>     &#8220;Cash Consideration&#8221;                          Section 2.1(a)<\/p>\n<p>     &#8220;Certificates&#8221;                                Section 2.2(b)<\/p>\n<p>     &#8220;Change of Recommendation&#8221;                    Section 6.4(e)<\/p>\n<p>     &#8220;Closing&#8221;                                        Section 1.2<\/p>\n<p>     &#8220;Closing Date&#8221;                                   Section 1.2<\/p>\n<p>     &#8220;Code&#8221;                                              Recitals<\/p>\n<p>     &#8220;Common Stock Consideration&#8221;                  Section 2.1(a)<\/p>\n<p>     &#8220;Company&#8221;                                           Preamble<\/p>\n<p>     &#8220;Company Articles&#8221;                               Section 3.2<\/p>\n<p>     &#8220;Company Benefit Plan&#8221;                        Section 3.9(a)<\/p>\n<p>     &#8220;Company Bylaws&#8221;                                 Section 3.2<\/p>\n<p>     &#8220;Company Common Stock&#8221;                        Section 2.1(a)<\/p>\n<p>     &#8220;Company Disclosure Letter&#8221;                        Article 3<\/p>\n<p>     &#8220;Company Financial Advisor&#8221;                     Section 3.20<\/p>\n<p>     &#8220;Company Form 10-K&#8221;                           Section 3.7(c)<\/p>\n<p>     &#8220;Company Material Contract&#8221;                     Section 3.12<\/p>\n<p>     &#8220;Company Pharmaceutical Products&#8221;            Section 3.19(a)<\/p>\n<p>     &#8220;Company Permits&#8221;                                Section 3.6<\/p>\n<p>     &#8220;Company Preferred Stock&#8221;                     Section 3.3(a)<\/p>\n<p>                                       58<\/p>\n<p>     &#8220;Company Recommendation&#8221;                                  Section 6.2(c)<\/p>\n<p>     &#8220;Company SEC Filings&#8221;                                     Section 3.7(a)<\/p>\n<p>     &#8220;Company Shareholder Approval&#8221;                              Section 3.21<\/p>\n<p>     &#8220;Company Shareholders&#8217; Meeting&#8221;                           Section 6.2(a)<\/p>\n<p>     &#8220;Company Subsidiaries&#8221;                                       Section 3.1<\/p>\n<p>     &#8220;Confidentiality Agreement&#8221;                               Section 6.3(b)<\/p>\n<p>     &#8220;D&amp;O Insurance&#8221;                                          Section 6.10(b)<\/p>\n<p>     &#8220;Director Plans&#8221;                                             Section 2.4<\/p>\n<p>     &#8220;Dissenting Share&#8221;                                        Section 2.1(e)<\/p>\n<p>     &#8220;Effective Time&#8221;                                             Section 1.2<\/p>\n<p>     &#8220;employee benefit plan&#8221;                                   Section 3.9(a)<\/p>\n<p>     &#8220;ESPP&#8221;                                                       Section 2.5<\/p>\n<p>     &#8220;Excess Shares&#8221;                                        Section 2.2(e)(i)<\/p>\n<p>     &#8220;Exchange Agent&#8221;                                          Section 2.2(a)<\/p>\n<p>     &#8220;Exchange Fund&#8221;                                           Section 2.2(a)<\/p>\n<p>     &#8220;Exchange Ratio&#8221;                                          Section 2.1(a)<\/p>\n<p>     &#8220;FDA&#8221;                                                        Section 3.6<\/p>\n<p>     &#8220;FDCA&#8221;                                                       Section 3.6<\/p>\n<p>     &#8220;Forward Subsidiary Merger&#8221;                                 Section 6.15<\/p>\n<p>     &#8220;IRS&#8221;                                                     Section 3.9(a)<\/p>\n<p>     &#8220;Joint Proxy\/Prospectus&#8221;                                  Section 6.1(a)<\/p>\n<p>     &#8220;Litigation Conditions&#8221;                                   Section 8.1(b)<\/p>\n<p>     &#8220;Merger&#8221;                                                        Recitals<\/p>\n<p>     &#8220;Merger Consideration&#8221;                                    Section 2.1(a)<\/p>\n<p>     &#8220;Merger Sub&#8221;                                                    Preamble<\/p>\n<p>                                       59<\/p>\n<p>      &#8220;multiemployer plan&#8221;                                      Section 3.9(d)<\/p>\n<p>      &#8220;New Parent Employees&#8221;                                    Section 6.9(a)<\/p>\n<p>      &#8220;Option Exchange Ratio&#8221;                                   Section 2.4(a)<\/p>\n<p>      &#8220;Outside Date&#8221;                                            Section 8.1(b)<\/p>\n<p>      &#8220;Parent&#8221;                                                        Preamble<\/p>\n<p>      &#8220;Parent Benefit Plans&#8221;                                    Section 6.9(b)<\/p>\n<p>      &#8220;Parent Bylaws&#8221;                                              Section 4.2<\/p>\n<p>      &#8220;Parent Common Stock&#8221;                                     Section 2.1(a)<\/p>\n<p>      &#8220;Parent Disclosure Letter&#8221;                                    Article 4.<\/p>\n<p>      &#8220;Parent Financial Advisor&#8221;                                  Section 4.14<\/p>\n<p>      &#8220;Parent Form 10-K&#8221;                                        Section 4.7(c)<\/p>\n<p>      &#8220;Parent Permits&#8221;                                             Section 4.6<\/p>\n<p>      &#8220;Parent Pharmaceutical Products&#8221;                         Section 4.12(a)<\/p>\n<p>      &#8220;Parent Preferred Stock&#8221;                                  Section 4.3(a)<\/p>\n<p>      &#8220;Parent Recommendation&#8221;                                   Section 6.2(d)<\/p>\n<p>      &#8220;Parent SEC Filings&#8221;                                      Section 4.7(a)<\/p>\n<p>      &#8220;Parent Stockholder Approval&#8221;                               Section 4.15<\/p>\n<p>      &#8220;Parent Stockholders&#8217; Meeting&#8221;                            Section 6.2(b)<\/p>\n<p>      &#8220;Parent Subsidiaries&#8221;                                        Section 4.1<\/p>\n<p>      &#8220;Product Rights Agreement&#8221;                                  Section 3.15<\/p>\n<p>      &#8220;Registration Statement&#8221;                                  Section 6.1(a)<\/p>\n<p>      &#8220;Proxy Statement&#8221;                                         Section 6.1(a)<\/p>\n<p>      &#8220;Replacement Option&#8221;                                      Section 2.4(b)<\/p>\n<p>      &#8220;Representatives&#8221;                                         Section 6.3(a)<\/p>\n<p>      &#8220;Rights Plan&#8221;                                             Section 2.1(f)<\/p>\n<p>                                       60<\/p>\n<p>     &#8220;Section 16&#8221;                                                Section 6.13<\/p>\n<p>     &#8220;Superior Proposal Notice&#8221;                                Section 6.4(c)<\/p>\n<p>     &#8220;Surviving Corporation&#8221;                                      Section 1.1<\/p>\n<p>     &#8220;Voting Agreement&#8221;                                              Recitals<\/p>\n<p>     &#8220;WBCA&#8221;                                                          Recitals<\/p>\n<p>     Section 9.5   Headings. The headings contained in this Agreement are for<br \/>\n                   &#8212;&#8212;&#8211;<br \/>\nreference purposes only and shall not affect in any way the meaning or<br \/>\ninterpretation of this Agreement.<\/p>\n<p>     Section 9.6   Severability. If any term or other provision of this<br \/>\n                   &#8212;&#8212;&#8212;&#8212;<br \/>\nAgreement is invalid, illegal or incapable of being enforced by any rule of Law<br \/>\nor public policy, all other conditions and provisions of this Agreement shall<br \/>\nnevertheless remain in full force and effect so long as the economic or legal<br \/>\nsubstance of the transactions contemplated hereby is not affected in any manner<br \/>\nmaterially adverse to any party. Upon such determination that any term or other<br \/>\nprovision is invalid, illegal or incapable of being enforced, the parties hereto<br \/>\nshall negotiate in good faith to modify this Agreement so as to effect the<br \/>\noriginal intent of the parties as closely as possible in an acceptable manner to<br \/>\nthe end that transactions contemplated hereby are fulfilled to the extent<br \/>\npossible.<\/p>\n<p>     Section 9.7   Entire Agreement. This Agreement (together with the Exhibits,<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nParent and Company Disclosure Letters and the other documents delivered pursuant<br \/>\nhereto) and the Confidentiality Agreement constitute the entire agreement of the<br \/>\nparties and supersede all prior agreements and undertakings, both written and<br \/>\noral, between the parties, or any of them, with respect to the subject matter<br \/>\nhereof.<\/p>\n<p>     Section 9.8   Assignment. Neither this Agreement nor any of the rights,<br \/>\n                   &#8212;&#8212;&#8212;-<br \/>\ninterests or obligations hereunder shall be assigned by any of the parties<br \/>\nhereto, in whole or in part (whether by operation of Law or otherwise), without<br \/>\nthe prior written consent of the other parties, and any attempt to make any such<br \/>\nassignment without such consent shall be null and void, except that Merger Sub<br \/>\nmay assign, in its sole discretion, any or all of its rights, interests and<br \/>\nobligations under this Agreement to any direct wholly-owned Subsidiary of Parent<br \/>\nwithout the consent of the Company.<\/p>\n<p>     Section 9.9   Parties in Interest. This Agreement shall be binding upon and<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\ninure solely to the benefit of each party hereto and their respective successors<br \/>\nand assigns, and nothing in this Agreement, express or implied, other than<br \/>\npursuant to Section 6.11, is intended to or shall confer upon any other person<br \/>\nany right, benefit or remedy of any nature whatsoever under or by reason of this<br \/>\nAgreement.<\/p>\n<p>     Section 9.10   Mutual Drafting. Each party hereto has participated in the<br \/>\n                    &#8212;&#8212;&#8212;&#8212;&#8212;<br \/>\ndrafting of this Agreement, which each party acknowledges is the result of<br \/>\nextensive negotiations between the parties.<\/p>\n<p>                                       61<\/p>\n<p>     Section 9.11  Governing Law; Consent to Jurisdiction; Waiver of Trial by<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\nJury.<br \/>\n&#8212;-<\/p>\n<p>     (a) This Agreement and the transactions contemplated hereby, and all<br \/>\ndisputes between the parties under or related to the Agreement or the facts and<br \/>\ncircumstances leading to its execution, whether in Contract, tort or otherwise,<br \/>\nshall be governed by and construed in accordance with the Laws of the State of<br \/>\nDelaware, applicable to contracts executed in and to be performed entirely<br \/>\nwithin the State, except that the provisions of the WBCA shall govern the<br \/>\nMerger.<\/p>\n<p>     (b) Each of the parties hereto hereby irrevocably and unconditionally<br \/>\nsubmits, for itself and its property, to the exclusive jurisdiction of any<br \/>\nDelaware State court, or Federal court of the United States of America, sitting<br \/>\nin Delaware, and any appellate court from any thereof, in any action or<br \/>\nproceeding arising out of or relating to this Agreement or the agreements<br \/>\ndelivered in connection herewith or the transactions contemplated hereby or<br \/>\nthereby or for recognition or enforcement of any judgment relating thereto, and<br \/>\neach of the parties hereby irrevocably and unconditionally (a) agrees not to<br \/>\ncommence any such action or proceeding except in such courts, (b) agrees that<br \/>\nany claim in respect of any such action or proceeding may be heard and<br \/>\ndetermined in such Delaware State court or, to the extent permitted by Law, in<br \/>\nsuch Federal court, (c) waives, to the fullest extent it may legally and<br \/>\neffectively do so, any objection which it may now or hereafter have to the<br \/>\nlaying of venue of any such action or proceeding in any such Delaware State or<br \/>\nFederal court, and (d) waives, to the fullest extent permitted by Law, the<br \/>\ndefense of an inconvenient forum to the maintenance of such action or proceeding<br \/>\nin any such Delaware State or Federal court. Each of the parties hereto agrees<br \/>\nthat a final judgment in any such action or proceeding shall be conclusive and<br \/>\nmay be enforced in other jurisdictions by suit on the judgment or in any other<br \/>\nmanner provided by Law. Each party to this Agreement irrevocably consents to<br \/>\nservice of process in the manner provided for notices in Section 9.2. Nothing in<br \/>\nthis Agreement shall affect the right of any party to this Agreement to serve<br \/>\nprocess in any other manner permitted by Law.<\/p>\n<p>     (c) EACH PARTY ACKNOWLEDGES AND AGREES THAT ANY CONTROVERSY WHICH MAY ARISE<br \/>\nUNDER THIS AGREEMENT IS LIKELY TO INVOLVE COMPLICATED AND DIFFICULT ISSUES, AND<br \/>\nTHEREFORE IT HEREBY IRREVOCABLY AND UNCONDITIONALLY WAIVES ANY RIGHT IT MAY HAVE<br \/>\nTO A TRIAL BY JURY IN RESPECT OF ANY LITIGATION DIRECTLY OR INDIRECTLY ARISING<br \/>\nOUT OF OR RELATING TO THIS AGREEMENT AND ANY OF THE AGREEMENTS DELIVERED IN<br \/>\nCONNECTION HEREWITH OR THE TRANSACTIONS CONTEMPLATED HEREBY OR THEREBY. EACH<br \/>\nPARTY CERTIFIES AND ACKNOWLEDGES THAT (A) NO REPRESENTATIVE, AGENT OR ATTORNEY<br \/>\nOF ANY OTHER PARTY HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH OTHER<br \/>\nPARTY WOULD NOT, IN THE EVENT OF LITIGATION, SEEK TO ENFORCE EITHER OF SUCH<br \/>\nWAIVERS, (B) IT UNDERSTANDS AND HAS CONSIDERED THE IMPLICATIONS OF SUCH WAIVERS,<br \/>\n(C) IT MAKES SUCH WAIVERS VOLUNTARILY, AND (D) IT HAS BEEN INDUCED TO ENTER INTO<br \/>\nTHIS AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND CERTIFICATIONS IN<br \/>\nTHIS SECTION 9.11(c).<\/p>\n<p>                                       62<\/p>\n<p>     Section 9.12  Specific Performance. The parties hereto agree that<br \/>\n                   &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;<br \/>\nirreparable damage would occur in the event any of the provisions of this<br \/>\nAgreement were not to be performed in accordance with the terms hereof and that<br \/>\nthe parties shall be entitled to specific performance of the terms hereof in<br \/>\naddition to any other remedies at Law or in equity.<\/p>\n<p>     Section 9.13  Disclosure. Any matter disclosed in any section of a party&#8217;s<br \/>\n                   &#8212;&#8212;&#8212;-<br \/>\nDisclosure Letter shall be considered disclosed for other sections of such<br \/>\nDisclosure Letter, but only to the extent such matter on its face would<br \/>\nreasonably be expected to be pertinent to a particular section of a party&#8217;s<br \/>\nDisclosure Letter in light of the disclosure made in such section. The provision<br \/>\nof monetary or other quantitative thresholds for disclosure does not and shall<br \/>\nnot be deemed to create or imply a standard of materiality hereunder.<\/p>\n<p>     Section 9.14  Counterparts. This Agreement may be executed in one or more<br \/>\n                   &#8212;&#8212;&#8212;&#8212;<br \/>\ncounterparts, and by the different parties hereto in separate counterparts, each<br \/>\nof which when executed shall be deemed to be an original but all of which taken<br \/>\ntogether shall constitute one and the same agreement.<\/p>\n<p>                            [Signature page follows]<\/p>\n<p>                                       63<\/p>\n<p>     IN WITNESS WHEREOF, Parent, Merger Sub and the Company have caused this<br \/>\nAgreement to be executed as of the date first written above by their respective<br \/>\nofficers thereunto duly authorized.<\/p>\n<p>                             AMGEN INC.<br \/>\n                             a Delaware corporation<\/p>\n<p>                             By:  \/s\/ Kevin W. Sharer<br \/>\n                                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\n                             Name:  Kevin W. Sharer<br \/>\n                             Title: Chairman of the Board, CEO and President<\/p>\n<p>                             AMS ACQUISITION INC.<br \/>\n                             a Washington corporation<\/p>\n<p>                             By:  \/s\/ Kevin W. Sharer<br \/>\n                                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\n                             Name:  Kevin W. Sharer<br \/>\n                             Title: Chairman of the Board, CEO and President<\/p>\n<p>                             IMMUNEX CORPORATION<br \/>\n                             a Washington corporation<\/p>\n<p>                             By:  \/s\/ Edward V. Fritzky<br \/>\n                                 &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br \/>\n                             Name:  Edward V. Fritzky<br \/>\n                             Title: Chairman, Chief Executive Officer and<br \/>\n                                     President<\/p>\n<p>                [SIGNATURE PAGE &#8212; AGREEMENT AND PLAN OF MERGER]<\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_stopmodifiedupdate":true,"_modified_date":"","_cloudinary_featured_overwrite":false},"corporate_contracts_companies":[6691,7837],"corporate_contracts_industries":[9405],"corporate_contracts_types":[9622,9626],"class_list":["post-43010","corporate_contracts","type-corporate_contracts","status-publish","hentry","corporate_contracts_companies-amgen-inc","corporate_contracts_companies-immunex-corp","corporate_contracts_industries-drugs__biotech","corporate_contracts_types-planning","corporate_contracts_types-planning__merger"],"acf":[],"_links":{"self":[{"href":"https:\/\/corporate.findlaw.com\/legal-api\/wp-json\/wp\/v2\/corporate_contracts\/43010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/corporate.findlaw.com\/legal-api\/wp-json\/wp\/v2\/corporate_contracts"}],"about":[{"href":"https:\/\/corporate.findlaw.com\/legal-api\/wp-json\/wp\/v2\/types\/corporate_contracts"}],"wp:attachment":[{"href":"https:\/\/corporate.findlaw.com\/legal-api\/wp-json\/wp\/v2\/media?parent=43010"}],"wp:term":[{"taxonomy":"corporate_contracts_companies","embeddable":true,"href":"https:\/\/corporate.findlaw.com\/legal-api\/wp-json\/wp\/v2\/corporate_contracts_companies?post=43010"},{"taxonomy":"corporate_contracts_industries","embeddable":true,"href":"https:\/\/corporate.findlaw.com\/legal-api\/wp-json\/wp\/v2\/corporate_contracts_industries?post=43010"},{"taxonomy":"corporate_contracts_types","embeddable":true,"href":"https:\/\/corporate.findlaw.com\/legal-api\/wp-json\/wp\/v2\/corporate_contracts_types?post=43010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}